Results 91 to 100 of about 7,940 (153)
This study identified DNA viruses from Qiangyong proglacial lake sediments on the Tibetan Plateau, revealing a highly diverse and previously uncharacterized viral community. These viruses influence microbial community structure and function by infecting key nutrient‐transforming taxa and encoding auxiliary metabolic genes that modulate host metabolism.
Yang Zhao +6 more
wiley +1 more source
Flavones and Aminoflavones Increase the Cytotoxicity of NK Cells in Human Non‐Small Cell Lung Cancer
ABSTRACT Natural flavonoids (flavones) and synthetic aminoflavones are known for their anti‐cancer properties; however, their immunomodulation ability has been largely unexplored. This study determined that synthetic flavones and aminoflavones modulate the cytotoxicity of natural killer (NK) cells against lung cancer cells.
Ping‐Chih Hsu +4 more
wiley +1 more source
Protecting Groups for the Synthesis of Ribonucleic Acids
Methods for the regioselective introduction of alkoxymethyl-groups into the 2?-O-position of 5?-O-dimethoxytritylated, nucleobase-protected ribonucleosides and for the N-alkyloxycarbonylation of adenine and guanine nucleosides were developed ...
Stefan Pitsch
doaj
Chemical synthesis of novel taurine-containing uridine derivatives [PDF]
Recently, novel taurine-containing uridine derivatives were discovered in mammalian mitochondrial tRNAs, and these modified ribonucleosides existed at the first position of the anti-codon.
777 +15 more
core +1 more source
ABSTRACT Selfing often causes inbreeding depression, especially during seed and seedling stages. However, some selfed progeny show low inbreeding depression with enhanced vigour, differing from inbred counterparts. This study investigates the molecular mechanisms maintaining seed vigour during selfing in Cunninghamia lanceolata.
Houyin Deng +13 more
wiley +1 more source
Metal species and carbonate are often found as minerals in extraterrestrial rocky bodies. Based on this, the mechanochemical-induced degradation of canonical purine and pyrimidine ribonucleosides into their corresponding nucleobases mediated by some of ...
Gustavo P. Maia +7 more
doaj +1 more source
Aromatic N versus aromatic F : bioisosterism discovered in RNA base pairing interactions leads to a novel class of universal base analogs [PDF]
The thermodynamics of base pairing is of fundamental importance. Fluorinated base analogs are valuable tools for investigating pairing interactions. To understand the influence of direct base–base interactions in relation to the role of water, pairing ...
Alrun N. Koller +74 more
core +1 more source
Position-dependent effects on stability in tricyclo-DNA modified oligonucleotide duplexes [PDF]
A series of oligodeoxyribonucleotides and oligoribonucleotides containing single and multiple tricyclo(tc)-nucleosides in various arrangements were prepared and the thermal and thermodynamic transition profiles of duplexes with complementary DNA and RNA ...
Gerber, Anna-Barbara +2 more
core
The complex relationship between the gut microbiome and host metabolic health has been an emerging research area. Several recent studies have highlighted the potential effects of the microbiome’s diversity, composition and metabolic production ...
Ayya Keshet, Eran Segal
doaj +1 more source

