Results 241 to 250 of about 846,528 (387)

ALDOA‐Mediated Metabolic Reprogramming is a Targetable Vulnerability for Ferroptosis Sensitization in Cancer

Advanced Science, EarlyView.
ALDOA‐depletion‐mediated glycolytic reprogramming promotes autophagy‐mediated degradation of MBOAT2, increasing the ratio of phospholipids containing pro‐ferroptotic polyunsaturated fatty acids over anti‐ferroptotic monounsaturated fatty acids, and thus sensitizing cancer cells to ferroptosis.
Pengqi Wang, Kezhang He, Bowen Wang, Wei Zhou, Ying Zhang, Tianhua Ma, Sheng Ding   +6 more
wiley   +1 more source

Proteomic signatures and mitochondrial dysfunctions in peripheral T cells reveal novel ınsights into Alzheimer's disease. [PDF]

Sci Rep
Koca S, Kiris I, Sahin S, Karsidag S, Cinar N, Baykal AT.   +5 more
europepmc   +1 more source

A novel function for the 90 kDa heat-shock protein (Hsp90): facilitating nuclear export of 60 S ribosomal subunits [PDF]

, 2002
Harald Schlatter, Thomas Langer, Susann Rosmus, Marie-Luise ONNEKEN, H. Fasold   +4 more
openalex   +1 more source

Multi‐Omics Reveal the Dysregulated Gut‐Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China

Advanced Science, EarlyView.
The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang, Yi Liu, Ziying Sun, Jia Li, Zhihao Lu, Jiayuan Huang, Shixian Hu, Peihua Cao, Xiaolong Cao, Shangru Li, Jianzhao Ruan, Jinhui Liu, Jingyu Xie, Haitao Sun, Tianyu Chen, Shengfa Li, Zhaohua Zhu, Zhibo Wen, Rocky S. Tuan, David John Hunter, Zhong Alan Li, Dongquan Shi, Changhai Ding   +22 more
wiley   +1 more source

<i>In vivo</i> development of elevated linezolid resistance mediated by a deletion in ribosomal protein L3 in clinical <i>Enterococcus faecium</i>. [PDF]

Antimicrob Agents Chemother
Sun L, Lei T, Liu Y, Lu S, Hua X, Zhang J, Chen Y.   +6 more
europepmc   +1 more source

25 years of serving the community with ribosomal RNA gene reference databases and tools.

Journal of Biotechnology, 2017
F. Glöckner, Pelin Yilmaz, Christian Quast, Jan Gerken, A. Beccati, Andreea Ciuprina, Gerrit Bruns, P. Yarza, J. Peplies, Ralf Westram, W. Ludwig   +10 more
semanticscholar   +1 more source

Payload‐Driven Design of Polymeric Carriers for Nucleic Acid Delivery: Insights from Structure–Function Relationships

Advanced Science, EarlyView.
Polymeric carriers provide versatile platforms for nucleic acid delivery. This review introduces a novel perspective inspired by protein structural organization to explore structure–function relationships of polymeric carriers, highlighting requirements of different nucleic acid payloads.
Hanieh Moradian, Charlotte Maeve Dunne, Manfred Gossen, Matthias Hartlieb   +3 more
wiley   +1 more source

From Bioinformatic Modeling to Clinical Observation: Potential Implications of Ribosomal RNA Folding in <i>Blastocystis</i> sp. Isolates from Symptomatic and Asymptomatic Carriers. [PDF]

Pathogens
Martínez-Hernández F, Martínez A, Zampedri C, Romero-Valdovinos M, Jiménez-Gutiérrez C, Flores-Martínez K, Trejo-Chávez A, Villalobos G, Maravilla P.   +8 more
europepmc   +1 more source

X‐ray crystallography study on ribosome recycling: the mechanism of binding and action of RRF on the 50S ribosomal subunit

, 2004
Daniel N. Wilson, Frank Schluenzen, Joerg Harms, Takuya Yoshida, Tadayasu Ohkubo, Renate Albrecht, J. Buerger, Yuji Kobayashi, Paola Fucini   +8 more
openalex   +1 more source

MOLECULAR DIFFERENTIATION OF COLONIZED HUMAN MALARIA VECTORS BY 28S RIBOSOMAL DNA POLYMORPHISMS [PDF]

, 2004
Rebekah J. Kent, Adrian K. West, Douglas E. Norris   +2 more
openalex   +1 more source