Results 1 to 10 of about 26,264 (280)
DFT Based QSAR Study of Enzyme Ribonucleoside Diphosphate Reductase [PDF]
E-Journal of Chemistry, 2010 Quantum chemical descriptors such as heat of formation, energy of HOMO, total energy, absolute hardness and chemical potential in different combinations have been used to develop QSAR models of inhibitors of enzyme ribonucleoside diphosphate reductase ...
Mohiuddin Ansari +2 more
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Characterizing Benzo[a]pyrene Adducts in Transfer RNAs Using Liquid Chromatography Coupled with Tandem Mass Spectrometry (LC-MS/MS) [PDF]
Biomedicines, 2023 The activated forms of the environmental pollutant benzo[a]pyrene (B[a]P), such as benzo[a]pyrene diol epoxide (BPDE), are known to cause damage to genomic DNA and proteins. However, the impact of BPDE on ribonucleic acid (RNA) remains unclear.
Cassandra Herbert +4 more
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AMP‐dependent kinase stimulates the expression of αKlotho [PDF]
FEBS Open BioRenal αKlotho along with fibroblast growth factor 23 regulates phosphate and vitamin D metabolism. Its cleavage yields soluble Klotho controlling intracellular processes.
Julia Vogt +4 more
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Pyrimidine Biosynthesis and Ribonucleoside Metabolism in Species of Pseudomonas
Fermentation, 2023 Pyrimidine biosynthesis and ribonucleoside metabolism in species of Pseudomonas was the focus of this review, in relation to their current taxonomic assignments in different homology groups.
Thomas P. West
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Ribonucleoside Hydrolases–Structure, Functions, Physiological Role and Practical Uses
Biomolecules, 2023 Ribonucleoside hydrolases are enzymes that catalyze the cleavage of ribonucleosides to nitrogenous bases and ribose. These enzymes are found in many organisms: bacteria, archaea, protozoa, metazoans, yeasts, fungi and plants.
Leonid A. Shaposhnikov +3 more
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Molecular Ecology, EarlyView., 2023 Abstract Malaria is a mosquito‐borne disease caused by protozoans of the genus Plasmodium that affects both humans and wildlife. The fitness consequences of infections by avian malaria are well known in birds, however, little information exists on its impact on mosquitoes.
Marta Garrigós +4 more
wiley +1 more source
Journal of Analytical Science and Technology, 2020 With the ability to differentiate different molecular sizes, ion mobility spectrometry (IMS) has great potentials in the analysis of isomeric compounds. However, due to the lack of sensitivity and resolution, IMS has not been commonly used.
Hongzhou Wang +2 more
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Remdesivir increases mtDNA copy number causing mild alterations to oxidative phosphorylation
Scientific Reports, 2023 SARS-CoV-2 causes the severe respiratory disease COVID-19. Remdesivir (RDV) was the first fast-tracked FDA approved treatment drug for COVID-19. RDV acts as an antiviral ribonucleoside (adenosine) analogue that becomes active once it accumulates ...
Nicole DeFoor +9 more
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RRM2 expression in different molecular subtypes of breast cancer and its prognostic significance
Diagnostic Pathology, 2022 Background Breast cancer is one of the most common types of cancer. Ribonucleotide reductase (RNR) is a heterodimeric tetramer consisting of two Ribonucleoside-diphosphate reductase large subunits (RRM1) and two Ribonucleoside-diphosphate reductase small
Manar Ahmed Abdel-Rahman +2 more
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PLoS Pathogens, 2012 Ribonucleoside analogues have potential utility as anti-viral, -parasitic, -bacterial and -cancer agents. However, their clinical applications have been limited by off target effects.
Jamie J Arnold +18 more
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