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Ribosomal Proteins in Ribosome Assembly [PDF]

Biomolecules
Ribosomes are the cellular machinery responsible for translating mRNA into proteins, a process fundamental to all domains of life from bacteria to eukaryotes [...]
Brigitte Pertschy, Ingrid Zierler
doaj   +4 more sources

Mitochondrial Ribosomal Proteins and Cancer [PDF]

Medicina
Mitochondria play key roles in maintaining cell life and cell function, and their dysfunction can lead to cell damage. Mitochondrial ribosomal proteins (MRPs) are encoded by nuclear genes and are assembled within the mitochondria.
Huiyi Wu, Xiaowei Zhu, Huilin Zhou, Min Sha, Jun Ye, Hong Yu   +5 more
doaj   +4 more sources

Phylogenomics of prokaryotic ribosomal proteins. [PDF]

PLoS ONE, 2012
Archaeal and bacterial ribosomes contain more than 50 proteins, including 34 that are universally conserved in the three domains of cellular life (bacteria, archaea, and eukaryotes).
Natalya Yutin, Pere Puigbò, Eugene V Koonin, Yuri I Wolf   +3 more
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Archaea/eukaryote-specific ribosomal proteins - guardians of a complex structure [PDF]

Computational and Structural Biotechnology Journal, 2023
In three domains of life, proteins are synthesized by large ribonucleoprotein particles called ribosomes. All ribosomes are composed of ribosomal RNAs (rRNA) and numerous ribosomal proteins (r-protein).
Ivan Kisly, Tiina Tamm
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The Influence of Extra-Ribosomal Functions of Eukaryotic Ribosomal Proteins on Viral Infection [PDF]

Biomolecules
The eukaryotic ribosome is a large ribonucleoprotein complex consisting of four types of ribosomal RNA (rRNA) and approximately 80 ribosomal proteins (RPs), forming the 40S and 60S subunits.
Zhongwei Zhao, Shan Ruan, Yang Li, Te Qi, Ying Qi, Yujing Huang, Zhongyang Liu, Qiang Ruan, Yanping Ma   +8 more
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Ribosomal proteins in hepatocellular carcinoma: mysterious but promising [PDF]

Cell & Bioscience
Ribosomal proteins (RPs) are essential components of ribosomes, playing a role not only in ribosome biosynthesis, but also in various extra-ribosomal functions, some of which are implicated in the development of different types of tumors.
Qian Su, Huizhen Sun, Ling Mei, Ying Yan, Huimin Ji, Le Chang, Lunan Wang   +6 more
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Proteomics shows that brain metastases of lung adenocarcinoma overexpress ribosomal proteins in response to gamma knife radiosurgery [PDF]

Scientific Reports
Gamma knife radiosurgery (GKRS) is recommended as the first-line treatment for brain metastases of lung adenocarcinoma (LUAD) in many guidelines, but its specific mechanism is unclear.
Luqing Tong, Ke Ye, Qun Chen, Xiaoxi Wang, Chi Hu, Qingsheng Xu, Lihui Zhou, Renya Zhan, Ying Tong   +8 more
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Roles of ribosomal proteins in hematologic disorders and cancers: a review

Emergency and Critical Care Medicine, 2023
. Ribosomes are important organelles for synthesizing proteins in cells. They are composed of ribosomal RNA and more than 80 ribosomal proteins. It is well known that an essential function of ribosomal proteins is to participate in protein translation ...
Jie Wang, Feng Yan
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Ribosomal proteins: mutant phenotypes by the numbers and associated gene expression changes [PDF]

Open Biology, 2020
Ribosomal proteins are highly conserved, many universally so among organisms. All ribosomal proteins are structural parts of the same molecular machine, the ribosome.
Michael Polymenis
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The roles of ribosomal proteins in nasopharyngeal cancer: culprits, sentinels or both

Biomarker Research, 2021
Ribosomal protein genes encode products that are essential for cellular protein biosynthesis and are major components of ribosomes. Canonically, they are involved in the complex system of ribosome biogenesis pivotal to the catalysis of protein ...
Edmund Ui-Hang Sim, Choon-Weng Lee, Kumaran Narayanan   +2 more
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