Results 211 to 220 of about 25,962 (290)

Reactive oxygen species, antioxidants and the regulation of plant development

The FEBS Journal, EarlyView.
The regulation of axillary bud outgrowth by the interplay between phytohormone and redox signals. Axillary bud outgrowth is regulated by cellular energy status and the balance between phytohormones, notably abscisic acid (ABA) and gibberellic acid (GA).
Juwita R. Dewi, Christine H. Foyer, Michael J. Considine   +2 more
wiley   +1 more source

Autoantigen identification in antinuclear antibody-positive usual interstitial pneumonia without known autoantibody through immunoprecipitation-mass spectrometry. [PDF]

ERJ Open Res
Vulsteke JB, De Langhe E, De Sadeleer L, De Crem N, Yserbyt J, Dubbeldam A, Wuyts WA, Bossuyt X.   +7 more
europepmc   +1 more source

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

Biphasic SMN condensates safeguard stress-induced cytoplasmic mislocalization of splicing RNPs. [PDF]

Cell Mol Life Sci
Riedel YL, Dressler J, Schilling MT, Gruss OJ.   +3 more
europepmc   +1 more source

A guide to studying tumour‐T‐cell interactions using in vitro coculture assays

The FEBS Journal, EarlyView.
In vitro tumour‐T‐cell coculture systems provide a controlled way to study how T cells recognise and kill tumour cells. Different tumour models can be combined with antigen‐specific TCR or CAR T cells, while antigen presentation, cytokines, drugs and tumour genetics can be manipulated.
Nooshin Khoshdoozmasouleh, Conor J. Kearney   +1 more
wiley   +1 more source

CRISPR-Cas Technology Turns <i>Chlamydomonas reinhardtii</i> into a Flagship for Algal Biotechnology. [PDF]

Mar Drugs
Antonacci A, Masi A, Vedi V, Colella S, Musella F, Fiorentino G, Scognamiglio V.   +6 more
europepmc   +1 more source

Gene Editing for Haemophilia—The Next Frontier

Haemophilia, EarlyView.
ABSTRACT The recently approved haemophilia A and B gene therapies via adeno‐associated virus (AAV) showed a promising therapeutic response after a single injection, but there are still limitations, including the potential loss of transgene expression and restriction in adults.
Mirko Pinotti, Gregory A. Newby, Sundar Selvaraj, Steven W. Pipe   +3 more
wiley   +1 more source

Beyond Permanent Genome Editing: Molecular Delivery Strategies for RNA Editing and Epigenome-Editing Therapeutics. [PDF]

Int J Mol Sci
Zaman W, Ayaz A.
europepmc   +1 more source

A CRISPR‐Based Rapid Detection Assay for Crayfish Plague (Aphanomyces astaci) From Environmental Samples

Journal of Fish Diseases, EarlyView.
ABSTRACT Crayfish plague, caused by Aphanomyces astaci (Aa), is an infectious disease invasive in Europe, where its rapid spread has resulted in sharp declines of native crayfish species. Monitoring currently relies on a highly sensitive, but costly and time‐consuming qPCR approach.
Christopher Heine, Amadeus Plewnia, David Strand, Simran Gupta, Henrik Krehenwinkel, Gus R. McFarlane   +5 more
wiley   +1 more source