Results 11 to 20 of about 846,528 (387)

Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy

open access: yesSignal Transduction and Targeted Therapy, 2021
Ribosome biogenesis and protein synthesis are fundamental rate-limiting steps for cell growth and proliferation. The ribosomal proteins (RPs), comprising the structural parts of the ribosome, are essential for ribosome assembly and function.
Jian Kang   +5 more
semanticscholar   +1 more source

Translational control of one-carbon metabolism underpins ribosomal protein phenotypes in cell division and longevity

open access: yeseLife, 2020
A long-standing problem is how cells that lack one of the highly similar ribosomal proteins (RPs) often display distinct phenotypes. Yeast and other organisms live longer when they lack specific ribosomal proteins, especially of the large 60S subunit of ...
Nairita Maitra   +8 more
doaj   +1 more source

The mitochondrial ribosome and ribosomal RNA of the chick [PDF]

open access: yesFEBS Letters, 1971
Reports have appeared on large molecular weight RNAs associated with the mitochondria of higher organisms. These include HeLa cells [ 1 ] , BHK-2 1 cells [2] , mouse L-cells [3,4] , rat liver [4, S] and Xenopus ovary [6] . This RNA consists of two predominant species found to be 17 S and 13 S by sedimentation [2, 31 .
Rabbitts, Terence H., Work, T.S.
openaire   +2 more sources

The inhibition of ribosomal ribonuclease by bacterial ribosomes [PDF]

open access: yesBiochemical Journal, 1965
1. A comparison has been made between the ribonuclease activities of untreated ribosomes from Escherichia coli B and Pseudomonas fluorescens and the activities of ribosomes on to which ribosomal ribonuclease from E. coli B has been adsorbed. 2. The normal ribosomes from both species were stable in 5-10mm-Mg(2+) (I0.16) at pH6. The RNA in ribosomes from
H E, Wade, H K, Robinson
openaire   +2 more sources

The roles of ribosomal proteins in nasopharyngeal cancer: culprits, sentinels or both

open access: yesBiomarker Research, 2021
Ribosomal protein genes encode products that are essential for cellular protein biosynthesis and are major components of ribosomes. Canonically, they are involved in the complex system of ribosome biogenesis pivotal to the catalysis of protein ...
Edmund Ui-Hang Sim   +2 more
doaj   +1 more source

Truncation of the Mrp20 Protein Reveals New Ribosome‐assembly Subcomplex in Mitochondria [PDF]

open access: yes, 2011
Mitochondrial ribosomal protein 20 (Mrp20) is a component of the yeast mitochondrial large (54S) ribosomal subunit and is homologous to the bacterial L23 protein, located at the ribosomal tunnel exit site.
Kaur, Jasvinder, Stuart, Rosemary A.
core   +2 more sources

The SILVA ribosomal RNA gene database project: improved data processing and web-based tools

open access: yesNucleic Acids Res., 2012
SILVA (from Latin silva, forest, http://www.arb-silva.de) is a comprehensive web resource for up to date, quality-controlled databases of aligned ribosomal RNA (rRNA) gene sequences from the Bacteria, Archaea and Eukaryota domains and supplementary ...
Christian Quast   +7 more
semanticscholar   +1 more source

Nuclear Export of Pre-Ribosomal Subunits Requires Dbp5, but Not as an RNA-Helicase as for mRNA Export. [PDF]

open access: yesPLoS ONE, 2016
The DEAD-box RNA-helicase Dbp5/Rat8 is known for its function in nuclear mRNA export, where it displaces the export receptor Mex67 from the mRNA at the cytoplasmic side of the nuclear pore complex (NPC).
Bettina Neumann   +3 more
doaj   +1 more source

DHAV-1 2A1 Peptide – A Newly Discovered Co-expression Tool That Mediates the Ribosomal “Skipping” Function

open access: yesFrontiers in Microbiology, 2018
Duck hepatitis A virus 1 (DHAV-1) belongs to the genus Avihepatovirus in the family Picornaviridae. Little research has been carried out on the non-structural proteins of this virus.
Xiaoyao Yang   +42 more
doaj   +1 more source

A model for the study of ligand binding to the ribosomal RNA helix h44. [PDF]

open access: yes, 2010
Oligonucleotide models of ribosomal RNA domains are powerful tools to study the binding and molecular recognition of antibiotics that interfere with bacterial translation.
Dibrov, Sergey M   +2 more
core   +3 more sources

Home - About - Disclaimer - Privacy