Results 91 to 100 of about 9,338 (256)

Protecting Groups for the Synthesis of Ribonucleic Acids

open access: yesCHIMIA, 2001
Methods for the regioselective introduction of alkoxymethyl-groups into the 2?-O-position of 5?-O-dimethoxytritylated, nucleobase-protected ribonucleosides and for the N-alkyloxycarbonylation of adenine and guanine nucleosides were developed ...
Stefan Pitsch
doaj  

Multi‐omics analysis of the regulatory network in winter buds of ‘Cabernet Sauvignon’ grapevine from dormancy to bud break

open access: yesPlant Biotechnology Journal, Volume 23, Issue 6, Page 2110-2124, June 2025.
Summary Winter dormancy and bud break are crucial to the viability, adaptability and yield of fruit trees, but not all metabolic activities or regulatory factors involved in maintaining and breaking dormancy are known. Here, winter buds, spanning from natural dormancy to bud break, were collected from ‘Cabernet Sauvignon’ grapevines maintained outdoors
Li Chen   +5 more
wiley   +1 more source

Mechanochemical Reactivity of Ribonucleosides Mediated by Inorganic Species: Implications for Extraterrestrial Organic Matter Interpretation

open access: yesApplied Sciences
Metal species and carbonate are often found as minerals in extraterrestrial rocky bodies. Based on this, the mechanochemical-induced degradation of canonical purine and pyrimidine ribonucleosides into their corresponding nucleobases mediated by some of ...
Gustavo P. Maia   +7 more
doaj   +1 more source

In vitro DNA/RNA Adductomics to Confirm DNA Damage Caused by Benzo[a]pyrene in the Hep G2 Cell Line

open access: yesFrontiers in Chemistry, 2019
In the development of new chemical substances, genetic toxicity evaluations are a high priority for safety risk management. Evaluation of the possibility of compound carcinogenicity with accuracy and at reasonable cost in the early stages of development ...
Toshihide Takeshita, Robert A. Kanaly
doaj   +1 more source

Chemical synthesis of novel taurine-containing uridine derivatives [PDF]

open access: yes, 1905
Recently, novel taurine-containing uridine derivatives were discovered in mammalian mitochondrial tRNAs, and these modified ribonucleosides existed at the first position of the anti-codon.
777   +15 more
core   +1 more source

Chiral Materials from Biomass: 3‐deoxy‐α‐D‐ribono‐1,4‐lactone and 3‐deoxy‐α‐D‐arabino‐1,4‐lactone via the Bromination of Cyrene

open access: yesEuropean Journal of Organic Chemistry, Volume 28, Issue 19, May 27, 2025.
The biomass pyrolysis product levoglucosenone enables the preparation of the feeding modulator 3‐deoxy‐d‐arabino‐1,4‐lactone and the diastereomer 3‐deoxy‐d‐ribono‐1,4‐lactone. The key steps involve a diastereoselective bromination using an enamine bromination‐hydrolysis strategy on the bicyclic ring‐system followed by selective nucleophilic ...
Johannes Puschnig   +2 more
wiley   +1 more source

Applications of Microwave in Organic Synthesis: A One-step Synthesis of Ribonucleosides using natural phosphate as solid catalyst [PDF]

open access: yes, 2013
A clean, efficient and fast method for synthesis of ribonucleosides was developed, using  natural phosphate as solid catalyst catalysts supported in a solid phase  promoted by MW irradiation.
Lazrek, Hassan B.   +3 more
core   +1 more source

Nucleotides: Structure and Properties [PDF]

open access: yes, 2005
Nucleotides consist of a nitrogen-containing base, a five-carbon sugar, and one or more phosphate groups. Cells contain many types of nucleotides, which play a central role in a wide variety of cellular processes, including metabolic regulation and the ...
Bowater, RP
core   +1 more source

INTRACELLULAR Leishmania amazonensis KILLING INDUCED BY THE GUANINE NUCLEOSIDE 8-BROMOGUANOSINE

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1998
In this study we investigated the effect of 8-Bromoguanosine, an immunostimulatory compound, on the cytotoxicity of macrophages against Leishmania amazonensis in an in vitro system. The results showed that macrophages treated with 8-Bromoguanosine before
GIORGIO Selma, BARÃO Sandra C.
doaj  

Metabolic turnover and dynamics of modified ribonucleosides by ¹³C labeling [PDF]

open access: yes, 2021
Tandem mass spectrometry (MS/MS) is an accurate tool to assess modified ribonucleosides and their dynamics in mammalian cells. However, MS/MS quantification of lowly abundant modifications in non-ribosomal RNAs is unreliable, and the dynamic features of ...
Dos Santos, MS   +4 more
core  

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