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Crystallization of Ribosomes, Ribosomal Subunits, and Individual Ribosomal Proteins
1991There is interest in the three-dimensional structure of the ribosome since it is a unique multicomponent biological system responsible for the biosynthesis of protein in the cell. The exceedingly complex structure of ribosomes (for example, the Escherichia coli ribosome, the molecular weight of which is 2.15•106 Da, consists of three types of RNA and ...
B. K. Vainshtein, S. D. Trakhanov
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Orthogonal Ribosome Biofirewall
ACS Synthetic Biology, 2017Biocontainment systems are crucial for preventing genetically modified organisms from escaping into natural ecosystems. Here, we describe the orthogonal ribosome biofirewall, which consists of an activation circuit and a degradation circuit. The activation circuit is a genetic AND gate based on activation of the encrypted pathway by the orthogonal ...
Bin Jia +7 more
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Ribosome-inactivating proteins
Toxicon, 1997Abstract Ribosome-inactivating proteins (RIPs, review by Barbieri et a/. 1993) are a class of proteins present in various tissues of several plants which inactivate mammalian ribosomes and, with less activity and to variable extent, plant, fungal, and bacterial ribosomes. They are enzymes, N-glycosidases, which release adenine from rRNA.
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Ribosomal RNA on the Surface of Ribosomes
Science, 1963Ribonuclease from pancreas releases nucleotide from Escherichia coli ribosomes while not altering significantly the base composition of the total ribosomal RNA. Ribonuclease hydrolyzes ribsomal RNA without destroying the structure of 70 S or 30 S and 50 S
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