Results 181 to 190 of about 699,944 (333)
Advanced Science, EarlyView.Lipopolysaccharide induces upregulation of the magnesium (Mg2+) efflux transporter solute carrier family 41 member 1 in dental stem cells, leading to a decrease in intracellular Mg2+ concentration and promoting the binding of oligomycin sensitivity‐conferring protein and cyclophilinD.
Yuan Liu +11 more
wiley +1 more source
Interaction between Denatured DNA and Ribosomal RNA from Bacteria: Characterisation of DNA Sites Interacting with Ribosomal RNA at Room Temperature [PDF]
, 1968 M. Arcà +3 more
openalex +1 more source
Nanomaterials Trigger Functional Anti‐Tumoral Responses in Primary Human Immune Cells
Advanced Science, EarlyView.Nanoparticles are used to improve immunomodulatory therapies, but the impact of drug‐free nanomaterials on the immune system remains unknown. Screening common biomedical nanoparticles (NPs) reveals that PLGA NPs enhanced NK cell anti‐tumoral activity and transcriptional activation in human NK and pan T cells.
Vincent Mittelheisser +20 more
wiley +1 more source
Identifying Tipping Points during Healthy Brain Aging through Single‐Nucleus Transcriptomic Analysis
Advanced Science, EarlyView.This study applies single‐nucleus transcriptomics and systems dynamics to uncover nonlinear aging patterns in healthy human brains. By introducing dynamic network biomarker theory, the authors identify a critical tipping point at ages 56–60 during aging, and highlight glial instability as a key mediator.
Peiru Wu +9 more
wiley +1 more source
Preparation of Highly Immunogenic Ribosomal Fractions ofMycobacterium tuberculosisby Use of Sodium Dodecyl Sulfate [PDF]
, 1966 Anne S. Youmans, Guy P. Youmans
openalex +1 more source
Internal Phase Separation in Synthetic DNA Condensates
Advanced Science, EarlyView.The modular, programmable system of DNA nanostructures developed provides programmatic control over multiphase condensate behavior, enabling mapping onto a predictive Flory‐Huggins model. This combined experimental and theoretical framework will help address open questions in condensate biophysics and facilitate the rational design of functional ...
Diana A. Tanase +5 more
wiley +1 more source
Ribosomes and Ribosomal Protein fromNeurospora crassaI. Physical, Chemical, and Immunochemical Properties [PDF]
, 1967 Lilia Alberghina, Sigmund R. Suskind
openalex +1 more source
Advanced Science, EarlyView.Here, it is revealed that ovarian cancer cells release extracellular vesicles enriched with eIF4E, which alters protein production in macrophages. This leads to increased expression of 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase (HMGCR), boosting cholesterol synthesis and activating an immunosuppressive pathway through X‐box binding protein 1 and ...
Sonam Mittal +15 more
wiley +1 more source
Elucidating the Role of CNOT2 in Regulating Cancer Cell Growth via the Modulation of p53 and c-Myc Expression. [PDF]
Curr Issues Mol BiolLee J +5 more
europepmc +1 more source