Results 31 to 40 of about 1,593,797 (211)

Molecularly imprinted polymers for protome analysis [PDF]

open access: yes, 2008
Fast and efficient methods for the detection of insurgence and progression of diseases are at the basis of modern diagnostics and medicine. In this concern, biomarkers represent a powerful diagnostic tool, as their expression profiles well correlate ...
Bonini, Francesca
core   +7 more sources

Ribosome Inactivating Proteins and Apoptosis

open access: yes, 2010
Ribosome inactivating proteins (RIPs) are RNA N-glycosidases which potently inhibit translation by inactivating ribosomes. RIPs have also been shown to possess the ability to induce apoptosis.
Batra, Janendra K.   +3 more
core   +2 more sources

Plant-Derived Type I Ribosome Inactivating Protein-Based Targeted Toxins: A Review of the Clinical Experience

open access: yesToxins, 2022
Targeted toxins (TT) for cancer treatment are a class of hybrid biologic comprised of a targeting domain coupled chemically or genetically to a proteinaceous toxin payload.
David J. Flavell, Sopsamorn U. Flavell
doaj   +1 more source

Maize ribosome-inactivating protein uses Lys158-lys161 to interact with ribosomal protein P2 and the strength of interaction is correlated to the biological activities. [PDF]

open access: yesPLoS ONE, 2012
Ribosome-inactivating proteins (RIPs) inactivate prokaryotic or eukaryotic ribosomes by removing a single adenine in the large ribosomal RNA. Here we show maize RIP (MOD), an atypical RIP with an internal inactivation loop, interacts with the ribosomal ...
Yuen-Ting Wong   +5 more
doaj   +1 more source

RIPpore: A Novel Host-Derived Method for the Identification of Ricin Intoxication through Oxford Nanopore Direct RNA Sequencing

open access: yesToxins, 2022
Ricin is a toxin which enters cells and depurinates an adenine base in the sarcin-ricin loop in the large ribosomal subunit, leading to the inhibition of protein translation and cell death.
Yan Ryan   +6 more
doaj   +1 more source

Anti-Human Endoglin (hCD105) Immunotoxin—Containing Recombinant Single Chain Ribosome-Inactivating Protein Musarmin 1

open access: yesToxins, 2016
Endoglin (CD105) is an accessory component of the TGF-β receptor complex, which is expressed in a number of tissues and over-expressed in the endothelial cells of tumor neovasculature.
Begoña Barriuso   +7 more
doaj   +1 more source

Plant Toxins as Potential Alternatives to Botulinum Toxin for Eye-Movement Disorder Therapy

open access: yesStresses, 2023
The most successful alternative to traditional surgery for ocular muscle spasm treatment is the intramuscular injection of botulinum toxin (BTX), which allows the maintenance of the muscle dynamics and the absence of scars.
Massimo Bortolotti   +5 more
doaj   +1 more source

Combination of Balsamin and Flavonoids Induce Apoptotic Effects in Liver and Breast Cancer Cells

open access: yesFrontiers in Pharmacology, 2020
Flavonoids such as naringenin, quercetin, and naringin are known to exhibit anticancer properties. In this study, we examined the effects of these flavonoids on cell viability and apoptotic pathways of cancer cells, either singly or in combination with ...
Parminder K. Ajji   +3 more
doaj   +1 more source

Effect of transgenic tobacco plant, Nicotiana tabacum expressing ribosome inactivating gene isolated from the bulbs of Dutch iris, Iris hollandica on biological parameters of Myzus nicotianae (Hem.: Aphididea) and Spodoptera exigua (Lep.: Noctuidae) [PDF]

open access: yesنامه انجمن حشره‌شناسی ایران, 2015
The use of modified crop plants through gene transfer between different plant species plays an important role in pest control programs. We have investigated the insecticidal properties of two lines of tobacco transgenic plant consisting of IRIP ...
Sh. Shahidi-Noghabi
doaj  

Ribosome-inactivating Proteins from Phytolaccaceae

open access: yes, 2014
The plant family Phytolaccaceae is a rich source of ribosome-inactivating proteins (RIPs), including the first characterized non-toxic type 1 RIP, pokeweed antiviral protein from the plant Phytolacca americana. The antiviral property is important because
DI MARO, Antimo   +9 more
core   +1 more source

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