Results 31 to 40 of about 179,543 (360)
Ribosomal Biogenesis and Heterogeneity in Development, Disease, and Aging
Although reported in the literature, ribosome heterogeneity is a phenomenon whose extent and implications in cell and organismal biology is not fully appreciated.
Rowshan Ara Islam, Charalampos Rallis
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Transcriptome-wide sites of collided ribosomes reveal principles of translational pausing
Translation initiation is considered overall rate-limiting for protein biosynthesis, whereas the impact of non-uniform ribosomal elongation rates is largely unknown. Using a modified ribosome profiling protocol based on footprints from two closely packed
A. B. Arpat +5 more
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Nuclear 80S Ribosomes Present Across the Stages of Cell Cycle in Drosophila Melanogaster Cells
Nuclear translation has been a subject of controversy between scientists for over 5 decades. Despite the existence of evidence to the contrary, most biologists agree that translation exclusively takes place in the cytoplasm of eukaryotes.
Akilu Abdullahi, Saverio Brogna
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Isolation of biologically active cell components from multicellular eukaryotic organisms often poses difficult challenges such as low yields and inability to retain the integrity and functionality of the purified compound. We previously identified a cap-
Vera Aleksey Stupina +1 more
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Diaphorin is a polyketide produced by “Candidatus Profftella armatura” (Gammaproteobacteria: Burkholderiales), an obligate symbiont of a devastating agricultural pest, the Asian citrus psyllid Diaphorina citri (Hemiptera: Psyllidae).
Rena Takasu +2 more
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The Impact of Oxidative Stress on Ribosomes: From Injury to Regulation
The ribosome is a complex ribonucleoprotein-based molecular machine that orchestrates protein synthesis in the cell. Both ribosomal RNA and ribosomal proteins can be chemically modified by reactive oxygen species, which may alter the ribosome′s functions
N. Shcherbik, D. Pestov
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Ribosomes, Ribosomal Subunits and Ribosomal Proteins from Myxococcus xanthus [PDF]
SUMMARY: Polyribosomes and ribosomes were isolated from vegetative Myxococcus xanthus FB and myxospores. The sedimentation coefficients of monoribosomes and ribosomal subunits were the same as those for equivalent particles from Escherichia coli. Conditions for the dissociation of the ribosomes and the unfolding of the subunits (in strong salt or very ...
H. A. FOSTER, J. H. PARISH
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It was found that spermidine (5mM) delivered to wheat seedlings through their roots prior to water stress affected the state of polysomes and ribosomes under water stress conditions, which was manifested in stabilization of 80 S ribosomes and in ...
Halina Gniazdowska-Skoczek +2 more
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Does functional specialization of ribosomes really exist?
It has recently become clear that ribosomes are much more heterogeneous than previously thought, with diversity arising from rRNA sequence and modifications, ribosomal protein (RP) content and posttranslational modifications (PTMs), as well as bound ...
Max B. Ferretti, K. Karbstein
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Ribosomal proteins (RPs) are mostly derived from the energy-consuming enzyme families such as ATP-dependent RNA helicases, AAA-ATPases, GTPases and kinases, and are important structural components of the ribosome, which is a supramolecular ...
Abu Musa Md Talimur Reza, Yu-Guo Yuan
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