Results 61 to 70 of about 26,264 (280)

HILIC-MS/MS Analysis of Adenosine in Patient Blood

Separations, 2021
Adenosine is a purine ribonucleoside with important roles in various physiological processes. A number of studies have indicated the importance of adenosine in cardiovascular diseases including syncope; however, the accurate determination of adenosine in
Christina Virgiliou, Nikolaos Fragakis, Melani Sotiriadou, Vassilios Vassilikos, Spiros Gerou, Georgios Theodoridis, Helen Gika   +6 more
doaj   +1 more source

Innovative Cyclic Nucleotides – Nucleoside 2′,3′‐Seven‐Membered Cyclic Diphosphonate Derivatives. Theoretical Feasibility, Synthesis, and Properties

Chemistry – A European Journal, EarlyView.
First report on 7‐membered cyclic nucleotides, 2',3'‐cNTDPs, obtained from all‐natural free ribonucleosides in robust, step‐economic synthesis involving instantaneous and regio‐selective reaction. DFT calculations confirmed the feasibility of 7‐membered cyclic nucleotide formation and deciphered the basis for regioselectivity.
Sveta Liberman, Lea Bobot, Hadar T Ben Daniel, Dan T Major, Bilha Fischer   +4 more
wiley   +1 more source

Regulation of translation by methylation multiplicity of 18S rRNA

Cell Reports, 2021
Summary: N6-methyladenosine (m6A) is a conserved ribonucleoside modification that regulates many facets of RNA metabolism. Using quantitative mass spectrometry, we find that the universally conserved tandem adenosines at the 3′ end of 18S rRNA, thought ...
Kuanqing Liu, Daniel A. Santos, Jeffrey A. Hussmann, Yun Wang, Benjamin M. Sutter, Jonathan S. Weissman, Benjamin P. Tu   +6 more
doaj  

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

Drug Testing and Analysis, EarlyView.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis, Tiia  Kuuranne, Hans  Geyer   +2 more
wiley   +1 more source

Decoding RNA–Protein Interactions: Methodological Advances and Emerging Challenges

Advanced Genetics, EarlyView.
This review provides a comprehensive comparison of RNA‐ and protein‐centric methodologies for investigating RNA–protein interactions, emphasizing their respective advantages, limitations, and suitable applications. It highlights recent technological innovations, outlines strategic method selection criteria, and addresses key challenges.
Wenkai Yi, Jian Yan
wiley   +1 more source

Degradation of nucleic acids with ozone. I. Degradation of nucleobases,ribonucleosides and ribonucleoside-5'-monophosphates.

Chemical and Pharmaceutical Bulletin, 1981
The degradation of nucleobases, ribonucleosides and ribonucleotides with ozone was examined as a model of the action of ozone on nucleic acids. The degradation rates of nucleobases were in the following order : G, T>U>C>A. Nucleosides and nucleotides were degraded in the same order as in the corresponding nucleobases.
Tohru Ueda, Akira Ikehata, Kozo Ishizaki, Nariko Shinriki   +3 more
openaire   +3 more sources

Control of Nucleotide Metabolism and Ribosomal Ribonucleic Acid Synthesis During Nitrogen Starvation of \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]

, 1972
Ribosomal ribonucleic acid (RNA) synthesis and ribonucleoside triphosphate metabolism were studied in cultures of Escherichia coli subjected to starvation for inorganic nitrogen.
Irr, Joseph D.
core   +1 more source

Direct comparison of nick-joining activity of the nucleic acid ligases from bacteriophage T4 [PDF]

, 2006
The genome of bacteriophage T4 encodes three polynucleotide ligases, which seal the backbone of nucleic acids during infection of host bacteria. The T4Dnl (T4 DNA ligase) and two RNA ligases [T4Rnl1 (T4 RNA ligase 1) and T4Rnl2] join a diverse array of ...
Amitsur, Arabshahi, Bebenek, Begley, Bellacosa, Blondal, Blondal, Cherepanov, Cherepanov, Clepet, Della, Desmond R. Bullard, Doherty, Engler, Fareed, Higgins, Ho, Ho, Kaufmann, Keppetipola, Kornberg, Kuhn, Lavesa-Curto, Lehman, Markham, Martins, Martins, Miller, Moore, Nandakumar, Nandakumar, Nandakumar, Nick McElhinny, Omari, Pascal, Pitcher, Pitcher, Richard P. Bowater, Rossi, Ruiz, Runnels, Rydberg, Sambrook, Sekiguchi, Shuman, Shuman, Snopek, Sriskanda, Stuart, Timson, Tomkinson, Wang, Wang, Weiss, Wilkinson, Wilkinson, Wilkinson, Wood, Wood, Worthey, Yin, Yin   +61 more
core   +4 more sources

Overexpression of Phosphoribosyl Pyrophosphate Synthase Enhances Resistance of Chlamydomonas to Ionizing Radiation

Frontiers in Plant Science, 2021
The enzyme phosphoribosyl pyrophosphate synthase (PRPS) catalyzes the conversion of ribose 5-phosphate into phosphoribosyl diphosphate; the latter is a precursor of purine and pyrimidine nucleotides.
Sera Jung, Sera Jung, Kwang Min Koo, Jaihyunk Ryu, Inwoo Baek, Soon-Jae Kwon, Jin-Baek Kim, Joon-Woo Ahn   +7 more
doaj   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source