Results 81 to 90 of about 5,924 (208)

Mechanochemical Reactivity of Ribonucleosides Mediated by Inorganic Species: Implications for Extraterrestrial Organic Matter Interpretation

open access: yesApplied Sciences
Metal species and carbonate are often found as minerals in extraterrestrial rocky bodies. Based on this, the mechanochemical-induced degradation of canonical purine and pyrimidine ribonucleosides into their corresponding nucleobases mediated by some of ...
Gustavo P. Maia   +7 more
doaj   +1 more source

Hetaryl derivatives of 7-deazapurine ribonucleosides: potent cytostatic agents

open access: yes, 2011
A series of novel 7-deazapurine ribonucleosides substituted with aryl and hetaryl groups has been prepared. Suzuki or Stille cross-coupling reactions with 6-chloro-7-deazapurine ribonucleosides substituted with H, F of Cl atom in position 7 were used ...
Perlíková, Pavla
core  

A New Selective Synthesis Of D-Ribonucleosides In Acetonitrile With BSA Using NP/KI As Catalyst [PDF]

open access: yes, 2013
The one-step synthesis of several ?-D-ribonucleosides was performed in good yields under reflux.
Smietana, Michael   +3 more
core  

A Convenient Synthesis of Ribonucleoside 2', 3', -Cyclic Phosphates from Ribonucleosides and Ribonucleotides

open access: yesChemical and Pharmaceutical Bulletin, 1970
Adenosine 5'-phosphate was converted to the 2', 3'-cyclic phosphate by the treatment with dimethylformamide at reflux temperature. The reaction was shown to be proceeded by the initial release of the phosphoryl group as an"activated phosphoric acid"and rephosphorylated to furnish the 2', 3'-cyclic phosphate. In fact a ribonucleoside and phosphoric acid,
UEDA, TOHRU, KAWAI, IKUKO
openaire   +2 more sources

A General and Efficient Synthesis of Pyridin-2-yl C-Ribonucleosides Bearing Diverse Alkyl, Aryl, Amino, and Carbamoyl Groups in Position 6

open access: yes, 2016
An efficient and practical methodology of preparation of 6-substituted pyridin-2-yl C-ribonucleosides was developed. A one-pot two-step addition of 2-lithio-6-bromopyridine to TBS-protected ribonolactone followed by acetylation gave 1β-(6-bromopyridin-2 ...
Michal Hocek (1365984)   +3 more
core   +2 more sources

In vitro DNA/RNA Adductomics to Confirm DNA Damage Caused by Benzo[a]pyrene in the Hep G2 Cell Line

open access: yesFrontiers in Chemistry, 2019
In the development of new chemical substances, genetic toxicity evaluations are a high priority for safety risk management. Evaluation of the possibility of compound carcinogenicity with accuracy and at reasonable cost in the early stages of development ...
Toshihide Takeshita, Robert A. Kanaly
doaj   +1 more source

Antimicrobial Activity of Synthetic 5'-amino Ribonucleosides

open access: yes, 2016
No abstract available.“Antimicrobial Activity of Synthetic 5’-amino Ribonucleosides.” with R. Van Ostrand and A. Chavez. Poster delivered at 251st ACS National Meeting & Exposition. San Diego, California.
Ahmed Awad
core  

INTRACELLULAR Leishmania amazonensis KILLING INDUCED BY THE GUANINE NUCLEOSIDE 8-BROMOGUANOSINE

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1998
In this study we investigated the effect of 8-Bromoguanosine, an immunostimulatory compound, on the cytotoxicity of macrophages against Leishmania amazonensis in an in vitro system. The results showed that macrophages treated with 8-Bromoguanosine before
GIORGIO Selma, BARÃO Sandra C.
doaj  

Synthesis of Azido Ribonucleosides for Antimicrobial Applications

open access: yes, 2015
No abstract available.“Synthesis of Azido Ribonucleosides for Antimicrobial Applications.” with A. Hernandez, D. Stevenson, and G. Tolentino. Poster delivered at Southern California Conference on Undergraduate Research.
Ahmed Awad
core  

Synthesis of Differently Protected 1-C-Methyl-Ribofuranoses Intermediates for the Preparation of Biologically Active 1'-C-Methyl-Ribonucleosides

open access: yes, 2008
Starting from D-ribose, differently protected 1-C-methyl-D-ribofuranoses have been prepared as intermediates for the synthesis of variously modified 1'-C-methyl-ribonucleosides, a class of compounds potentially endowed with interesting biological ...
E. Santaniello   +4 more
core   +1 more source

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