Results 111 to 120 of about 110,963 (265)

Small‐Molecule Activation of mRNA Translation by Click‐to‐Release Reaction in Cells

open access: yesAngewandte Chemie International Edition, EarlyView.
A new method to control mRNA activity using bioorthogonal click‐to‐release reactions is presented. The 5′ cap is modified with a trans‐cyclooctene (TCO) that quickly reacts with hydroxyaryl‐tetrazines and efficiently releases the native cap 0. TCO‐capped mRNAs are initially translationally inactive but can be activated with non‐toxic, cell‐permeable ...
Tess Vosman   +5 more
wiley   +1 more source

Bridging single-molecule and genome-wide studies of cellular mRNA translation. [PDF]

open access: yesRNA
Koch A   +5 more
europepmc   +1 more source

Time Resolution in Cryo-EM Using a Novel PDMS-Based Microfluidic Chip Assembly and Its Application to the Study of HflX-Mediated Ribosome Recycling

open access: green, 2023
Sayan Bhattacharjee   +6 more
openalex   +1 more source

Gonadal development in scorpion mud‐turtles, Kinosternon scorpioides, in a controlled environment

open access: yesThe Anatomical Record, EarlyView.
Stage 20 was identified as the critical point for gonadal differentiation in Kinosternon scorpioides, providing key insights into sex determination. These findings enhance conservation strategies by supporting reproductive management and population viability in both in situ and ex situ programs. Abstract Research on gonadal development including sexual
Brenda Braga   +4 more
wiley   +1 more source

Mechanism of ribosome stalling by the AMD1 C-terminal tail arrest peptide. [PDF]

open access: yesSci Adv
Maldosevic E   +6 more
europepmc   +1 more source

Developmental Characteristics of the Embryonic Liver Tissue and Long‐Term Culture of Primary Hepatocytes in Duck

open access: yesAnimal Research and One Health, EarlyView.
Liver development was investigated at different embryonic ages (EAs). Furthermore, numerous hepatocyte media were formulated and evaluated. These results could elaborate the developmental characteristics of duck liver tissue and determine the most suitable medium for the proliferation and characteristic maintenance of hepatocytes in vitro, which would ...
Jie Wei   +7 more
wiley   +1 more source

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