Results 41 to 50 of about 5,829,574 (377)
Frontiers in Plant Science, 2016 Protein translation is an energy consuming process that has to be fine-tuned at both the cell and organism levels to match the availability of resources.
Thomas Dobrenel +13 more
semanticscholar +1 more source
Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation
Nature Communications, 2016 Eukaryotic ribosomes assemble by association of ribosomal RNA with ribosomal proteins into nuclear precursor particles, which undergo a complex maturation pathway coordinated by non-ribosomal assembly factors.
Valentin Mitterer +9 more
semanticscholar +1 more source
Alterations in the ribosomal machinery in cancer and hematologic disorders
Journal of Hematology & Oncology, 2012 Ribosomes are essential components of the protein translation machinery and are composed of more than 80 unique large and small ribosomal proteins. Recent studies show that in addition to their roles in protein translation, ribosomal proteins are also ...
Shenoy Niraj +6 more
doaj +1 more source
Protein escape at the ribosomal exit tunnel: Effect of the tunnel shape [PDF]
J. Chem. Phys. 153, 045105 (2020), 2020 We study the post-translational escape of nascent proteins at the ribosomal exit tunnel with the consideration of a real shape atomistic tunnel based on the Protein Data Bank (PDB) structure of the large ribosome subunit of archeon Haloarcula marismortui.
arxiv +1 more source
The Evolution of the Ribosomal Protein-MDM2-p53 Pathway.
Cold Spring Harbor Perspectives in Medicine, 2016 The progression of our understanding of ribosomal proteins as static building blocks of the ribosome to highly integrated sensors of p53 surveillance and function has achieved a tremendous rate of growth over the past several decades. As the workhorse of
C. Deisenroth +2 more
semanticscholar +1 more source
Journal of Extracellular Biology, 2022 MET receptor tyrosine kinase is a cell surface receptor that plays important role in embryonic development and tissue regeneration. Aberrant MET activation has been widely reported in different human cancers, making MET an attractive therapeutic target ...
Sze Keong Tey +6 more
doaj +1 more source
Nucleic Acids Research, 2016 Most budding yeast introns exist in the many duplicated ribosomal protein genes (RPGs) and it has been posited that they remain there to modulate the expression of RPGs and cell growth in response to stress.
Cyrielle Petibon +3 more
semanticscholar +1 more source
Ribosomal Protein S6 Phosphorylation in the Nervous System: From Regulation to Function
Frontiers in Molecular Neuroscience, 2015 Since the discovery of the phosphorylation of the 40S ribosomal protein S6 (rpS6) about four decades ago, much effort has been made to uncover the molecular mechanisms underlying the regulation of this post-translational modification.
Anne Biever, E. Valjent, E. Puighermanal
semanticscholar +1 more source
Ribosome-Inactivating and Related Proteins [PDF]
Toxins, 2015 Ribosome-inactivating proteins (RIPs) are toxins that act as N-glycosidases (EC 3.2.2.22). They are mainly produced by plants and classified as type 1 RIPs and type 2 RIPs. There are also RIPs and RIP related proteins that cannot be grouped into the classical type 1 and type 2 RIPs because of their different sizes, structures or functions. In addition,
Schrot, Joachim +2 more
openaire +5 more sources
Distribution of dwell times of a ribosome: effects of infidelity, kinetic proofreading and ribosome crowding [PDF]
Physical Biology, 8 (2011) 026005, 2010 Ribosome is a molecular machine that polymerizes a protein where the sequence of the amino acid residues, the monomers of the protein, is dictated by the sequence of codons (triplets of nucleotides) on a messenger RNA (mRNA) that serves as the template. The ribosome is a molecular motor that utilizes the template mRNA strand also as the track. Thus, in
arxiv +1 more source