Results 151 to 160 of about 5,829,574 (377)

Ribosome inactivating proteins and apoptosis

open access: yesFEBS Letters, 2005
Ribosome inactivating proteins (RIPs) are protein toxins that are of plant or microbial origin that inhibit protein synthesis by inactivating ribosomes. Recent studies suggest that RIPs are also capable of inducing cell death by apoptosis. Though many reports are available on cell death induced by RIPs, the mechanism involved is not well studied ...
Narayanan, Sriram   +4 more
openaire   +3 more sources

Pupylation‐Based Proximity Labeling Unravels a Comprehensive Protein and Phosphoprotein Interactome of the Arabidopsis TOR Complex

open access: yesAdvanced Science, EarlyView.
The target of rapamycin (TOR) complex is a central plant growth regulator. Here, the protein–protein interactions underlying its various functions are mapped by pupylation‐based proximity‐labeling in Arabidopsis, using TOR complex subunits LST8‐1 and RAPTOR1, alongside TOR inhibitor FK506‐binding protein, as baits.
Shuai Zheng   +9 more
wiley   +1 more source

Dual‐Gating Strategy: Ultrasound Activation of TRPV2 Channels and Borate‐Glass‐Induced Calcium Overload for Tumor Suppression

open access: yesAdvanced Science, EarlyView.
A novel strategy combining borate glass and ultrasound is proposed for the precise treatment of breast cancer. The locally delivered borate glass releases Ca2⁺ ions in situ, while ultrasound activates the highly expressed transient receptor potential vanilloid 2 channels in breast cancer cells. This synergistic effect induces specific calcium overload,
Haihong Zhu   +10 more
wiley   +1 more source

Ribosome Flow Model with Extended Objects [PDF]

open access: yesarXiv, 2017
We study a deterministic mechanistic model for the flow of ribosomes along the mRNA molecule, called the ribosome flow model with extended objects (RFMEO). This model encapsulates many realistic features of translation including non-homogeneous transition rates along the mRNA, the fact that every ribosome covers several codons, and the fact that ...
arxiv  

Revised Classification Scheme of Phytoplasmas based on RFLP Analyses of 16S rRNA and Ribosomal Protein Gene Sequences

open access: yes, 1998
RFLP analyses of 16S rDNA nested PCR products from 34 phytoplasma strains with 17 restriction enzymes delineated distinct pattern types. Based on similarity coefficients derived from RFLP analyses, the 34 representative phytoplasma strains were ...
Ing-Ming Lee   +3 more
semanticscholar   +1 more source

Lactobacillus johnsonii Generates Cyclo(pro‐trp) and Promotes Intestinal Ca2+ Absorption to Alleviate CKD–SHPT

open access: yesAdvanced Science, EarlyView.
The mechanism map of how L.johnsonii generates cyclo(pro‐trp) to alleviate CKD–SHPT by promoting the expression of CaSR and TRPV4 in IECs, enhancing Ca2+ absorption, and negatively feedback inhibiting iPTH secretion. Abstract Patients with chronic kidney disease (CKD) are at a high risk of developing secondary hyperparathyroidism (SHPT), which may ...
Xiong Zeng   +13 more
wiley   +1 more source

Performance of VITEK mass spectrometry V3.0 for rapid identification of clinical Aspergillus fumigatus in different culture conditions based on ribosomal proteins

open access: yesInfection and Drug Resistance, 2017
Longrong Zhou, Yongquan Chen, Yuanhong Xu Department of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Anhui, Hefei, People’s Republic of China Abstract: Fast and accurate discrimination of Aspergillus ...
Zhou L, Chen Y, Xu Y
doaj  

Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.

open access: yesBlood, 2011
Diamond-Blackfan anemia (DBA) is a congenital erythroid hypoplasia caused by a functional haploinsufficiency of genes encoding for ribosomal proteins. Among these genes, ribosomal protein S19 (RPS19) is mutated most frequently.
P. Jaako   +12 more
semanticscholar   +1 more source

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