Results 111 to 120 of about 3,389,294 (250)

A Ribosome–Inactivating Protein fromAmaranthus viridis

open access: yesBioscience, Biotechnology, and Biochemistry, 1997
An antiviral protein purified from the leaves of Amaranthus viridis was named amaranthin. The in vivo antiviral activity of amaranthin was confirmed in tobacco mosaic virus (TMV) infection test on Nicotiana glutinosa leaves. The molecular mass of the amaranthin was estimated about 30 kDa by SDS-PAGE and the pI was measured as 9.8 by isoelectric ...
KWON, Seok-Yoon   +3 more
openaire   +2 more sources

Identification of Yeast Protein Sequences With Similarity to the ESCRT‐III Protein Snf7

open access: yesYeast, EarlyView.
ABSTRACT Endosomal sorting complex required for transport (ESCRT‐III) is a membrane remodeling complex involved in a large number of cellular processes. It appears to perform an essential function in eukaryotes, since to date no eukaryotic organism completely devoid of ESCRT‐III has been found.
Thomas Brune, Ralf Kölling
wiley   +1 more source

Yeast Knockout Strain Collection: Driving Functional Genomics, Biotechnological Applications and Human Disease Research

open access: yesYeast, EarlyView.
ABSTRACT The knockout strain collection of Saccharomyces cerevisiae has served as a valuable resource for functional genomics and yeast‐based biotechnology studies. A comprehensive single‐gene knockout strain collection, covering nearly all non‐essential genes, together with complementary mutant collections for essential genes, including temperature ...
Takashi Hirasawa
wiley   +1 more source

Red lines and green lights: Gene therapy for inherited erythroid disorders beyond the haemoglobinopathies

open access: yesBritish Journal of Haematology, EarlyView.
Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi   +3 more
wiley   +1 more source

Comparative analysis of the interaction sites of curcin, curcin C with adenine

open access: yes四川大学学报. 自然科学版, 2020
The ribosome-inactivating proteins of Jatropha curcas curcin and curcin C have antitumor activity, but the activity level of the latter is significantly higher than the former.
WU Peng   +3 more
doaj  

Olfactory proteomics reveals the capacity of the HDAC1 inhibitor pyroxamide to halt the α‐synuclein preformed fibrils‐induced damage in nasal epithelial, microglial and dopaminergic neuronal cell lines

open access: yesBrain Pathology, EarlyView.
Omics‐driven drug repositioning reveals pyroxamide as a neuroprotective HDAC1 inhibitor in Parkinson's disease models. Abstract Parkinson's disease (PD) is the second most common neurodegenerative disorder mainly characterized by the degeneration of dopaminergic neurons originating in the substantia nigra (SN) pars compacta and projecting to other ...
Paz Cartas‐Cejudo   +7 more
wiley   +1 more source

Enhanced cytotoxic activity of a bifunctional chimeric protein containing a type 1 ribosome-inactivating protein and a serine protease inhibitor

open access: yes, 2012
Both ribosome-inactivating proteins (RIPs) and plant proteinase inhibitors, belong to protein families known to regulate cellular homeostasis and likely involved in plant defense.
Francesca Tedeschi   +7 more
core   +2 more sources

A Resources Investigation on the Content of Curcin in Jatropha Seed Endosperm Collected from Six Location in Sichuan, Yunnan and Hainan Province

open access: yes四川大学学报. 自然科学版, 2017
The ribosome inactivating protein (curcin) expressed in Jatropha curcas L provides advantages, comparing to prokaryotic expression systems, on the study of protein folding and modification for better development and application of the protein. Therefore,
YANG Qian   +7 more
doaj  

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