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Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy
Ribosome biogenesis and protein synthesis are fundamental rate-limiting steps for cell growth and proliferation. The ribosomal proteins (RPs), comprising the structural parts of the ribosome, are essential for ribosome assembly and function.
Jian Kang +5 more
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A long-standing problem is how cells that lack one of the highly similar ribosomal proteins (RPs) often display distinct phenotypes. Yeast and other organisms live longer when they lack specific ribosomal proteins, especially of the large 60S subunit of ...
Nairita Maitra +8 more
doaj +1 more source
The mitochondrial ribosome and ribosomal RNA of the chick [PDF]
Reports have appeared on large molecular weight RNAs associated with the mitochondria of higher organisms. These include HeLa cells [ 1 ] , BHK-2 1 cells [2] , mouse L-cells [3,4] , rat liver [4, S] and Xenopus ovary [6] . This RNA consists of two predominant species found to be 17 S and 13 S by sedimentation [2, 31 .
Rabbitts, Terence H., Work, T.S.
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The inhibition of ribosomal ribonuclease by bacterial ribosomes [PDF]
1. A comparison has been made between the ribonuclease activities of untreated ribosomes from Escherichia coli B and Pseudomonas fluorescens and the activities of ribosomes on to which ribosomal ribonuclease from E. coli B has been adsorbed. 2. The normal ribosomes from both species were stable in 5-10mm-Mg(2+) (I0.16) at pH6. The RNA in ribosomes from
H E, Wade, H K, Robinson
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The roles of ribosomal proteins in nasopharyngeal cancer: culprits, sentinels or both
Ribosomal protein genes encode products that are essential for cellular protein biosynthesis and are major components of ribosomes. Canonically, they are involved in the complex system of ribosome biogenesis pivotal to the catalysis of protein ...
Edmund Ui-Hang Sim +2 more
doaj +1 more source
Truncation of the Mrp20 Protein Reveals New Ribosome‐assembly Subcomplex in Mitochondria [PDF]
Mitochondrial ribosomal protein 20 (Mrp20) is a component of the yeast mitochondrial large (54S) ribosomal subunit and is homologous to the bacterial L23 protein, located at the ribosomal tunnel exit site.
Kaur, Jasvinder, Stuart, Rosemary A.
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The SILVA ribosomal RNA gene database project: improved data processing and web-based tools
SILVA (from Latin silva, forest, http://www.arb-silva.de) is a comprehensive web resource for up to date, quality-controlled databases of aligned ribosomal RNA (rRNA) gene sequences from the Bacteria, Archaea and Eukaryota domains and supplementary ...
Christian Quast +7 more
semanticscholar +1 more source
Nuclear Export of Pre-Ribosomal Subunits Requires Dbp5, but Not as an RNA-Helicase as for mRNA Export. [PDF]
The DEAD-box RNA-helicase Dbp5/Rat8 is known for its function in nuclear mRNA export, where it displaces the export receptor Mex67 from the mRNA at the cytoplasmic side of the nuclear pore complex (NPC).
Bettina Neumann +3 more
doaj +1 more source
Duck hepatitis A virus 1 (DHAV-1) belongs to the genus Avihepatovirus in the family Picornaviridae. Little research has been carried out on the non-structural proteins of this virus.
Xiaoyao Yang +42 more
doaj +1 more source
A model for the study of ligand binding to the ribosomal RNA helix h44. [PDF]
Oligonucleotide models of ribosomal RNA domains are powerful tools to study the binding and molecular recognition of antibiotics that interfere with bacterial translation.
Dibrov, Sergey M +2 more
core +3 more sources

