The proteasome cap RPT5/Rpt5p subunit prevents aggregation of unfolded ricin A chain [PDF]
, 2013 The plant cytotoxin ricin enters mammalian cells by receptor-mediated endocytosis, undergoing retrograde transport to the endoplasmic reticulum (ER) where its catalytic A chain (RTA) is reductively separated from the holotoxin to enter the cytosol and ...
Afshar +61 more
core +2 more sources
Enhanced strategies for cuproptosis‐like death in bacterial infection treatment
BMEMat, EarlyView.This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang +7 more
wiley +1 more source
Aktivitas Kitinase dan Peroksidase dari Ekstrak Kasar Protein Asal Kalus dan Berbagai Jaringan Tanaman Trichosanthes Cucumerina Var. Anguina [PDF]
, 2012 Chitinase and peroxydase are important bioactive proteins or are specific enzymes that are related to plant resistance to pathogens. The aims of the research were to analyze the chitinase and peroxidase activities of crude protein extract from calli ...
Artika, I. M. (I) +5 more
core
Bioactive proteins and peptides isolated from Chinese medicines with pharmaceutical potential. [PDF]
, 2014 Some protein pharmaceuticals from Chinese medicine have been developed to treat cardiovascular diseases, genetic diseases, and cancer. Bioactive proteins with various pharmacological properties have been successfully isolated from animals such as Hirudo ...
CHEUNG, HP +13 more
core +3 more sources
The power of many: when genetics met yeasts and high‐throughput
Biological Reviews, EarlyView.ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley +1 more source
Lectin Digestibility and Stability of Elderberry Antioxidants to Heat Treatment In Vitro
Molecules, 2017 Elderberry contains healthy low molecular weight nutraceuticals and lectins which are sequence-related to the elderberry allergen Sam n1. Some of these lectins are type II ribosome-inactivating proteins.
Pilar Jiménez +5 more
doaj +1 more source
Metodologia de extração de proteínas em torta de mamona e pinhão manso para análise por eletroforese (SDS-PAGE). [PDF]
, 2013 bitstream/item/74838/1/pub-151 ...
ASCHERI, J. L. R. +3 more
core
Immunotoxins and Anticancer Drug Conjugate Assemblies: The Role of the Linkage between Components [PDF]
, 2011 Immunotoxins and antibody-drug conjugates are protein-based drugs combining a target-specific binding domain with a cytotoxic domain. Such compounds are potentially therapeutic against diseases including cancer, and several clinical trials have shown ...
Franco Dosio, Luigi Cattel, Paola Brusa
core +3 more sources
Developmental Dynamics, EarlyView.Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff +6 more
wiley +1 more source
Ebulin from Dwarf Elder (Sambucus ebulus L.): A Mini-Review
Toxins, 2015 Sambucus ebulus L. (dwarf elder) is a medicinal plant, the usefulness of which also as food is restricted due to its toxicity. In the last few years, both the chemistry and pharmacology of Sambucus ebulus L. have been investigated.
Pilar Jiménez +6 more
doaj +1 more source