Results 91 to 100 of about 5,783,905 (321)

Piezo1 channels enhance anabolic signaling activation induced by electrical stimulation of cultured myotubes

open access: yesFEBS Open Bio, EarlyView.
By using an electrical pulse stimulation (EPS)‐based in vitro exercise model and chemical activation/inhibition of mechanosensitive Piezo1 channels, we explored changes in protein synthetic response in cultured C2C12 myotubes. Our data showed that application of Piezo1 activator (Yoda1) during EPS significantly enhances the rate of protein synthesis in
Natalia A. Vilchinskaya   +3 more
wiley   +1 more source

Genes involved in translation of Mycoplasma hyopneumoniae and Mycoplasma synoviae

open access: yesGenetics and Molecular Biology, 2007
This is a report on the analysis of genes involved in translation of the complete genomes of Mycoplasma hyopneumoniae strain J and 7448 and Mycoplasma synoviae.
Mônica de Oliveira Santos   +3 more
doaj   +1 more source

Molecular interactions between the constituents of small ribosomal subunit [PDF]

open access: yesarXiv, 2012
Availability of high-resolution crystal structures of ribosomal subunits of different species opens a route to investigate about molecular interactions between its constituents and stabilization strategy. Structural analysis of the small ribosomal subunit shows that primary binder proteins are mainly employed in stabilizing the folded ribosomal RNA by ...
arxiv  

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Optimal control of ribosome population for gene expression under periodic nutrient intake [PDF]

open access: yesJ. R. Soc. Interface. 2120230652
Translation of proteins is a fundamental part of gene expression that is mediated by ribosomes. As ribosomes significantly contribute to both cellular mass and energy consumption, achieving efficient management of the ribosome population is also crucial to metabolism and growth.
arxiv   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Strukturaufklärung, Totalsynthese, In‐Vivo‐Aktivität und Potentieller Biosyntheseweg des Neuen Myxobakteriellen Antibiotikums Corramycin**

open access: yesAngewandte Chemie, Volume 134, Issue 51, December 19, 2022., 2022
Corramycin ist ein neuer Naturstoff, welcher von dem Myxobakterium Corallococcus coralloides produziert wird. Seine Struktur sowie die außergewöhnliche Total‐ und Biosynthese des Antibiotikums werden hier zum ersten Mal beschrieben. Corramycin zeigt keine Zytotoxizität und keine Kreuzresistenz mit gängigen Antibiotikaklassen.
Cédric Couturier   +32 more
wiley   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

open access: yesAdvanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

Purification of 70S Ribosomes from Bacillus subtilis

open access: yesBio-Protocol, 2015
The eubacterial ribosome (70S) is a macromolecular complex that is composed of a small (30S) subunit and a large (50S) subunit. The small subunit comprises the 16S ribosomal RNA (rRNA) and more than 20 ribosomal proteins (r-proteins), whereas the large ...
Shota Suzuki   +2 more
doaj   +1 more source

Multifunctional Hydroxyapatite Coated with Gallium Liquid Metal‐Based Silver Nanoparticles for Infection Prevention and Bone Regeneration

open access: yesAdvanced Functional Materials, EarlyView.
A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen   +17 more
wiley   +1 more source

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