Results 111 to 120 of about 24,039 (208)

Review of the ethnobotany, phytochemistry, pharmacology, and toxicity studies of the genus Adenia

Frontiers in Pharmacology
BackgroundThe genus Adenia has a rich history of traditional medicinal use across various cultures, particularly in Africa and parts of Asia. The present review summarizes key features of the genus Adenia, focusing on its occurrence, distribution ...
Iliassou L. Mouafon, David R. Katerere
doaj   +1 more source

Integrated Transcriptome and Proteome Analysis Provides Insight into the Ribosome Inactivating Proteins in Plukenetia volubilis Seeds. [PDF]

Int J Mol Sci, 2022
Liu G, Wu Z, Peng Y, Shang X, Gao L.
europepmc   +1 more source

Ricinus Agglutinin Induced Autophagy in Glioblastoma Cells [PDF]

, 2015
Ricinus agglutinin (RA) is a heterodimer consisting of two chains known as chain A and chain B respectively. The molecular weight of RA is 120 kD. RA is highly toxic to normal cells due to its ability to bind to the carbohydrate moieties present on the ...
Sahoo, puja
core  

Protecting the proteome: Eukaryotic cotranslational quality control pathways. [PDF]

, 2014
The correct decoding of messenger RNAs (mRNAs) into proteins is an essential cellular task. The translational process is monitored by several quality control (QC) mechanisms that recognize defective translation complexes in which ribosomes are stalled on
Bennett, Eric J, Lykke-Andersen, Jens
core   +2 more sources

Dynamics of the CD9 interactome during bacterial infection of epithelial cells by proximity labelling proteomics

The FEBS Journal, EarlyView.
We describe the CD9 interactome in epithelial cells for the first time. The interactome is diverse and dynamic and changes dependent on infection with specific bacteria. We validate these data by showing functional interaction between CD9 with CD44 or CD147. We therefore demonstrate that CD9 is a universal organiser of bacterial adhesion platforms able
Paige A. Wolverson, Isabel Fernandes Parreira, Ruth H. Thompson, Mark O. Collins, Jonathan G. Shaw, Luke R. Green   +5 more
wiley   +1 more source

Inhibition of post-transcriptional steps in ribosome biogenesis confers cytoprotection against chemotherapeutic agents in a p53-dependent manner

Scientific Reports, 2017
The p53-mediated nucleolar stress response associated with inhibition of ribosomal RNA transcription was previously shown to potentiate killing of tumor cells. Here, we asked whether targeting of ribosome biogenesis can be used as the basis for selective
Russell T. Sapio, Anastasiya N. Nezdyur, Matthew Krevetski, Leonid Anikin, Vincent J. Manna, Natalie Minkovsky, Dimitri G. Pestov   +6 more
doaj   +1 more source

Isomorphic Fluorescent Nucleosides Facilitate Real-Time Monitoring of RNA Depurination by Ribosome Inactivating Proteins. [PDF]

Chemistry, 2022
Cong D, Li Y, Ludford PT, Tor Y.
europepmc   +1 more source

Expression of the alpha-thionin gene from barley in tobacco confers enhanced resistance to bacterial pathogens [PDF]

, 1993
Thionins are cysteine-rich, 5 kDa polypeptides which are toxic to plant pathogens in vitro. Expression of the gene encoding alpha-thionin from barley endosperm, under the 35S promoter from cauliflower mosaic virus, conferred to transgenic tobacco ...
Carmona Quiles, Maria Jose, Fernandez, Jose A., García Olmedo, Francisco, Lopez Fando, J.J., Molina Fernández, Antonio   +4 more
core   +2 more sources

ER proteostasis meets mitochondrial function: contact sites as hubs of communication and therapeutic targets

The FEBS Journal, EarlyView.
Proteostasis ensures proper protein folding, modification, and degradation, while its impairment triggers ER stress. Chronic ER stress and maladaptive UPR via the CHOP–ERO1 axis remodel ERMCs, altering calcium signaling and mitochondrial metabolism.
Giorgia Maria Renna, Alessandro Cherubini, Ersilia Varone, Serena Germani, Alice Marrazza, Ester Zito   +5 more
wiley   +1 more source

Structure and Biological Properties of Ribosome-Inactivating Proteins and Lectins from Elder (Sambucus nigra L.) Leaves. [PDF]

Toxins (Basel), 2022
Iglesias R, Russo R, Landi N, Valletta M, Chambery A, Di Maro A, Bolognesi A, Ferreras JM, Citores L.   +8 more
europepmc   +1 more source