Results 21 to 30 of about 6,145,189 (363)

Roles of ribosomal proteins in hematologic disorders and cancers: a review

open access: yesEmergency and Critical Care Medicine, 2023
. Ribosomes are important organelles for synthesizing proteins in cells. They are composed of ribosomal RNA and more than 80 ribosomal proteins. It is well known that an essential function of ribosomal proteins is to participate in protein translation ...
Jie Wang, Feng Yan
doaj   +1 more source

Neuronal ribosomes exhibit dynamic and context-dependent exchange of ribosomal proteins

open access: yesNature Communications, 2021
Owing to their morphological complexity and dense network connections, neurons modify their proteomes locally, using mRNAs and ribosomes present in the neuropil (tissue enriched for dendrites and axons).
Claudia M. Fusco   +9 more
semanticscholar   +1 more source

Ribosomal proteins: mutant phenotypes by the numbers and associated gene expression changes [PDF]

open access: yesOpen Biology, 2020
Ribosomal proteins are highly conserved, many universally so among organisms. All ribosomal proteins are structural parts of the same molecular machine, the ribosome.
Michael Polymenis
doaj   +1 more source

Deregulation of ribosomal proteins in human cancers

open access: yesBioscience Reports, 2021
The ribosome, the site for protein synthesis, is composed of ribosomal RNAs (rRNAs) and ribosomal proteins (RPs). The latter have been shown to have many ribosomal and extraribosomal functions.
Wendy El Khoury, Z. Nasr
semanticscholar   +1 more source

The roles of ribosomal proteins in nasopharyngeal cancer: culprits, sentinels or both

open access: yesBiomarker Research, 2021
Ribosomal protein genes encode products that are essential for cellular protein biosynthesis and are major components of ribosomes. Canonically, they are involved in the complex system of ribosome biogenesis pivotal to the catalysis of protein ...
Edmund Ui-Hang Sim   +2 more
doaj   +1 more source

The Modular Adaptive Ribosome. [PDF]

open access: yesPLoS ONE, 2016
The ribosome is an ancient machine, performing the same function across organisms. Although functionally unitary, recent experiments suggest specialized roles for some ribosomal proteins.
Anupama Yadav   +5 more
doaj   +1 more source

Tagging of RPS9 as a tool for ribosome purification and identification of ribosome-associated proteins [PDF]

open access: yesArchives of Biological Sciences, 2021
Ribosomes, the catalytic machinery required for protein synthesis, are comprised of 4 ribosomal RNAs and about 80 ribosomal proteins in mammals. Ribosomes further interact with numerous associated factors that regulate their biogenesis and function.
Jovanović Bogdan   +3 more
doaj   +1 more source

Abnormal Expression of Mitochondrial Ribosomal Proteins and Their Encoding Genes with Cell Apoptosis and Diseases

open access: yesInternational Journal of Molecular Sciences, 2020
Mammalian mitochondrial ribosomes translate 13 proteins encoded by mitochondrial genes, all of which play roles in the mitochondrial respiratory chain.
Guomin Huang, Hongyan Li, Hong Zhang
semanticscholar   +1 more source

Involvement of Target of Rapamycin (TOR) Signaling in the Regulation of Crosstalk between Ribosomal Protein Small Subunit 6 Kinase-1 (RPS6K-1) and Ribosomal Proteins

open access: yesPlants, 2023
The target of rapamycin (TOR) protein phosphorylates its downstream effector p70kDa ribosomal protein S6 kinases (S6K1) for ribosome biogenesis and translation initiation in eukaryotes.
Achala Bakshi   +6 more
doaj   +1 more source

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins

open access: yesCell Reports, 2023
Summary: In mammals, about 99% of mitochondrial proteins are synthesized in the cytosol as precursors that are subsequently imported into the organelle. The mitochondrial health and functions rely on an accurate quality control of these imported proteins.
Julie Lavie   +11 more
doaj   +1 more source

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