Regulation of the cardiomyocyte transcriptome vs translatome by endothelin-1 and insulin: translational regulation of 5' terminal oligopyrimidine tract (TOP) mRNAs by insulin [PDF]
, 2010 Background: Changes in cellular phenotype result from underlying changes in mRNA transcription and translation. Endothelin-1 stimulates cardiomyocyte hypertrophy with associated changes in mRNA/protein expression and an increase in the rate of protein ...
Clerk, Angela +5 more
core +3 more sources
Concerted evolution in the ribosomal RNA cistron.
PLoS ONE, 2013 BackgroundGene conversion is the mechanism proposed to be responsible for the homogenization of multigene families such as the nuclear ribosomal gene clusters.
Kershney Naidoo +4 more
doaj +1 more source
Reconstructing phylogeny from RNA secondary structure via simulated evolution
, 2002 DNA sequences of genes encoding functional RNA molecules (e.g., ribosomal RNAs) are commonly used in phylogenetics (i.e. to infer evolutionary history).
Fischer, Will, Geard, Nicholas
core
Rlp7p is associated with 60S preribosomes, restricted to the granular component of the nucleolus, and required for pre-rRNA processing [PDF]
, 2002 Many analyses have examined subnucleolar structures in eukaryotic cells, but the relationship between morphological structures, pre-rRNA processing, and ribosomal particle assembly has remained unclear.
Gadal, O +6 more
core +2 more sources
Ribosomal RNA gene repeats, their stability and cellular senescence
Proceedings of the Japan Academy. Series B, Physical and biological sciences, 2014 The ribosomal RNA gene (rDNA) repeats form a historically well-researched region in the chromosome. Their highly repetitive structure can be identified easily which has enabled studies on DNA replication, recombination, and transcription.
Takehiko Kobayashi
semanticscholar +1 more source
Effect of restricted mobility on RNA content and nucleotide composition and on protein content in motoneurons of spinal cord anterior horns [PDF]
An investigation into the effect of hypokinesia on the ribonucleic acid (RNA) content, the nucleotide composition, and dynamics of protein content in the motoneuron of the rat spinal cord anterior horns is described.
Gorbunova, A. V.
core +1 more source
How to fold and protect mitochondrial ribosomal RNA with fewer guanines [PDF]
, 2018 Mammalian mitochondrial ribosomes evolved from bacterial ribosomes by reduction of ribosomal RNAs, increase of ribosomal protein content, and loss of guanine nucleotides. Guanine is the base most sensitive to oxidative damage. By systematically comparing
Hosseini, Maryam +5 more
core +1 more source
Size, shape, and flexibility of RNA structures
, 2006 Determination of sizes and flexibilities of RNA molecules is important in understanding the nature of packing in folded structures and in elucidating interactions between RNA and DNA or proteins.
Cantor C. R. +4 more
core +1 more source
SARS-CoV-2 targets ribosomal RNA biogenesis
Cell ReportsSummary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hinders host gene expression, curbing defenses and licensing viral protein synthesis and virulence.
V. Talya Yerlici +9 more
doaj
The complete mitochondrial genome of Glossaulax reiniana (Littorinimorpha: Naticidae)
Mitochondrial DNA. Part B. Resources, 2018 In the present study, the complete mitochondrial genome of Glossaulax reiniana was determined using the next-generation sequencing. The circular genome was found to be 15,254 bp in length and had an overall nucleotide composition of 30.6% A, 14.1% C, 15 ...
Peng-Yu Li +3 more
doaj +1 more source