Results 51 to 60 of about 509,011 (342)

Ribosomal RNA regulates chromosome clustering during mitosis

Cell Discovery, 2022
Noncoding RNAs are known to associate with mitotic chromosomes, but the identities and functions of chromosome-associated RNAs in mitosis remain elusive. Here, we show that rRNA species associate with condensed chromosomes during mitosis.
Kai Ma, Man Luo, Guanglei Xie, Xi Wang, Qilin Li, Lei Gao, Hongtao Yu, Xiaochun Yu   +7 more
doaj   +1 more source

RNA processing: Pocket guides to ribosomal RNA [PDF]

Current Biology, 1997
The functional role of a recently identified class of small nucleolar (sno) RNAs has been elucidated: the 'box H/ACA' snoRNAs act as guide RNAs, specifying the position of evolutionarily conserved pseudouridines in ribosomal (r)RNA via an rRNA-snoRNA base-pairing interaction that forms a 'pseudouridine pocket'.
openaire   +3 more sources

Idiosyncratic evolution of conserved eukaryote proteins that are similar in sequence to archaeal or bacterial proteins [PDF]

, 2008
Sequence comparisons have been made between the proteins of 571 prokaryote species including 46 archaea and 525 bacteria and the set of human proteins.
Roy J. Britten
core   +2 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Distinct RNA profiles in subpopulations of extracellular vesicles: apoptotic bodies, microvesicles and exosomes [PDF]

, 2013
Introduction: In recent years, there has been an exponential increase in the number of studies aiming to understand the biology of exosomes, as well as other extracellular vesicles.
Berent-Maoz B, Chaput N, Choi DS, Cocucci E, Droin N, Ekström K, Escola JM, Freyssinet JM, György B, Johnstone RM, Kalra H, Keller S, Lehmann BD, Lespagnol A, Lässer C, Lässer C, Mathivanan S, Rajendran L, Ratajczak J, Simpson RJ, Stoorvogel W, Suliman A, Théry C, Turiák L, Valadi H, van der Pol E, van der Pol E, van Niel G, Yu X   +28 more
core   +2 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Description of Pseudobenedeniella johnstoni sp. n. (Monogenea: Capsalidae) from the gills of Antarctic black rockcod, Notothenia coriiceps Richardson in coastal waters of West Antarctica

Helminthologia
Morphological and metrical analyses of monogeneans from the gills of Antarctic rockcod Notothenia coriiceps revealed the presence of a new species, Pseudobenedeniella johnstoni sp. n. Fresh specimens of monogeneans collected from N.
Rubtsova N. Y., Chaudhary A., Glotov S., Kuzmina T. A.   +3 more
doaj   +1 more source

Selection of Peptides Targeting Helix 31 of Bacterial 16S Ribosomal RNA by Screening M13 Phage-Display Libraries

Molecules, 2011
Ribosomal RNA is the catalytic portion of ribosomes, and undergoes a variety of conformational changes during translation. Structural changes in ribosomal RNA can be facilitated by the presence of modified nucleotides. Helix 31 of bacterial 16S ribosomal
Christine S. Chow, Anne-Cécile E. Duc, Philip R. Cunningham, Tek N. Lamichhane, N. Dinuka Abeydeera   +4 more
doaj   +1 more source

Structural basis of ribosomal RNA transcription regulation

Nature Communications, 2021
Ribosomal RNA (rRNA) expression is regulated at the initiation stage of RNA synthesis. Here, the authors report cryo-EM structures of E. coli RNA polymerase and rRNA promoter complex with DksA/ppGpp on the way to open complex formation, identifying key ...
Yeonoh Shin, M. Zuhaib Qayyum, Danil Pupov, Daria Esyunina, Andrey Kulbachinskiy, Katsuhiko S. Murakami   +5 more
doaj   +1 more source

Control of Nucleotide Metabolism and Ribosomal Ribonucleic Acid Synthesis During Nitrogen Starvation of \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]

, 1972
Ribosomal ribonucleic acid (RNA) synthesis and ribonucleoside triphosphate metabolism were studied in cultures of Escherichia coli subjected to starvation for inorganic nitrogen.
Irr, Joseph D.
core   +1 more source