Results 91 to 100 of about 1,110,020 (298)

The Protist Ribosomal Reference database (PR2): a catalog of unicellular eukaryote Small Sub-Unit rRNA sequences with curated taxonomy [PDF]

, 2012
The interrogation of genetic markers in environmental meta-barcoding studies is currently seriously hindered by the lack of taxonomically curated reference data sets for the targeted genes.
Probert, Ian, Dolan, John R., Kooistra, Wiebe H.C.F., Guillou, Laure, Vaulot, Daniel, Campo, Javier, Del, Morard, Raphael, Bass, David, Logares, Ramiro, Montresor, Marina, del Campo, Javier, Lara, Enrique, Berney, Cédric, Zimmermann, Pascal, Burgaud, Gaétan, Pawlowski, Jan, Campo, Javier,, Bachar, Dipankar, Boutte, Christophe, Bittner, Lucie, Christen, Richard, Mahe, Frédéric, Dunthorn, Micah, Kooistra, Wiebe H. C. F., ,, Siano, Raffaele, Stoeck, Thorsten, Le Bescot, Noan, Audic, Stéphane, Decelle, Johan, Not, Fabrice, Massana, Ramon, de Vargas, Colomban, Sauvadet, Anne-Laure, Edvardsen, Bente, Holzmann, Maria   +35 more
core   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

NoRC, a novel chromatin remodeling complex involved in ribosomal RNA gene silencing [PDF]

, 2004
Regulation of gene expression takes place in the nucleus in a highly structured and condensed nucleoprotein environment, called chromatin (Felsenfeld and Groudine, 2003; Khorasanizadeh, 2004; Vaquero et al., 2003).
Strohner, Ralf
core   +1 more source

The Beak of Eukaryotic Ribosomes: Life, Work and Miracles

Biomolecules
Ribosomes are not totally globular machines. Instead, they comprise prominent structural protrusions and a myriad of tentacle-like projections, which are frequently made up of ribosomal RNA expansion segments and N- or C-terminal extensions of ribosomal ...
Sara Martín-Villanueva, Carla V. Galmozzi, Carmen Ruger-Herreros, Dieter Kressler, Jesús de la Cruz   +4 more
doaj   +1 more source

RNA–Protein Interactions Prevent Long RNA Duplex Formation: Implications for the Design of RNA-Based Therapeutics

Molecules, 2018
Cells frequently simultaneously express RNAs and cognate antisense transcripts without necessarily leading to the formation of RNA duplexes. Here, we present a novel transcriptome-wide experimental approach to ascertain the presence of accessible double ...
Eckart Bindewald, Lisheng Dai, Wojciech K. Kasprzak, Taejin Kim, Shuo Gu, Bruce A. Shapiro   +5 more
doaj   +1 more source

Methylation of Ribosomal RNA: A Mitochondrial Perspective

Frontiers in Genetics, 2020
Ribosomal RNA (rRNA) from all organisms undergoes post-transcriptional modifications that increase the diversity of its composition and activity. In mitochondria, specialized mitochondrial ribosomes (mitoribosomes) are responsible for the synthesis of 13
M. Isabel G. Lopez Sanchez, M. Isabel G. Lopez Sanchez, Miriam Cipullo, Miriam Cipullo, Shreekara Gopalakrishna, Shreekara Gopalakrishna, Anas Khawaja, Anas Khawaja, Joanna Rorbach, Joanna Rorbach   +9 more
doaj   +1 more source

Rlp7p is associated with 60S preribosomes, restricted to the granular component of the nucleolus, and required for pre-rRNA processing [PDF]

, 2002
Many analyses have examined subnucleolar structures in eukaryotic cells, but the relationship between morphological structures, pre-rRNA processing, and ribosomal particle assembly has remained unclear.
Tollervey, D, Hurt, E, Pierre-Emmanuel Gleizes, Elisabeth Petfalski, Ed Hurt, Olivier Gadal, David Tollervey, Gleizes, P E, Strauss, D, Gas, N, Daniela Strauss, Gadal, O, Petfalski, E, Nicole Gas   +13 more
core   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

Ribosomal RNA Processing and Ribosome Biogenesis in Eukaryotes [PDF]

IUBMB Life, 2004
AbstractIn eukaryotes nearly 500 rRNAs, ribosomal proteins, snoRNAs and trans‐acting factors contribute to ribosome biogenesis. After more than 30 years of intense research, the incredible complexities of nucleolar function are revealed but details often remain unclear. Here we review this progress and the many intriguing questions which remain.
openaire   +2 more sources

Molecular phylogeny of brachiopods and phoronids based on nuclear-encoded small subunit ribosomal RNA gene sequences [PDF]

, 1998
Brachiopod and phoronid phylogeny is inferred from SSU rDNA sequences of 28 articulate and nine inarticulate brachiopods, three phoronids, two ectoprocts and various outgroups, using gene trees reconstructed by weighted parsimony, distance and maximum ...
A. Gawthrop, T. Cavalier–Smith, B. L. Cohen, Gawthrop, A., Cavalier-Smith, T., Cohen, B.L.   +5 more
core   +1 more source