Results 31 to 40 of about 31,654 (255)

MAPK Cascade Signaling Is Involved in α-MMC Induced Growth Inhibition of Multiple Myeloma MM.1S Cells via G2 Arrest and Mitochondrial-Pathway-Dependent Apoptosis In Vitro

Pharmaceuticals, 2023
Multiple myeloma is a hematological malignancy characterized by the unrestricted proliferation of plasma cells that secrete monoclonal immunoglobulins in the bone marrow.
Zi-Wei Cai, Ting Ye, Pei-Wen Jiang, Yu-Jiao Liao, Lin Wang, Qing-Liang Zhang, Wen-Qian Du, Min Huang, Ping Yang, Min-Hui Li   +9 more
doaj   +1 more source

Enhancing the efficacy of cytotoxic agents for cancer therapy using photochemical internalisation. [PDF]

, 2015
Photochemical internalisation (PCI) is a technique for improving cellular delivery of certain bioactive agents which are prone to sequestration within endolysosomes.
Adigbli, Adigbli, Arentsen, Baglo, Berg, Berg, Berg, Berg, Berstad, Bodles-Brakhop, Bostad, Bostad, Bull-Hansen, Castano, Castano, Chong, Dietze, Dietze, Elisabeth Olsen, Fretz, Gaware, Gooding, Gottesman, Hirschberg, Høgset, Jørgensen, Kunz, Lai, Lai, Lakshmanan, Lou, Lu, Lund, Mathews, Mroz, Mroz, Norum, Norum, Norum, Norum, Pasparakis, Peng, Peng, Prasmickaite, Reginato, Rosenblum, Selbo, Selbo, Selbo, Selbo, Selbo, Selbo, Selbo, Selbo, Selbo, St Denis, Stratford, Todorova, Vikdal, Wang, Wang, Wang, Weyergang, Weyergang, Woodhams, Xu, Yaghini, Yao, Yip, Zahreddine   +69 more
core   +1 more source

Ribosome inactivating proteins: Enzymes in search of biological function

Anales de la Real Academia Nacional de Farmacia, 2022
Ribosome-inactivating proteins (RIPs) are enzymes (N-glycosidases classified as rRNA N-glycohydrolases, EC 3.2.2.22), mostly of plant origin, but also of bacterial, fungal and algal origin, which cause irreversible inhibition of protein biosynthesis ...
Tomás Girbés Juan, D. Cordoba Díaz
semanticscholar   +1 more source

Impact of Mistletoe Triterpene Acids on the Uptake of Mistletoe Lectin by Cultured Tumor Cells. [PDF]

PLoS ONE, 2016
Complementary treatment possibilities for the therapy of cancer are increasing in demand due to the severe side effects of the standard cytostatics used in the first-line therapy.
Katharina Mulsow, Thomas Enzlein, Catharina Delebinski, Sebastian Jaeger, Georg Seifert, Matthias F Melzig   +5 more
doaj   +1 more source

Viruses and the cellular RNA decay machinery. [PDF]

, 2010
The ability to control cellular and viral gene expression, either globally or selectively, is central to a successful viral infection, and it is also crucial for the host to respond and eradicate pathogens.
Gaglia, Marta, Glaunsinger, Britt
core   +1 more source

Recombinant anti-HIV MAP30, a ribosome inactivating protein: against plant virus and bacteriophage

Scientific Reports, 2023
The ribosome inactivating proteins (RIPs) efficiently decrease the microbial infections in plants. Momordica charantia MAP30 is a type I RIP that has not been investigated against plant viruses or bacteriophages.
Nafiseh Amirzadeh, Ali Moghadam, Ali Niazi, Alireza Afsharifar   +3 more
doaj   +1 more source

Glycotope structures and intramolecular affinity factors of plant lectins for Tn/T antigens [PDF]

, 2011
B
A Babino, AA Jeyaprakash, AM Wu, AM Wu, AM Wu, AM Wu, AM Wu, AM Wu, AM Wu, AM Wu, E Zenteno, EJM Damme Van, GF Springer, GF Springer, GF Springer, GWG Bird, K Puri, KA Kulkarni, KA Kulkarni, M Duk, M Duk, M Sarkar, N Taniguchi, N Vega, R Lotan, R Ravishankar, R Sankaranarayanan, R Zenteno, S Hirohashi, S Tollefsen, SH Itzkowitz, SI Hakomori, SI Hakomori, SI Hakomori, SJ Rinderle, T Singh, T Singh, T Singh, TR Transue, V Piller, W Wang, X Lee, Y Yoda   +42 more
core   +3 more sources

Folding-competent and folding-defective forms of Ricin A chain have different fates following retrotranslocation from the endoplasmic reticulum [PDF]

, 2010
We report that a toxic polypeptide retaining the potential to refold upon dislocation from the endoplasmic reticulum (ER) to the cytosol (ricin A chain; RTA) and a misfolded version that cannot (termed RTAΔ), follow ER-associated degradation (ERAD ...
Shuyu Li, Robert A. Spooner, Stuart C. H. Allen, Christopher P. Guise, Graham Ladds, Tina Schnöder, Manfred J. Schmitt, J. Michael Lord, Lynne M. Roberts, Thomas Sommer, Alcock F., Allen S., Allen S. C., Argent R. H., Arndt V., Bar-Nun S., Barlowe C., Bazirgan O. A., Bellisola G., Biederer T., Bordallo J., Caldwell S. R., Carroll S. M., Carvalho P., Chaddock J. A., Christianson J. C., Deeks E. D., Denic V., Di Cola A., Duden R., Elkabetz Y., Endo Y., Gaber R. F., Gauss R., Ghislain M., Gietz R. D., Gillece P., Graham T. R., Haynes C. M., Hazes B., Heiligenstein S., Heinemeyer W., Hitt R., Jarosch E., Jarosch E., Kaiser C. A., Kawaguchi S., Kim I., Kim Y., Knop M., Kohler A., Lipson C., Lord J. M., Marshall R. S., Mayerhofer P. U., Medicherla B., Metzger M. B., Meusser B., Nakatsukasa K., Nishikawa S. I., Rabinovich E., Rodighiero C., Rouiller I., Rubin D. M., Sharma N., Sikorski R. S., Simpson J. C., Simpson J. C., Spear E. D., Spooner R. A., Spooner R. A., Spooner R. A., Springer S., Taxis C., Vashist S., Vashist S., Vogel J. P., Wesche J., Wilson J. D., Xia Z., Ye Y., Ye Y.   +81 more
core   +1 more source

Effect of transgenic tobacco plant, Nicotiana tabacum expressing ribosome inactivating gene isolated from the bulbs of Dutch iris, Iris hollandica on biological parameters of Myzus nicotianae (Hem.: Aphididea) and Spodoptera exigua (Lep.: Noctuidae) [PDF]

نامه انجمن حشره‌شناسی ایران, 2015
The use of modified crop plants through gene transfer between different plant species plays an important role in pest control programs. We have investigated the insecticidal properties of two lines of tobacco transgenic plant consisting of IRIP ...
Sh. Shahidi-Noghabi
doaj  

The pokeweed leaf mRNA transcriptome and its regulation by jasmonic acid.

Frontiers in Plant Science, 2016
The American pokeweed plant, Phytolacca americana, is recognized for synthesizing pokeweed antiviral protein (PAP), a ribosome inactivating protein (RIP) that inhibits the replication of several plant and animal viruses.
Kira C.M. Neller, Alexander eKlenov, Katalin A. Hudak   +2 more
doaj   +1 more source