Results 61 to 70 of about 8,043 (217)

Stimuli-responsive releasing of gold nanoparticles and liposomes from aptamer-functionalized hydrogels [PDF]

, 2011
This is an author-created, un-copyedited version of an article accepted for publication/published in Nanotechnology. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it.
Dave, Neeshma, El-Hamed, Firas, Liu, Juewen   +2 more
core   +1 more source

Synthesis of [5‘-¹³C]Ribonucleosides and 2‘-Deoxy[5‘-¹³C]ribonucleosides [PDF]

The Journal of Organic Chemistry, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Etsuko, Kawashima, Kaoru, Umabe, Takeshi, Sekine   +2 more
openaire   +2 more sources

5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng, Dandan Li, Yunyi Li, Chen Yun, Xinzhou Zhang, Wenyu Gong, Mengyun Xiao, Haitao Li, Zhipeng Zeng, Ruqi Tan, Yishen Yang, Shaodong Luan, Yong Dai, Lianghong Yin, Donge Tang   +14 more
wiley   +1 more source

Aromatic N versus aromatic F : bioisosterism discovered in RNA base pairing interactions leads to a novel class of universal base analogs [PDF]

, 2010
The thermodynamics of base pairing is of fundamental importance. Fluorinated base analogs are valuable tools for investigating pairing interactions. To understand the influence of direct base–base interactions in relation to the role of water, pairing ...
Alrun N. Koller, Jelena Božilović, Joachim W. Engels, Holger Gohlke, Schweitzer, Loakes, Parsch, Lai, Somoza, Murray-Rust, Dunitz, Dunitz, Kool, O'H, Olsen, Olsen, Olsen, Müller, Thalladi, Desiraju, Reichenbächer, Kopitz, Turner, Stofer, Freier, Turner, Tanner, Kierzek, Vesnaver, Levitt, Arora, Cubero, Meyer, Ryjácek, Cubero, Florian, Bats, Živković, Klöpffer, Živković, Bégué, Bayly, Cornell, Müller, Torrie, Case, Šponer, Šponer, Šponer, Jorgensen, Berendsen, Ryckaert, Darden, Bouzida, Efron, MacCallum, Varani, Buckin, Gao, Kool, Šponer, Barsky, Zacharias, Ran, Smart, Jeffrey, Bondi, Hof, Jakobi, Eritja, Parsch, Vorbrüggen, Furneaux, Rolland, Guckian   +74 more
core   +1 more source

Noncanonical Nucleotides in the Genome Around the Maternal‐Zygotic Transition

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In this paper, Kazzazi et al. provide a comprehensive review of the dynamics of nonconventional nucleotides in the genome during early developmental stages, hypothesizing a potential role for these nucleotides in the activation of the zygotic genome. ABSTRACT From the very moment of fertilization and throughout development, the cells of animal embryos ...
Latifa Kazzazy, Dávid Mező, Kinga K. Nagy, Viktória Perey‐Simon, Judit Tóth, Angéla Békési, Beáta Vértessy, Máté Varga   +7 more
wiley   +1 more source

Preparation of a disulfide-linked precipitative soluble support for solution-phase synthesis of trimeric oligodeoxyribonucleotide 3´-(2-chlorophenylphosphate) building blocks

Beilstein Journal of Organic Chemistry, 2015
The preparation of a disulfide-tethered precipitative soluble support and its use for solution-phase synthesis of trimeric oligodeoxyribonucleotide 3´-(2-chlorophenylphosphate) building blocks is described. To obtain the building blocks, N-acyl protected
Amit M. Jabgunde, Alejandro Gimenez Molina, Pasi Virta, Harri Lönnberg   +3 more
doaj   +1 more source

METTL14 Regulates Myocardial Infarction Progression via m6A‐Dependent Modulation of OTUD1‐Mediated Deubiquitination of DUSP6

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial infarction (MI) is the most severe clinical manifestation of coronary artery diseases (CVD) and serves as a critical driver of sudden cardiac death and heart failure (HF). Its pathophysiology begins with the abrupt cessation of coronary blood flow, leading to severe ischemia and subsequent cardiomyocyte necrosis. This study aimed to
Cheng‐Cheng Wei, Ya‐Fang Shen, Jin‐Yu Zhang   +2 more
wiley   +1 more source

Feline thymidine kinase 1: molecular characterization and evaluation of its serum form as a diagnostic biomarker

BMC Veterinary Research, 2021
Background Thymidine kinase 1 (TK1) catalyzes the initial phosphorylation of thymidine in the salvage pathway synthesis of dTTP, an essential building block of DNA. TK1 is a cytosolic enzyme with its highest level during the S-phase of the cell cycle. In
Liya Wang, Hanan Sharif, Sara Saellström, Henrik Rönnberg, Staffan Eriksson   +4 more
doaj   +1 more source

DNA Methylation Shapes Seed‐Borne Microbiome and Proteome Responses During Early Maize‐Beneficial Bacteria Interactions

Plant, Cell &Environment, EarlyView.
ABSTRACT Microorganism and plant interactions are crucial for development and environmental adaptation. Plant growth promoting bacteria enhance agricultural productivity in a sustainable manner, while epigenetic modifications such as DNA methylation regulate gene expression and adaptive responses.
Pedro Igor Zocateli, Geovanna Vitória de Olímpio, Felipe Astolpho de Almeida, Letícia Oliveira da Rocha, Diego Vinicius de Sena Martins, Sara Sangi, Fábio Lopes Olivares, Elyabe Monteiro de Matos, Juliana Siqueira, Lyderson Facio Viccini, Roberta Pena da Paschoa, Vanildo Silveira, Clícia Grativol   +12 more
wiley   +1 more source

Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases

Viruses, 2018
Viral RNA-dependent RNA polymerases (RdRps) play a central role not only in viral replication, but also in the genetic evolution of viral RNAs. After binding to an RNA template and selecting 5′-triphosphate ribonucleosides, viral RdRps synthesize an RNA ...
Barbara Selisko, Nicolas Papageorgiou, François Ferron, Bruno Canard   +3 more
doaj   +1 more source