Results 21 to 30 of about 4,285 (173)
Molecules, 2017 Disaccharide nucleosides are an important class of natural compounds that have a variety of biological activities. In this study, we report on the synthesis of disaccharide nucleosides utilizing the temporary protection of the 2′,3′-cis-diol of ...
Hidehisa Someya, Taiki Itoh, Shin Aoki
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Permeability of Coxiella burnetii to ribonucleosides [PDF]
Microbiology, 2002 Knowledge about transport in Coxiella burnetii, an obligate phagolysosomal parasite, is incomplete. The authors investigated the capability of isolated, intact, host-free Coxiella to transport ribonucleosides while incubated at a pH value typical of lysosomes.
Jeffrey D, Miller, Herbert A, Thompson
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PLoS Biology, 2018 Animals employ various types of taste receptors to identify and discriminate between different nutritious food chemicals. These macronutrients are thought to fall into 3 major groups: carbohydrates/sugars, proteins/amino acids, and fats.
Dushyant Mishra +4 more
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Biomedicines, 2023 The activated forms of the environmental pollutant benzo[a]pyrene (B[a]P), such as benzo[a]pyrene diol epoxide (BPDE), are known to cause damage to genomic DNA and proteins. However, the impact of BPDE on ribonucleic acid (RNA) remains unclear.
Cassandra Herbert +4 more
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Biomimetic Ketone Reduction by Disulfide Radical Anion
Molecules, 2021 The conversion of ribonucleosides to 2′-deoxyribonucleosides is catalyzed by ribonucleoside reductase enzymes in nature. One of the key steps in this complex radical mechanism is the reduction of the 3′-ketodeoxynucleotide by a pair of cysteine residues,
Sebastian Barata-Vallejo +5 more
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Molecules, 2011 There are more than 100 different ribonucleoside structures incorporated as post-transcriptional modifications, mainly in tRNA and rRNA of both prokaryotes and eukaryotes, and emerging evidence suggests that these modifications function as a system in ...
Peter C. Dedon +8 more
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Ribonucleosides, Aminoacyl- and Peptidyl-RNA: Synthesis, Thermodynamics, and Structure
CHIMIA, 1999 Ribonucleosides, RNA and peptides are prepared to study non-covalent interactions of RNA, aminoacyl- and peptidyl-RNA. Techniques used include chemical synthesis in solution and on solid supports, UV- and NM-detected thermal denaturation, X-ray ...
Ewa Biala +3 more
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Tikrit Journal of Pure Science, 2023 One of the hydrolytic enzymes that catalyzes the hydrolysis of 5' -nucleotides into ribonucleosides and phosphate is the 5'nucleotidase, which is found in several organs.
Sameer M. Al-Gorany +1 more
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Synthesis of New 1,2,3-Triazol-4-yl-quinazoline Nucleoside and Acyclonucleoside Analogues
Molecules, 2014 In this study, we describe the synthesis of 1,4-disustituted-1,2,3-triazolo-quinazoline ribonucleosides or acyclonucleosides by means of 1,3-dipolar cycloaddition between various O or N-alkylated propargyl-quinazoline and 1'-azido-2',3',5'-tri-O ...
Abdelaaziz Ouahrouch +4 more
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MoleculesThe emergence of RNA viruses driven by global population growth and international trade highlights the urgent need for effective antiviral agents that can inhibit viral replication.
Evan Saillard +4 more
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