Antifungal Activity of Ribosome-Inactivating Proteins [PDF]
ToxinsThe control of crop diseases caused by fungi remains a major problem and there is a need to find effective fungicides that are environmentally friendly.
Rosario Iglesias +3 more
doaj +6 more sources
Ribosome-Inactivating and Related Proteins [PDF]
Toxins, 2015 Ribosome-inactivating proteins (RIPs) are toxins that act as N-glycosidases (EC 3.2.2.22). They are mainly produced by plants and classified as type 1 RIPs and type 2 RIPs.
Joachim Schrot +2 more
doaj +7 more sources
Special Issue: Ribosome-Inactivating Proteins—Commemorative Issue in Honor of Professor Fiorenzo Stirpe [PDF]
Molecules, 2017 The family of ribosome-inactivating proteins (RIPs) groups all enzymes (EC.3.2.2.22) with a so-called RIP domain which comprises N-glycosidase activity and enables these proteins to catalytically inactivate ribosomes.[...]
Els J.M. Van Damme
doaj +4 more sources
Elderberries: A Source of Ribosome-Inactivating Proteins with Lectin Activity [PDF]
Molecules, 2015 Sambucus (Adoxaceae) species have been used for both food and medicine purposes. Among these, Sambucus nigra L. (black elder), Sambucus ebulus L. (dwarf elder), and Sambucus sieboldiana L. are the most relevant species studied.
Jesús Tejero +7 more
doaj +6 more sources
The ribosome-inactivating proteins MAP30 and Momordin inhibit SARS-CoV-2 [PDF]
PLoS ONE, 2023 The continuing emergence of SARS-CoV-2 variants has highlighted the need to identify additional points for viral inhibition. Ribosome inactivating proteins (RIPs), such as MAP30 and Momordin which are derived from bitter melon (Momordica charantia), have
Norman R. Watts +7 more
doaj +3 more sources
Engineering of Ribosome-inactivating Proteins for Improving Pharmacological Properties [PDF]
Toxins, 2020 Ribosome-inactivating proteins (RIPs) are N-glycosidases, which depurinate a specific adenine residue in the conserved α-sarcin/ricin loop (α-SRL) of rRNA.
Jia-Qi Lu +3 more
doaj +2 more sources
Ribosome-inactivating proteins: potent poisons and molecular tools. [PDF]
Virulence, 2013 Ribosome-inactivating proteins (RIPs) were first isolated over a century ago and have been shown to be catalytic toxins that irreversibly inactivate protein synthesis.
Walsh MJ, Dodd JE, Hautbergue GM.
europepmc +5 more sources
Plants Producing Ribosome-Inactivating Proteins in Traditional Medicine [PDF]
Molecules, 2016 Ribosome-inactivating proteins (RIPs) are enzymes that deadenylate nucleic acids and are broadly distributed in the plant kingdom. Many plants that contain RIPs are listed in the pharmacopoeias of folk medicine all over the world, mostly because of their
Letizia Polito +4 more
doaj +2 more sources
Ribosome-Inactivating Proteins of Bougainvillea glabra Uncovered Polymorphism and Active Site Divergence [PDF]
Toxins, 2021 Ribosome-inactivating proteins (RIPs) are toxic proteins that can inhibit protein synthesis. RIPs purified from Bougainvillea have low nonspecific toxicity, showing promise for processing applications in the agricultural and medical fields.
Yihua Lin +6 more
doaj +2 more sources
Functional Assays for Measuring the Catalytic Activity of Ribosome Inactivating Proteins [PDF]
Toxins, 2018 Ribosome-inactivating proteins (RIPs) are potent toxins that inactivate ribosomes by catalytically removing a specific adenine from the α-sarcin/ricin loop (SRL) of the large rRNA.
Yijun Zhou +3 more
doaj +2 more sources