Results 151 to 160 of about 254,640 (401)
In this paper we motivate and develop a model of gene expression for the purpose of studying the interaction between synthetic gene circuits and the chassis cell within which they are in- serted.
Algar, Rhys, Ellis, Tom, Stan, Guy-Bart
core
Template-directed biopolymerization: tape-copying Turing machines
DNA, RNA and proteins are among the most important macromolecules in a living cell. These molecules are polymerized by molecular machines. These natural nano-machines polymerize such macromolecules, adding one monomer at a time, using another linear ...
Chowdhury, Debashish, Sharma, Ajeet K.
core +1 more source
Citropin 1.3 is an antimicrobial peptide derived from amphibians that forms amyloid structures. Here, the structural and functional properties of citropin 1.3 are characterized. Using high‐resolution imaging approaches, a variety of canonical and undescribed fibril morphologies are identified.
Fabio Strati+8 more
wiley +1 more source
A New Mechanism for Ribosome Rescue Can Recruit RF1 or RF2 to Nonstop Ribosomes
Bacterial ribosomes frequently translate to the 3′ end of an mRNA without terminating at an in-frame stop codon. In all bacteria studied to date, these “nonstop” ribosomes are rescued using trans-translation.
Tyler D. P. Goralski+2 more
doaj +1 more source
Organization of Ribosomes and Nucleoids in Escherichia coli Cells during Growth and in Quiescence*
Background: We studied ribosome and nucleoid distribution in Escherichia coli under growth and quiescence. Results: Spatially segregated ribosomes and nucleoids show drastically altered distribution in stationary phase or when treated with drugs ...
Qian Chai+6 more
semanticscholar +1 more source
Ribosomal proteins and the assembly of ribosomes in eukaryotes [PDF]
J R Warner, S A Udem, A Kumar, R S Wu
openaire +4 more sources
In intestinal stem cells (ISCs), Snord15b associates with Ilf2 to recruit splicing factors for alternative splicing of Btrc mRNA, leading to the generation of short Btrc. This short Btrc fails to form a functional E3 ubiquitin ligase complex for β‐catenin ubiquitination and degradation.
Yuwei Xu+13 more
wiley +1 more source
FA directly binds to residue H378 of DDX6 and promotes its interaction with HSC70, leading to CMA degradation of DDX6, thereby impairing GSK‐3β/β‐catenin signaling, inhibiting ABC transporter proteins, and enhancing chemosensitivity. Abstract ABC transporter protein‐mediated drug efflux is a significant contributor to induced resistance in breast ...
Xiaxia Fan+5 more
wiley +1 more source
The Binding of Peptidyl‐tRNA and Acylaminoacyl‐tRNA to E. coli Ribosomes [PDF]
Natalia Sánchez de Groot+2 more
openalex +1 more source