Results 11 to 20 of about 1,593,838 (216)

Antifungal Activity of Ribosome-Inactivating Proteins [PDF]

Toxins
The control of crop diseases caused by fungi remains a major problem and there is a need to find effective fungicides that are environmentally friendly.
Rosario Iglesias, Lucía Citores, Claudia C. Gay, José M. Ferreras   +3 more
doaj   +6 more sources

Ribosome-Inactivating and Related Proteins [PDF]

Toxins, 2015
Ribosome-inactivating proteins (RIPs) are toxins that act as N-glycosidases (EC 3.2.2.22). They are mainly produced by plants and classified as type 1 RIPs and type 2 RIPs.
Joachim Schrot, Alexander Weng, Matthias F. Melzig   +2 more
doaj   +7 more sources

Special Issue: Ribosome-Inactivating Proteins—Commemorative Issue in Honor of Professor Fiorenzo Stirpe [PDF]

Molecules, 2017
The family of ribosome-inactivating proteins (RIPs) groups all enzymes (EC.3.2.2.22) with a so-called RIP domain which comprises N-glycosidase activity and enables these proteins to catalytically inactivate ribosomes.[...]
Els J.M. Van Damme
doaj   +4 more sources

The ribosome-inactivating proteins MAP30 and Momordin inhibit SARS-CoV-2 [PDF]

PLoS ONE, 2023
The continuing emergence of SARS-CoV-2 variants has highlighted the need to identify additional points for viral inhibition. Ribosome inactivating proteins (RIPs), such as MAP30 and Momordin which are derived from bitter melon (Momordica charantia), have
Norman R. Watts, Elif Eren, Ira Palmer, Paul L. Huang, Philip Lin Huang, Robert H. Shoemaker, Sylvia Lee-Huang, Paul T. Wingfield   +7 more
doaj   +3 more sources

Engineering of Ribosome-inactivating Proteins for Improving Pharmacological Properties [PDF]

Toxins, 2020
Ribosome-inactivating proteins (RIPs) are N-glycosidases, which depurinate a specific adenine residue in the conserved α-sarcin/ricin loop (α-SRL) of rRNA.
Jia-Qi Lu, Zhen-Ning Zhu, Yong-Tang Zheng, Pang-Chui Shaw   +3 more
doaj   +2 more sources

Ribosome-inactivating proteins: potent poisons and molecular tools. [PDF]

Virulence, 2013
Ribosome-inactivating proteins (RIPs) were first isolated over a century ago and have been shown to be catalytic toxins that irreversibly inactivate protein synthesis.
Walsh MJ, Dodd JE, Hautbergue GM.
europepmc   +5 more sources

Plants Producing Ribosome-Inactivating Proteins in Traditional Medicine [PDF]

Molecules, 2016
Ribosome-inactivating proteins (RIPs) are enzymes that deadenylate nucleic acids and are broadly distributed in the plant kingdom. Many plants that contain RIPs are listed in the pharmacopoeias of folk medicine all over the world, mostly because of their
Letizia Polito, Massimo Bortolotti, Stefania Maiello, Maria Giulia Battelli, Andrea Bolognesi   +4 more
doaj   +2 more sources

Ribosome-Inactivating Proteins of Bougainvillea glabra Uncovered Polymorphism and Active Site Divergence [PDF]

Toxins, 2021
Ribosome-inactivating proteins (RIPs) are toxic proteins that can inhibit protein synthesis. RIPs purified from Bougainvillea have low nonspecific toxicity, showing promise for processing applications in the agricultural and medical fields.
Yihua Lin, Liting Xu, Yanyan Li, Xiaobin Wu, Yijun Liu, Hongmei Zhu, Hantao Zhou   +6 more
doaj   +2 more sources

Functional Assays for Measuring the Catalytic Activity of Ribosome Inactivating Proteins [PDF]

Toxins, 2018
Ribosome-inactivating proteins (RIPs) are potent toxins that inactivate ribosomes by catalytically removing a specific adenine from the α-sarcin/ricin loop (SRL) of the large rRNA.
Yijun Zhou, Xiao-Ping Li, Jennifer N. Kahn, Nilgun E. Tumer   +3 more
doaj   +2 more sources

Ribosomal RNA N-glycosylase Activity Assay of Ribosome-inactivating Proteins [PDF]

Bio-Protocol, 2017
Ribosome-inactivating proteins (RIPs) are enzymes that irreversibly inactivate ribosomes as a consequence of their N-glycosylase (EC 3.2.2.22) activity. The enzyme cleaves the N-glycosidic bond between the adenine No.
José Ferreras, Lucía Citores, José Ferreras   +2 more
doaj   +2 more sources