Results 101 to 110 of about 59,620 (205)
Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania. [PDF]
Knowledge of viral diversity is expanding greatly, but many lineages remain underexplored. We surveyed RNA viruses in 52 cultured monoxenous relatives of the human parasite <i>Leishmania</i> ( <i>Crithidia</i> and <i> ...
Akopyants, N.S. +19 more
core +1 more source
Web Service for Finding Ribosomal Frameshifts [PDF]
Recent advances in biomedical research have generated a huge amount of data and software to deal with the data. Many biomedical systems use heterogeneous data structures and incompatible software components, so integration of software components into a system can be hindered by incompatibilities between the components of the system. This paper presents
Yanga Byun, Sanghoon Moon, Kyungsook Han
openaire +1 more source
Discovery of frameshifting in Alphavirus 6K resolves a 20-year enigma
Background The genus Alphavirus includes several potentially lethal human viruses. Additionally, species such as Sindbis virus and Semliki Forest virus are important vectors for gene therapy, vaccination and cancer research, and important models for ...
Fleeton Marina N +3 more
doaj +1 more source
High-Resolution Analysis of Coronavirus Gene Expression by RNA Sequencing and Ribosome Profiling. [PDF]
Members of the family Coronaviridae have the largest genomes of all RNA viruses, typically in the region of 30 kilobases. Several coronaviruses, such as Severe acute respiratory syndrome-related coronavirus (SARS-CoV) and Middle East respiratory syndrome-
Brierley, Ian +5 more
core +3 more sources
ABSTRACT Phylogenomics is a transformative approach in systematics, conservation biology, and biomedical research, enabling the inference of evolutionary relationships by leveraging hundreds to thousands of genes from genomic or transcriptomic data. However, acquiring high‐quality genomes and transcriptomes necessitates samples with intact DNA and RNA,
Yunlong Li +5 more
wiley +1 more source
Thermodynamic stability of recoding RNA pseudoknots and ribosomal frameshifting [PDF]
Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to digital@library.tamu.edu, referencing the URI of the ...
Cannon, Brian Ray
core
Ribosomes slide on lysine-encoding homopolymeric A stretches. [PDF]
Protein output from synonymous codons is thought to be equivalent if appropriate tRNAs are sufficiently abundant. Here we show that mRNAs encoding iterated lysine codons, AAA or AAG, differentially impact protein synthesis: insertion of iterated AAA ...
Brunelle, Julie L +5 more
core +3 more sources
Summary Inherited bone marrow failure syndromes (IBMFSs) are genetically heterogeneous with an expanding spectrum of causative genes. Recent molecular advances are thought to have contributed to genetic identification, yet the true gain in diagnostic yield remains unclear.
Ye Jee Shim +21 more
wiley +1 more source
The mitochondrial genome of the hexactinellid sponge : Evidence for programmed translational frameshifting [PDF]
Background Mitochondrial genomes (mtDNA) of numerous sponges have been sequenced as part of an ongoing effort to resolve the class-level phylogeny of the Porifera, as well as to place the various lower metazoan groups on the animal-kingdom tree.
Leys Sally P +4 more
core +1 more source
Intricacies of ribosomal frameshifting
Folded structures in mRNAs can stimulate reprogramming of ribosomes to make one protein from two different reading frames. The first crystal structure of a frameshift stimulatory RNA pseudoknot reveals remarkable features.
Atkins, John F., Gesteland, Raymond F.
openaire +1 more source

