Design, synthesis, conformational analysis and nucleic acid hybridisation properties of thymidyl pyrrolidine-amide oligonucleotide mimics (POM) [PDF]
, 2003 Pyrrolidine-amide oligonucleotide mimics (POM) 1 were designed to be stereochemically and conformationally similar to natural nucleic acids, but with an oppositely charged, cationic backbone.
Cooper, M.A. +5 more
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Natural Product 4‐Acetylantroquinonol B Enhances NK Cell‐Mediated Immunity Against Glioblastoma
Cancer Medicine, Volume 15, Issue 4, April 2026.Combined 4‐AAQB and NK therapy suppresses glioblastoma growth in vivo by inducing a distinct tumor stress state characterized by proteostasis disruption and autophagy‐associated programs, thereby sensitizing tumors to immune‐mediated control. ABSTRACT Glioblastoma (GBM) recurs rapidly despite surgery and radiochemotherapy and is associated with ...
Yuan‐Chieh Yeh +4 more
wiley +1 more source
Diverse cell stresses induce unique patterns of tRNA up- and down-regulation: tRNA-seq for quantifying changes in tRNA copy number [PDF]
, 2014 Emerging evidence points to roles for tRNA modifications and tRNA abundance in cellular stress responses. While isolated instances of stress-induced tRNA degradation have been reported, we sought to assess the effects of stress on tRNA levels at a ...
Abo, Ryan +3 more
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eFood, Volume 7, Issue 2, April 2026.An integrative approach of network pharmacology, molecular docking, and MSC proliferation confirmation was performed to elucidate the mechanism of SSG in treating osteoporosis. Fewer free isoflavones but more glucuronide metabolites were detected in plasma.
Rezeye Aili, Hong Chen, Feng Qiu
wiley +1 more source
The Development of a Direct Homologous Radioimmunoassay for Serum Cortisol [PDF]
, 1981 Peer ...
Giesemann, G. +4 more
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Human Brain Mapping, Volume 47, Issue 5, 1 April 2026.Long‐term hearing loss with cognitive decline shows altered brain gradients, enlarged choroid plexus, and ventricles. These are linked to transcriptomic changes in synaptic, metabolic, and neurodegenerative pathways. ABSTRACT Long‐term sensorineural hearing loss (SNHL) is a prevalent condition associated with an increased risk of cognitive impairment ...
Xiao‐Min Xu +8 more
wiley +1 more source
A General Method for Selective Tritylation of Primary Hydroxyl Groups in Carbohydrates and Related Compounds [PDF]
Journal of Sciences, Islamic Republic of Iran, 1989 A general and rapid procedure is developed for the selective tritylation of the 'primary OH-function of the four common ribonucleosides, ascorbic acid, and polyhydric compounds.
doaj
18F-FAC PET Visualizes Brain-Infiltrating Leukocytes in a Mouse Model of Multiple Sclerosis. [PDF]
, 2020 Brain-infiltrating leukocytes contribute to multiple sclerosis (MS) and autoimmune encephalomyelitis and likely play a role in traumatic brain injury, seizure, and stroke.
Chen, Bao Ying +6 more
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MedComm, Volume 7, Issue 4, April 2026.iPSC‐derived corneal endothelial cells purified via a novel wash‐out method show high functional fidelity, resemble primary CECs, and restore corneal clarity in vivo, offering a scalable alternative to donor transplantation. ABSTRACT Corneal endothelial failure can cause blindness, with transplantation as the only treatment.
Eun‐Ah Ye +10 more
wiley +1 more source
Comparative analysis of Bacillus weihenstephanensis KBAB4 spores obtained at different temperatures [PDF]
, 2010 The impact of Bacillus weihenstephanensis KBAB4 sporulation temperature history was assessed on spore heat resistance, germination and outgrowth capacity at a temperature range from 7 to 30 °C. Sporulation rate and efficiency decreased at low temperature,
Abee, T., Garcia, D., Voort, M., van der
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