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Ribosomal Proteins in Ribosome Assembly [PDF]
BiomoleculesRibosomes are the cellular machinery responsible for translating mRNA into proteins, a process fundamental to all domains of life from bacteria to eukaryotes [...]
Brigitte Pertschy, Ingrid Zierler
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Phylogenomics of prokaryotic ribosomal proteins. [PDF]
PLoS ONE, 2012 Archaeal and bacterial ribosomes contain more than 50 proteins, including 34 that are universally conserved in the three domains of cellular life (bacteria, archaea, and eukaryotes).
Natalya Yutin +3 more
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Mitochondrial Ribosomal Proteins and Cancer [PDF]
MedicinaMitochondria play key roles in maintaining cell life and cell function, and their dysfunction can lead to cell damage. Mitochondrial ribosomal proteins (MRPs) are encoded by nuclear genes and are assembled within the mitochondria.
Huiyi Wu +5 more
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Ribosomes: The New Role of Ribosomal Proteins as Natural Antimicrobials. [PDF]
Int J Mol Sci, 2022 Moonlighting proteins are those capable of performing more than one biochemical or biophysical function within the same polypeptide chain. They have been a recent focus of research due to their potential applications in the health, pharmacological, and ...
Hurtado-Rios JJ +3 more
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Regulation of Ribosomal Proteins on Viral Infection
Cells, 2019 Ribosomal proteins (RPs), in conjunction with rRNA, are major components of ribosomes involved in the cellular process of protein biosynthesis, known as “translation”.
Shuo Li
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Extraribosomal Functions of Cytosolic Ribosomal Proteins in Plants
Frontiers in Plant Science, 2021 Ribosomes are basic translational machines in all living cells. The plant cytosolic ribosome is composed of four rRNAs and approximately 81 ribosomal proteins (RPs). In addition to the fundamental functions of RPs in the messenger RNA decoding process as
Wei Xiong +4 more
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Differential Stoichiometry among Core Ribosomal Proteins [PDF]
Cell Reports, 2015 Understanding the regulation and structure of ribosomes is essential to understanding protein synthesis and its dysregulation in disease. While ribosomes are believed to have a fixed stoichiometry among their core ribosomal proteins (RPs), some ...
Nikolai Slavov +4 more
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Ribosomal proteins produced in excess are degraded by the ubiquitin-proteasome system [PDF]
Molecular Biology of the Cell, 2016 Ribosome assembly is an essential process that consumes prodigious quantities of cellular resources. Ribosomal proteins cannot be overproduced in Saccharomyces cerevisiae because the excess proteins are rapidly degraded.
Deshaies, Raymond J. +4 more
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Archaea/eukaryote-specific ribosomal proteins - guardians of a complex structure [PDF]
Computational and Structural Biotechnology Journal, 2023 In three domains of life, proteins are synthesized by large ribonucleoprotein particles called ribosomes. All ribosomes are composed of ribosomal RNAs (rRNA) and numerous ribosomal proteins (r-protein).
Ivan Kisly, Tiina Tamm
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The Influence of Extra-Ribosomal Functions of Eukaryotic Ribosomal Proteins on Viral Infection [PDF]
BiomoleculesThe eukaryotic ribosome is a large ribonucleoprotein complex consisting of four types of ribosomal RNA (rRNA) and approximately 80 ribosomal proteins (RPs), forming the 40S and 60S subunits.
Zhongwei Zhao +8 more
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