Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
The enigma of nuclear FMRP: facts and myths. [PDF]
Khandjian EW, Davidovic L.
europepmc +1 more source
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Regulation of Pre-rRNA Processing in Plant: Mechanisms, Plasticity, and Developmental Implications. [PDF]
Chen N, Huang S, Mo B, Xiong W.
europepmc +1 more source
PTBP1 is upregulated in response to Zika virus infection and restrains viral replication by hijacking viral NS1 protein to induce NS1 degradation. [PDF]
Rao M +7 more
europepmc +1 more source
Retrointegration2023-Papers from the 7th International Conference on Retroviral Integration. [PDF]
Engelman AN +4 more
europepmc +1 more source
Generation of transgene-free genome-edited carrot plants using CRISPR/Cas9-RNP complexes. [PDF]
Yarra R, Krysan PJ.
europepmc +1 more source
Safe and Efficient CRISPR Genome Editing of Primary Human T Cells Using a Droplet-Based Cell Mechanoporation Platform. [PDF]
Kim YJ, Bang S, Chung AJ.
europepmc +1 more source
Influenza A virus induces PI4P production at the endoplasmic reticulum in an ATG16L1-dependent manner to promote the egress of viral ribonucleoproteins. [PDF]
Alemany C +12 more
europepmc +1 more source
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Biogenesis of small nucleolar ribonucleoproteins
Current Opinion in Cell Biology, 2002Eukaryotic cells contain a very complex population of small nucleolar RNAs. They function, as small nucleolar ribonucleoproteins, in pre-ribosomal RNA processing reactions, and also guide methylation and pseudouridylation of ribosomal RNA, spliceosomal small nuclear RNAs, and possibly other cellular RNAs.
Witold Filipowicz
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