Inhibition of HIV-1 replication by balsamin, a ribosome inactivating protein of Momordica balsamina. [PDF]
PLoS ONE, 2013 Ribosome-inactivating proteins (RIPs) are endowed with several medicinal properties, including antiviral activity. We demonstrate here that the recently identified type I RIP from Momordica balsamina also possesses antiviral activity, as determined by ...
Inderdeep Kaur +5 more
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Extensive Evolution of Cereal Ribosome-Inactivating Proteins Translates into Unique Structural Features, Activation Mechanisms, and Physiological Roles [PDF]
Toxins, 2017 Ribosome-inactivating proteins (RIPs) are a class of cytotoxic enzymes that can depurinate rRNAs thereby inhibiting protein translation. Although these proteins have also been detected in bacteria, fungi, and even some insects, they are especially ...
Jeroen De Zaeytijd, Els J. M. Van Damme
doaj +4 more sources
In-silico analysis of ribosome inactivating protein (RIP) of the Cucurbitaceae family
AMB ExpressRibosome-inactivating proteins (RIPs) are highly active N-glycosidases that depurinate both bacterial and eukaryotic rRNAs, halting protein synthesis during translation.
Quratulain Maqsood +5 more
doaj +3 more sources
Novel Ribosome-inactivating Protein (RIP) Isolated from Trichosanthes dioica Induces Apoptosis in HeLa Cell Line [PDF]
International Journal of Bio-Resource and Stress Management, 2021 Ribosome-inactivating proteins (RIPs) are toxic N-glycosidases that depurinate eukaryotic and prokaryotic rRNAs and thus interrupt protein synthesis during translation.
T. Ghosh +3 more
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Molecular Characterization of the Recombinant A-chain of a Type II Ribosome-Inactivating Protein (RIP) from Viscum album coloratum and Structural Basis on its Ribosome-Inactivating Activity and the Sugar-binding Properties of the B-chain [PDF]
BMB Reports, 2006 Mistletoe (Viscum album) lectins, which are classified as a type II ribosome-inactivating protein (RIP) due to their unique biological function and the potential medical and therapeutic application in cancer cells, receive a rising attention. The heterodimeric glycoproteins contain the Achain with catalytic activity and the B-chain with sugar binding ...
Ravi Prakash Reddy Nanga +2 more
exaly +4 more sources
Journal of King Saud University - Science, 2020 Abstract Ribosome Inactivating Proteins (RIPs), are plant proteins with N Glycosidase activity. Annona squamosa is traditionally used in medicine but RIP presence is less explored. The present study aimed to isolate and structurally analyse RIP- like protein from the seeds of Annona squamosa (ARIP) and investigate its in vitro pharmacological ...
J Jannet Vennila
exaly +2 more sources
CYTOTOXICITY AGAINST TUMOR CELL LINES OF A RIBOSOME-INACTIVATING PROTEIN (RIP)-LIKE PROTEIN ISOLATED FROM LEAVES OF MIRABILIS JALAPA L. [PDF]
Malaysian Journal of Pharmaceutical Sciences, 2006 The 30 kD protein fraction with properties like ribosome-inactivating protein (RIP) was isolated from the leaves of Mirabilis jalapa L. and named MJ-30. This study investigated the cytotoxic effect of MJ-30 on normal and malignant cells.
ZULLIES IKAWATI, SUDJADI, SISMINDARI
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Maize ribosome-inactivating protein uses Lys158-lys161 to interact with ribosomal protein P2 and the strength of interaction is correlated to the biological activities. [PDF]
PLoS ONE, 2012 Ribosome-inactivating proteins (RIPs) inactivate prokaryotic or eukaryotic ribosomes by removing a single adenine in the large ribosomal RNA. Here we show maize RIP (MOD), an atypical RIP with an internal inactivation loop, interacts with the ribosomal ...
Yuen-Ting Wong +5 more
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RIBOSOME-INACTIVATED PROTEINS (RIPS) OF THE BLACK ELDER SAMBUCUS NIGRA
chemistry of plant raw material, 2023 The aim of this work is to study the composition of ribosome-inactivating proteins from the bark and berries of the black elderberry Sambucus nigra L., growing on the territory of the Republic of Uzbekistan. The composition of ribosome-inactivating proteins in the bark and berries of black elder Sambucus nigra L., collected in the Botanical ...
Khilola Tozhimurodovna Agzamkhuzhaeva +2 more
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The Potential of RIP (Ribosome Inactivating Protein) as Biopesticides [PDF]
Buletin Eboni, 2019 RIP (Ribosome Inactivating Protein) produced by plants that can act as a plant defense from pest and disease. This protein is widely used as an anti-fungal, anti-bacterial, anti-virus and anti-insect. Therefore, RIP contained in plants has the potential to be used for environmentally friendly biopesticides.
Tati Suharti, Dharmawati F Djam’an
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