Results 231 to 240 of about 699,944 (333)

THE CHROMOSOMAL SITE SPECIFYING A RIBOSOMAL PROTEIN IN ESCHERICHIA COLI [PDF]

, 1964
Phoebe S. Leboy, Edward C. Cox, Joel G. Flaks   +2 more
openalex   +1 more source

Novel Intragenic Duplication of GATAD2B in a Patient With GAND

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The nucleosome remodeling and deacetylation (NuRD) complex is a major chromatin regulator and plays a critical role in regulating gene transcription, genome integrity, and cell cycle progression. Heterozygous variants in GATAD2B, a core NuRD component, have been reported to cause GATAD2B‐Associated Neurodevelopmental Disorder (GAND), an ...
Mari Mori, Steven Estes, Swetha Ramadesikan, Betsy Schmalz, Shayne Plourde, Maria E. Hernandez Gonzalez, Anthony R. Miller, Bimal P. Chaudhari, Richard K. Wilson, Daniel C. Koboldt   +9 more
wiley   +1 more source

Titanium ions promote tomato growth and increase stress resistance. [PDF]

BMC Plant Biol
Ma YB, Li WL, Li JH, Li MJ, Li XY, Wei CM, Li CX, Wang Y, Zhao Y, Ma XR.   +9 more
europepmc   +1 more source

Studies on the Primary Structure of Ribosomal 28 S Ribonucleic Acid and Its Nucleolar Precursors

, 1969
Joan Wikman, Eugene F. Howard, Harris Busch   +2 more
openalex   +1 more source

Long noncoding RNA GCH1 mediates mitophagy via the PTEN‐induced kinase 1/Parkin pathway to drive chondrocyte dysfunction and cartilage degeneration in osteoarthritis

Animal Models and Experimental Medicine, EarlyView.
The graphical abstract illustrates the role of lncRNA‐GCH1 in regulating mitophagy and its downstream effects on chondrocyte dysfunction and cartilage degradation in osteoarthritis (OA). Elevated lncRNA‐GCH1 stabilizes PINK1 protein, enhancing mitophagy and mitochondrial turnover.
Gang Zeng, Yujun Sun, Taihe Liu, Wenzhou Liu, Yanbo Chen, Jionglin Wu, Jiayuan Zheng, Weidong Song, Yue Ding   +8 more
wiley   +1 more source

The Natural Redox Cofactor Pyrroloquinoline Quinone (PQQ) Enables Photocatalytic Radical Cyclizations

Angewandte Chemie, EarlyView.
Natural alcohol and sugar dehydrogenases that utilize the redox cofactor pyrroloquinoline quinone (PQQ) can be repurposed for enantioselective photoredox catalysis. Upon blue‐light irradiation, redox‐neutral radical cyclizations are catalyzed. This work adds a new class of enzymes to the toolbox of photobiocatalysis.
Srishti B. Bahukhandi, Andreas S. Klein, Ghulam Mustafa, Maria Weyh, Alexandra Walter, Erling Thyrhaug, Jürgen Hauer, Golo Storch, Cathleen Zeymer   +8 more
wiley   +2 more sources

Cryo-EM structure of ribosome from pathogenic protozoa Entamoeba histolytica reveals unique features of its architecture. [PDF]

Nat Commun
Sharma S, Mishra S, Gourinath S, Kaushal PS.   +3 more
europepmc   +1 more source

LOCALIZATION OF SENSITIVITY TO KANAMYCIN AND STREPTOMYCIN IN 30S RIBOSOMAL PROTEINS OF ESCHERICHIA COLI

, 1969
Hiroshi Masukawa
openalex   +2 more sources

The FindMNDBiomarker Program: Protein Changes in Motor Neuron Disease/Amyotrophic Lateral Sclerosis Postmortem Tissue and Biofluids

Annals of Neurology, EarlyView.
Objective Biomarkers of disease pathogenesis are critically needed for amyotrophic lateral sclerosis (ALS) to facilitate diagnosis and patient stratification into appropriate therapeutic trials. Proteomic studies offer significant potential to advance this, but reproducibility across laboratories is a key component toward identifying protein changes ...
Gabrielle L. Adler, Matthew C. Kiernan, Rachel H. Tan   +2 more
wiley   +1 more source

Structural Basis for a Scaffolding Role of the COM Domain in Nonribosomal Peptide Synthetases

Angewandte Chemie, EarlyView.
COM domains are known as docking domains between subunits of nonribosomal peptide synthetases (NRPSs). Here, the first structure of a fused, internal COM domain with its neighboring domains is reported. Structural, biochemical and crosslinking data show that COM domains play an unexpected role in properly positioning epimerization (E) and condensation (
Julia Diecker, Benedikt Hermanns, Jennifer Rüschenbaum, René Rasche, Wolfgang Dörner, Alexander Schröder, Daniel Kümmel, Henning D. Mootz   +7 more
wiley   +2 more sources