Results 31 to 40 of about 254,640 (401)

Microtubule-dependent ribosome localization in C. elegans neurons. [PDF]

, 2017
Subcellular localization of ribosomes defines the location and capacity for protein synthesis. Methods for in vivo visualizing ribosomes in multicellular organisms are desirable in mechanistic investigations of the cell biology of ribosome dynamics. Here,
Ellisman, Mark H, Goncharov, Alexandr, Jin, Yishi, Noma, Kentaro   +3 more
core   +1 more source

Collided ribosomes form a unique structural interface to induce Hel2‐driven quality control pathways

EMBO Journal, 2019
Ribosome stalling triggers quality control pathways targeting the mRNA (NGD: no‐go decay) and the nascent polypeptide (RQC: ribosome‐associated quality control). RQC requires Hel2‐dependent uS10 ubiquitination and the RQT complex in yeast.
Ken Ikeuchi, P. Tesina, Y. Matsuo, Takato Sugiyama, Jingdong Cheng, Y. Saeki, Keiji Tanaka, T. Becker, R. Beckmann, T. Inada   +9 more
semanticscholar   +1 more source

Ribosomal proteins: functions beyond the ribosome [PDF]

Journal of Molecular Cell Biology, 2015
Although ribosomal proteins are known for playing an essential role in ribosome assembly and protein translation, their ribosome-independent functions have also been greatly appreciated. Over the past decade, more than a dozen of ribosomal proteins have been found to activate the tumor suppressor p53 pathway in response to ribosomal stress. In addition,
Peng Liao, Jun-Ming Liao, Xiang Zhou, Hua Lu, Wenjuan Liao   +4 more
openaire   +3 more sources

Regulation of Translation by Lysine Acetylation in Escherichia coli

mBio, 2022
Nε-lysine acetylation is a common posttranslational modification observed in diverse species of bacteria. Aside from a few central metabolic enzymes and transcription factors, little is known about how this posttranslational modification regulates ...
Sarah C. Feid, Hanna E. Walukiewicz, Xiaoyi Wang, Ernesto S. Nakayasu, Christopher V. Rao, Alan J. Wolfe   +5 more
doaj   +1 more source

Transport of Cytoplasmically Synthesized Proteins into the Mitochondria in a Cell Free System from Neurospora crassa [PDF]

, 1977
Synthesis and transport of mitochondrial proteins were followed in a cell-free homogenate of Neurospora crassa in which mitochondrial translation was inhibited. Proteins synthesized on cytoplasmic ribosomes are transferred into the mitochondrial fraction.
Andrews T. M., Bingham R. W., Blair G. E., Davidian N. M., Dobberstein B., Dolken G., Gaitskhoki V. S., Godinot C., Gonzalez-Cadavid N. F., Gonzalez-Cadavid N. F., Grollmann A. P., Hallermayer G., Kadenbach B., Kadenbach B., Kadenbach B., Kellems R. E., Kellems R. E., Kellems R. E., Kellems R. E., Marra E., Milstein C., Morris A., O'Brien R. L., Pfaff E., Redman C. M., Shore G. C., Takanami M., Tata J. R., Weiss H., Wojtczak L., Wojtczak L.   +30 more
core   +1 more source

A Structurally Characterized Staphylococcus aureus Evolutionary Escape Route from Treatment with the Antibiotic Linezolid

Microbiology Spectrum, 2022
Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen that presents great health concerns. Treatment requires the use of last-line antibiotics, such as members of the oxazolidinone family, of which linezolid is the first member to ...
Laura Perlaza-Jiménez, Kher-Shing Tan, Sarah J. Piper, Rachel M. Johnson, Rebecca S. Bamert, Christopher J. Stubenrauch, Alexander Wright, David Lupton, Trevor Lithgow, Matthew J. Belousoff   +9 more
doaj   +1 more source

Puromycin Sensitivity of Ribosomal Label after Incorporation of 14C-Labelled Amino Acids into Isolated Mitochondria from Neurospora crassa [PDF]

, 1969
Radioactive amino acids were incorporated into isolated mitochondria from Neurospora crassa. Then the mitochondrial ribosomes were isolated and submitted to density gradient centrifugation. A preferential labelling of polysomes was observed.
Dingman C. W., Dingman C. W., Kuntzel H., Kuntzel H., Luck D. J. L., Neupert W., Noll H., Peacock A. C., Rifkin M. R.   +8 more
core   +2 more sources

Crystal Structure of the 23S rRNA Fragment Specific to r-Protein L1 and Designed Model of the Ribosomal L1 Stalk from Haloarcula marismortui

Crystals, 2017
The crystal structure of the 92-nucleotide L1-specific fragment of 23S rRNA from Haloarcula marismortui (Hma) has been determined at 3.3 Å resolution.
Azat Gabdulkhakov, Svetlana Tishchenko, Alisa Mikhaylina, Maria Garber, Natalia Nevskaya, Stanislav Nikonov   +5 more
doaj   +1 more source

The 73 S ribosome of Neurospora crassa is the native mitochondrial ribosome [PDF]

, 1977
The effect of the inclusion of EDTA and of heparin, in media used in the isolation of mitochondria, on the mitochindrial previous termribosomenext term has been investigated. 1. 1.
Adelmann, Alberghina, Avadhani, Datema, Grivell, Hallermayer, Kellems, Kroon, Küntzel, Leaver, Leaver, Lizardi, Loening, Monro, Neupert, Neupert, O'Brien, Palmiter, Pene, Schmitt, Taylor, van den Bogert, Vogel, von Rücker, Weiss   +24 more
core   +1 more source

Uncovering the assembly pathway of human ribosomes and its emerging links to disease

EMBO Journal, 2019
The essential cellular process of ribosome biogenesis is at the nexus of various signalling pathways that coordinate protein synthesis with cellular growth and proliferation.
K. Bohnsack, M. Bohnsack
semanticscholar   +1 more source