Results 21 to 30 of about 6,124,063 (361)
Ribosomal proteins and human diseases: molecular mechanisms and targeted therapy
Signal Transduction and Targeted Therapy, 2021 Ribosome biogenesis and protein synthesis are fundamental rate-limiting steps for cell growth and proliferation. The ribosomal proteins (RPs), comprising the structural parts of the ribosome, are essential for ribosome assembly and function.
Jian Kang +5 more
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Roles of ribosomal proteins in hematologic disorders and cancers: a review
Emergency and Critical Care Medicine, 2023 . Ribosomes are important organelles for synthesizing proteins in cells. They are composed of ribosomal RNA and more than 80 ribosomal proteins. It is well known that an essential function of ribosomal proteins is to participate in protein translation ...
Jie Wang, Feng Yan
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Neuronal ribosomes exhibit dynamic and context-dependent exchange of ribosomal proteins
Nature Communications, 2021 Owing to their morphological complexity and dense network connections, neurons modify their proteomes locally, using mRNAs and ribosomes present in the neuropil (tissue enriched for dendrites and axons).
Claudia M. Fusco +9 more
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Ribosomal proteins: mutant phenotypes by the numbers and associated gene expression changes [PDF]
Open Biology, 2020 Ribosomal proteins are highly conserved, many universally so among organisms. All ribosomal proteins are structural parts of the same molecular machine, the ribosome.
Michael Polymenis
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Deregulation of ribosomal proteins in human cancers
Bioscience Reports, 2021 The ribosome, the site for protein synthesis, is composed of ribosomal RNAs (rRNAs) and ribosomal proteins (RPs). The latter have been shown to have many ribosomal and extraribosomal functions.
Wendy El Khoury, Z. Nasr
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The roles of ribosomal proteins in nasopharyngeal cancer: culprits, sentinels or both
Biomarker Research, 2021 Ribosomal protein genes encode products that are essential for cellular protein biosynthesis and are major components of ribosomes. Canonically, they are involved in the complex system of ribosome biogenesis pivotal to the catalysis of protein ...
Edmund Ui-Hang Sim +2 more
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The Modular Adaptive Ribosome. [PDF]
PLoS ONE, 2016 The ribosome is an ancient machine, performing the same function across organisms. Although functionally unitary, recent experiments suggest specialized roles for some ribosomal proteins.
Anupama Yadav +5 more
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Tagging of RPS9 as a tool for ribosome purification and identification of ribosome-associated proteins [PDF]
Archives of Biological Sciences, 2021 Ribosomes, the catalytic machinery required for protein synthesis, are comprised of 4 ribosomal RNAs and about 80 ribosomal proteins in mammals. Ribosomes further interact with numerous associated factors that regulate their biogenesis and function.
Jovanović Bogdan +3 more
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International Journal of Molecular Sciences, 2020 Mammalian mitochondrial ribosomes translate 13 proteins encoded by mitochondrial genes, all of which play roles in the mitochondrial respiratory chain.
Guomin Huang, Hongyan Li, Hong Zhang
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Evolution of Ribosomal Proteins [PDF]
European Journal of Biochemistry, 1973 We have studied the evolution of ribosomal proteins over a spectrum of 13 species ranging from man to plants using a two‐dimensional polyacrylamide gel electrophoresis technique. We tried to quantify the proximity of these species by coelectrophoresing the proteins from various combinations of two species.
J, Delaunay, F, Creusot, G, Schapira
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