Results 211 to 220 of about 6,145,189 (363)

Surface‐Associated Proteins on Extracellular Vesicles Remodel the Tumor Microenvironment by Potentiating TGF‐β Signaling in a Contact‐Dependent Manner

Advanced Science, EarlyView.
Extracellular vesicles (EVs) released from TGF‐β‐activated CAFs are enriched with ECM proteins such as TSG6 and THBS1, which facilitate their binding to recipient cell membranes. This EV–cell interaction promotes the clustering of CD44 and TGF‐β receptors on the target cell surface, thereby potentiating TGF‐β signaling activity. This study highlights a
Chao Li, Agustin Enciso‐Martinez, Lizhe Zhu, Sarah A. Rotman, Peter A. van Veelen, Roman I. Koning, Hailiang Mei, Peter ten Dijke   +7 more
wiley   +1 more source

Extra-Ribosomal Roles for Ribosomal Proteins and Their Relevance to Tumour Suppression, Carcinogenesis and Cancer Progression. [PDF]

Cancers (Basel)
Pk S, Freimanis J, Kovala T, Parissenti AM.   +3 more
europepmc   +1 more source

HeLa ribosomal protein S6. Insulin and dibutyryl cyclic AMP affect different phosphopeptides.

, 1981
Stanley M. Lastick, Edwin H. McConkey
openalex   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Argonaute, Vault, and Ribosomal Proteins Targeted by Autoantibodies in Systemic Lupus Erythematosus. [PDF]

J Rheumatol, 2023
Moadab F, Wang X, Najjar R, Ukadike KC, Hu S, Hulett T, Bengtsson AA, Lood C, Mustelin T.   +8 more
europepmc   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

Functional Characterization and Heterogeneity Analysis of Ribosomal Proteins in Mouse Preimplantation Embryos. [PDF]

FASEB J
Lee SJ, Kim D, Han G, Hong SP, Choi I, Cho C.   +5 more
europepmc   +1 more source

RNA-binding motif protein 10 inactivates c-Myc by partnering with ribosomal proteins uL18 and uL5. [PDF]

Proc Natl Acad Sci U S A, 2023
Lee H, Jung JH, Ko HM, Park H, Segall AM, Sheffmaker RL, Wang J, Frey WD, Pham N, Wang Y, Zhang Y, Jackson JG, Zeng SX, Lu H.   +13 more
europepmc   +1 more source

Functions of ribosomal proteins in assembly of eukaryotic ribosomes in vivo.

Annual Review of Biochemistry, 2015
J. de la Cruz, K. Karbstein, J. Woolford
semanticscholar   +1 more source

Clinicopathological significance of ribosomal protein S6 kinase A6 in lung squamous cell carcinoma: an immunohistochemical and RNA-seq study.

, 2018
Ye‐Ying Fang, Fuchao Ma, Xuli Gan, Wenqi Luo, Rong‐Quan He, Huimin Xie, Shiyu Li, Gang Chen, Dan‐Ming Wei, Xiaohua Hu   +9 more
openalex   +1 more source