Results 81 to 90 of about 5,924 (208)
Metal species and carbonate are often found as minerals in extraterrestrial rocky bodies. Based on this, the mechanochemical-induced degradation of canonical purine and pyrimidine ribonucleosides into their corresponding nucleobases mediated by some of ...
Gustavo P. Maia +7 more
doaj +1 more source
Hetaryl derivatives of 7-deazapurine ribonucleosides: potent cytostatic agents
A series of novel 7-deazapurine ribonucleosides substituted with aryl and hetaryl groups has been prepared. Suzuki or Stille cross-coupling reactions with 6-chloro-7-deazapurine ribonucleosides substituted with H, F of Cl atom in position 7 were used ...
Perlíková, Pavla
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A New Selective Synthesis Of D-Ribonucleosides In Acetonitrile With BSA Using NP/KI As Catalyst [PDF]
The one-step synthesis of several ?-D-ribonucleosides was performed in good yields under reflux.
Smietana, Michael +3 more
core
Adenosine 5'-phosphate was converted to the 2', 3'-cyclic phosphate by the treatment with dimethylformamide at reflux temperature. The reaction was shown to be proceeded by the initial release of the phosphoryl group as an"activated phosphoric acid"and rephosphorylated to furnish the 2', 3'-cyclic phosphate. In fact a ribonucleoside and phosphoric acid,
UEDA, TOHRU, KAWAI, IKUKO
openaire +2 more sources
An efficient and practical methodology of preparation of 6-substituted pyridin-2-yl C-ribonucleosides was developed. A one-pot two-step addition of 2-lithio-6-bromopyridine to TBS-protected ribonolactone followed by acetylation gave 1β-(6-bromopyridin-2 ...
Michal Hocek (1365984) +3 more
core +2 more sources
In vitro DNA/RNA Adductomics to Confirm DNA Damage Caused by Benzo[a]pyrene in the Hep G2 Cell Line
In the development of new chemical substances, genetic toxicity evaluations are a high priority for safety risk management. Evaluation of the possibility of compound carcinogenicity with accuracy and at reasonable cost in the early stages of development ...
Toshihide Takeshita, Robert A. Kanaly
doaj +1 more source
Antimicrobial Activity of Synthetic 5'-amino Ribonucleosides
No abstract available.“Antimicrobial Activity of Synthetic 5’-amino Ribonucleosides.” with R. Van Ostrand and A. Chavez. Poster delivered at 251st ACS National Meeting & Exposition. San Diego, California.
Ahmed Awad
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INTRACELLULAR Leishmania amazonensis KILLING INDUCED BY THE GUANINE NUCLEOSIDE 8-BROMOGUANOSINE
In this study we investigated the effect of 8-Bromoguanosine, an immunostimulatory compound, on the cytotoxicity of macrophages against Leishmania amazonensis in an in vitro system. The results showed that macrophages treated with 8-Bromoguanosine before
GIORGIO Selma, BARÃO Sandra C.
doaj
Synthesis of Azido Ribonucleosides for Antimicrobial Applications
No abstract available.“Synthesis of Azido Ribonucleosides for Antimicrobial Applications.” with A. Hernandez, D. Stevenson, and G. Tolentino. Poster delivered at Southern California Conference on Undergraduate Research.
Ahmed Awad
core
Starting from D-ribose, differently protected 1-C-methyl-D-ribofuranoses have been prepared as intermediates for the synthesis of variously modified 1'-C-methyl-ribonucleosides, a class of compounds potentially endowed with interesting biological ...
E. Santaniello +4 more
core +1 more source

