Results 191 to 200 of about 540,233 (304)
This study explores the origins of life by linking prebiotic chemistry, the emergence of information‐carrying molecules such as RNA and proteins, and philosophical questions about consciousness. The study emphasizes the role of molecular evolution in the Central Dogma and provides insights into the chemical origins of biology and the basis of life's ...
Harald Schwalbe +5 more
wiley +2 more sources
Loss of ribosomal protein uL14 enables tumor escape from T cell immunosurveillance. [PDF]
Dopler A +13 more
europepmc +1 more source
Programmable RNA N6,2´‐O‐Dimethyladenosine Editing
ABSTRACT N6,2’‐O‐dimethyladenosine (m6Am) is a prevalent RNA modification located at the first transcribed nucleotide adjacent to the 5′ cap of mRNAs, where it has been implicated in gene regulation. However, the lack of methods for precise, transcript‐specific manipulation of m6Am has limited its functional dissection.
Yang Li +9 more
wiley +1 more source
Uncovering Cystic Fibrosis Carrier: Insights From a Heterozygous CFTR‐F508del Rabbit Model
ABSTRACT Background Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disorder frequently associated with impaired mucociliary clearance and bacterial infection. Individuals carrying a single cystic fibrosis transmembrane conductance regulator (CFTR) mutation exhibit partial CFTR dysfunction and are increasingly recognized as being at risk ...
Do‐Yeon Cho +9 more
wiley +1 more source
Exploring mitochondrial ribosomal protein S12 as a novel target for non-small cell lung cancer. [PDF]
Chen Z, Jin Y, Wei S, Wei R, Ding X.
europepmc +1 more source
Objective Biallelic variants in PRKN cause autosomal recessive Parkinson's disease (PD) with a median age at onset of 31 years. When evaluating the 16 previously published carriers of a homozygous deletion of Exon 2 from the International Parkinson's Disease and Movement Disorder Society Gene Database (MDSGene) database, the median age at onset is ...
Arian Hach +14 more
wiley +1 more source
Publisher Correction: Expressions, immune associations, and prognostic values of mitochondrial ribosomal protein MRPL3 in the Pan cancer landscape. [PDF]
Lin J, Chen W, Zhao Y, Qiu G.
europepmc +1 more source
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari +5 more
wiley +1 more source
Expressions, immune associations, and prognostic values of mitochondrial ribosomal protein MRPL3 in the pan cancer landscape. [PDF]
Lin J, Chen W, Zhao Y, Qiu G.
europepmc +1 more source
Stripping of ribosomal proteins from Escherichia coli ribosomes [PDF]
Spitnik-Elson, P., Atsmon, A.
openaire +2 more sources

