Results 1 to 10 of about 5,783,806 (229)

Differential Stoichiometry among Core Ribosomal Proteins [PDF]

Cell Reports, 2015
Understanding the regulation and structure of ribosomes is essential to understanding protein synthesis and its dysregulation in disease. While ribosomes are believed to have a fixed stoichiometry among their core ribosomal proteins (RPs), some ...
Nikolai Slavov, Stefan Semrau, Edoardo Airoldi, Bogdan Budnik, Alexander van Oudenaarden   +4 more
doaj   +4 more sources

Ribosomes: The New Role of Ribosomal Proteins as Natural Antimicrobials. [PDF]

Int J Mol Sci, 2022
Moonlighting proteins are those capable of performing more than one biochemical or biophysical function within the same polypeptide chain. They have been a recent focus of research due to their potential applications in the health, pharmacological, and ...
Hurtado-Rios JJ, Carrasco-Navarro U, Almanza-Pérez JC, Ponce-Alquicira E.   +3 more
europepmc   +2 more sources

Ribosomal Proteins in Ribosome Assembly [PDF]

Biomolecules
Ribosomes are the cellular machinery responsible for translating mRNA into proteins, a process fundamental to all domains of life from bacteria to eukaryotes [...]
Brigitte Pertschy, Ingrid Zierler
doaj   +2 more sources

Mitochondrial Ribosomal Proteins and Cancer [PDF]

Medicina
Mitochondria play key roles in maintaining cell life and cell function, and their dysfunction can lead to cell damage. Mitochondrial ribosomal proteins (MRPs) are encoded by nuclear genes and are assembled within the mitochondria.
Huiyi Wu, Xiaowei Zhu, Huilin Zhou, Min Sha, Jun Ye, Hong Yu   +5 more
doaj   +2 more sources

Deregulation of ribosomal proteins in human cancers. [PDF]

Biosci Rep, 2021
The ribosome, the site for protein synthesis, is composed of ribosomal RNAs (rRNAs) and ribosomal proteins (RPs). The latter have been shown to have many ribosomal and extraribosomal functions.
El Khoury W, Nasr Z.
europepmc   +2 more sources

Phylogenomics of prokaryotic ribosomal proteins. [PDF]

PLoS ONE, 2012
Archaeal and bacterial ribosomes contain more than 50 proteins, including 34 that are universally conserved in the three domains of cellular life (bacteria, archaea, and eukaryotes).
Natalya Yutin, Pere Puigbò, Eugene V Koonin, Yuri I Wolf   +3 more
doaj   +2 more sources

Regulation of Ribosomal Proteins on Viral Infection

Cells, 2019
Ribosomal proteins (RPs), in conjunction with rRNA, are major components of ribosomes involved in the cellular process of protein biosynthesis, known as “translation”.
Shuo Li
doaj   +2 more sources

The Influence of Extra-Ribosomal Functions of Eukaryotic Ribosomal Proteins on Viral Infection [PDF]

Biomolecules
The eukaryotic ribosome is a large ribonucleoprotein complex consisting of four types of ribosomal RNA (rRNA) and approximately 80 ribosomal proteins (RPs), forming the 40S and 60S subunits.
Zhongwei Zhao, Shan Ruan, Yang Li, Te Qi, Ying Qi, Yujing Huang, Zhongyang Liu, Qiang Ruan, Yanping Ma   +8 more
doaj   +2 more sources

Studies on the assembly characteristics of large subunit ribosomal proteins in S. cerevisae. [PDF]

PLoS ONE, 2013
During the assembly process of ribosomal subunits, their structural components, the ribosomal RNAs (rRNAs) and the ribosomal proteins (r-proteins) have to join together in a highly dynamic and defined manner to enable the efficient formation of ...
Uli Ohmayer, Michael Gamalinda, Martina Sauert, Julius Ossowski, Gisela Pöll, Jan Linnemann, Thomas Hierlmeier, Jorge Perez-Fernandez, Beril Kumcuoglu, Isabelle Leger-Silvestre, Marlène Faubladier, Joachim Griesenbeck, John Woolford, Herbert Tschochner, Philipp Milkereit   +14 more
doaj   +2 more sources

Archaea/eukaryote-specific ribosomal proteins - guardians of a complex structure [PDF]

Computational and Structural Biotechnology Journal, 2023
In three domains of life, proteins are synthesized by large ribonucleoprotein particles called ribosomes. All ribosomes are composed of ribosomal RNAs (rRNA) and numerous ribosomal proteins (r-protein).
Ivan Kisly, Tiina Tamm
doaj   +2 more sources