Results 151 to 160 of about 25,784 (242)

An unusual type I ribosome-inactivating protein from Agrostemma githago L. [PDF]

open access: yesSci Rep, 2020
Weise C   +7 more
europepmc   +1 more source

Distinct 5′ UTR Requirements for Translation of the Bicistronic X/P mRNA Among Avian Orthobornaviruses

open access: yesMicrobiology and Immunology, Volume 70, Issue 2, Page 80-90, February 2026.
ABSTRACT Orthobornaviruses express X and the phosphoprotein (P) from a bicistronic X/P mRNA, and these proteins regulate polymerase activity. In mammalian orthobornaviruses, the 5′ untranslated region (5′ UTR) of the X/P mRNA controls the translational balance between X and P and thereby promotes efficient replication.
Meng‐Chi Wu   +7 more
wiley   +1 more source

Plant AB toxins with lectin domains [PDF]

open access: yes, 2017
Dang, Liuyi   +2 more
core   +2 more sources

The Role of the Gut Microbiome in the Complex Network of Frailty Syndrome and Associated Comorbidities in Aging

open access: yesAging Cell, Volume 25, Issue 2, February 2026.
This study analyzed gut microbiota in older adults with and without Frailty Syndrome by 16S rRNA gene sequencing and metagenomics. Frailty was associated with altered microbial composition, metabolic functions, and increased antimicrobial resistance, whereas non‐frail individuals showed healthier profiles.
Ana Barberá   +5 more
wiley   +1 more source

Aktivitas Kitinase dan Peroksidase dari Ekstrak Kasar Protein Asal Kalus dan Berbagai Jaringan Tanaman Trichosanthes Cucumerina Var. Anguina [PDF]

open access: yes, 2012
Chitinase and peroxydase are important bioactive proteins or are specific enzymes that are related to plant resistance to pathogens. The aims of the research were to analyze the chitinase and peroxidase activities of crude protein extract from calli ...
Artika, I. M. (I)   +5 more
core  

The FsrA‐Mediated Iron‐Sparing Response Regulates the Biosynthesis of the Epipeptide EPE in Bacillus subtilis

open access: yesMolecular Microbiology, Volume 125, Issue 2, Page 108-122, February 2026.
Under iron‐limited conditions, FsrA base‐pairs with the intergenic region between epeX and epeE, enhancing epeE translation and triggering EPE production. Toxin‐mediated cell lysis releases nutrients, including iron, which can be taken up by surviving cells.
Sarah Miercke   +3 more
wiley   +1 more source

Design and in vivo characterization of self-inactivating human and non-human lentiviral expression vectors engineered for streptogramin-adjustable transgene expression [PDF]

open access: yes, 2017
Adjustable transgene expression is considered key for next-generation molecular interventions in gene therapy scenarios, therapeutic reprogramming of clinical cell phenotypes for tissue engineering and sophisticated gene-function analyses in the post ...
Fussenegger, Martin   +3 more
core  

Manipulation of the Unfolded Protein Response by Intracellular Bacterial Pathogens: Mechanisms of ER Hijacking and Therapeutic Implications

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
This review illustrates how intracellular bacterial pathogens—such as Brucella, Mycobacterium tuberculosis, and Legionella—secrete effector proteins that specifically target the IRE1α, PERK, and ATF6 branches of the unfolded protein response (UPR) to hijack ER stress signaling.
Enhui Dai   +5 more
wiley   +1 more source

Lysophosphatidic Acid Synergizes With 1,25‐Dihydroxyvitamin D to Promote Fibroblast Growth Factor‐23 Synthesis via MAPK Signaling and Induction of the IL12A Gene

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Ay et al. investigated the cellular mechanisms behind the role of lysophosphatidic acid (LPA) in FGF23 production. They revealed that LPA cooperates with 1,25‐dihydroxyvitamin D (1,25D), that is, the bioactive form of vitamin D known to stimulate FGF23 synthesis. This synergy entails MAPK signaling and the induction of the gene encoding the interleukin‐
Birol Ay   +7 more
wiley   +1 more source

Mayahuelin, a Type I Ribosome Inactivating Protein: Characterization, Evolution, and Utilization in Phylogenetic Analyses of Agave. [PDF]

open access: yesFront Plant Sci, 2020
Lledías F   +9 more
europepmc   +1 more source

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