Results 11 to 20 of about 421,073 (317)
Proteomics shows that brain metastases of lung adenocarcinoma overexpress ribosomal proteins in response to gamma knife radiosurgery [PDF]
Scientific ReportsGamma knife radiosurgery (GKRS) is recommended as the first-line treatment for brain metastases of lung adenocarcinoma (LUAD) in many guidelines, but its specific mechanism is unclear.
Luqing Tong +8 more
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Ribosome Biogenesis and Cancer: Overview on Ribosomal Proteins [PDF]
International Journal of Molecular Sciences, 2021 Cytosolic ribosomes (cytoribosomes) are macromolecular ribonucleoprotein complexes that are assembled from ribosomal RNA and ribosomal proteins, which are essential for protein biosynthesis. Mitochondrial ribosomes (mitoribosomes) perform translation of the proteins essential for the oxidative phosphorylation system. The biogenesis of cytoribosomes and
Pecoraro Annalisa +3 more
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Roles of ribosomal proteins in hematologic disorders and cancers: a review
Emergency and Critical Care Medicine, 2023 . Ribosomes are important organelles for synthesizing proteins in cells. They are composed of ribosomal RNA and more than 80 ribosomal proteins. It is well known that an essential function of ribosomal proteins is to participate in protein translation ...
Jie Wang, Feng Yan
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Ribosomal proteins: mutant phenotypes by the numbers and associated gene expression changes [PDF]
Open Biology, 2020 Ribosomal proteins are highly conserved, many universally so among organisms. All ribosomal proteins are structural parts of the same molecular machine, the ribosome.
Michael Polymenis
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The roles of ribosomal proteins in nasopharyngeal cancer: culprits, sentinels or both
Biomarker Research, 2021 Ribosomal protein genes encode products that are essential for cellular protein biosynthesis and are major components of ribosomes. Canonically, they are involved in the complex system of ribosome biogenesis pivotal to the catalysis of protein ...
Edmund Ui-Hang Sim +2 more
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The Modular Adaptive Ribosome. [PDF]
PLoS ONE, 2016 The ribosome is an ancient machine, performing the same function across organisms. Although functionally unitary, recent experiments suggest specialized roles for some ribosomal proteins.
Anupama Yadav +5 more
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Ribosomal proteins: functions beyond the ribosome [PDF]
Journal of Molecular Cell Biology, 2015 Although ribosomal proteins are known for playing an essential role in ribosome assembly and protein translation, their ribosome-independent functions have also been greatly appreciated. Over the past decade, more than a dozen of ribosomal proteins have been found to activate the tumor suppressor p53 pathway in response to ribosomal stress. In addition,
Peng Liao +4 more
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Cotranslational Folding of Proteins on the Ribosome [PDF]
Biomolecules, 2020 Many proteins in the cell fold cotranslationally within the restricted space of the polypeptide exit tunnel or at the surface of the ribosome. A growing body of evidence suggests that the ribosome can alter the folding trajectory in many different ways. In this review, we summarize the recent examples of how translation affects folding of single-domain,
Marija Liutkute +2 more
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Tagging of RPS9 as a tool for ribosome purification and identification of ribosome-associated proteins [PDF]
Archives of Biological Sciences, 2021 Ribosomes, the catalytic machinery required for protein synthesis, are comprised of 4 ribosomal RNAs and about 80 ribosomal proteins in mammals. Ribosomes further interact with numerous associated factors that regulate their biogenesis and function.
Jovanović Bogdan +3 more
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Evolution of Ribosomal Proteins [PDF]
European Journal of Biochemistry, 1973 We have studied the evolution of ribosomal proteins over a spectrum of 13 species ranging from man to plants using a two‐dimensional polyacrylamide gel electrophoresis technique. We tried to quantify the proximity of these species by coelectrophoresing the proteins from various combinations of two species.
Francine Creusot +2 more
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