Results 31 to 40 of about 239,527 (406)
The mitochondrial ribosome and ribosomal RNA of the chick [PDF]
FEBS Letters, 1971 Reports have appeared on large molecular weight RNAs associated with the mitochondria of higher organisms. These include HeLa cells [ 1 ] , BHK-2 1 cells [2] , mouse L-cells [3,4] , rat liver [4, S] and Xenopus ovary [6] . This RNA consists of two predominant species found to be 17 S and 13 S by sedimentation [2, 31 .
Terence H. Rabbitts, T.S. Work
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Ribosome Biogenesis and Cancer: Overview on Ribosomal Proteins [PDF]
International Journal of Molecular Sciences, 2021 Cytosolic ribosomes (cytoribosomes) are macromolecular ribonucleoprotein complexes that are assembled from ribosomal RNA and ribosomal proteins, which are essential for protein biosynthesis. Mitochondrial ribosomes (mitoribosomes) perform translation of the proteins essential for the oxidative phosphorylation system. The biogenesis of cytoribosomes and
Pecoraro Annalisa +3 more
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Modeling Cell-Free Protein Synthesis Systems—Approaches and Applications
Frontiers in Bioengineering and Biotechnology, 2020 In vitro systems are ideal setups to investigate the basic principles of biochemical reactions and subsequently the bricks of life. Cell-free protein synthesis (CFPS) systems mimic the transcription and translation processes of whole cells in a ...
Jan Müller +2 more
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Structure of Gcn1 bound to stalled and colliding 80S ribosomes
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance There is growing evidence that collisions between ribosomes represent a cellular signal for activating multiple stress pathways, such as ribosome-associated quality control (RQC), the ribotoxic stress response, and the integrated stress ...
A. Pochopien +6 more
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Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes
bioRxiv, 2020 Cells adjust to nutrient deprivation by reversible translational shut down. This is accompanied by maintaining inactive ribosomes in a hibernation state, where they are bound by proteins with inhibitory and protective functions.
J. N. Wells +9 more
semanticscholar +1 more source
Frontiers in Cell and Developmental Biology, 2019 Mitochondria exert their many functions through a repertoire of hundreds of proteins. The vast majority of these proteins are encoded in the nuclear genome, translated in the cytosol and imported into the mitochondria. Current models, derived mainly from
Dikla Vardi-Oknin +2 more
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Acta Societatis Botanicorum Poloniae, 2014 It was found that spermidine (5mM) delivered to wheat seedlings through their roots prior to water stress affected the state of polysomes and ribosomes under water stress conditions, which was manifested in stabilization of 80 S ribosomes and in ...
Halina Gniazdowska-Skoczek +2 more
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Analyzing ribosome remodeling in health and disease [PDF]
PROTEOMICS (2020), 2020 regulation largely unexplored, in part due to methodological limitations. Indeed, we review evidence demonstrating that commonly used methods, such as transcriptomics, are inadequate because the variability in mRNAs coding for ribosomal proteins (RP) does not necessarily correspond to RP variability.
arxiv +1 more source
Mitochondrial Translation Products before and after Integration into the Mitochondrial Membrane in Neurospora crassa [PDF]
, 1972 # 1. Nascent translation products on mitochondrial ribosomes were selectively labeled in vivo in the presence of cycloheximide with radioactive leucine. They were isolated together with the ribosomes. # 2.
Michel, Rainer, Neupert, Walter
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Acta Societatis Botanicorum Poloniae, 2014 Grains of winter rye harvested in 1976, 1978, 1982 and 1984 were studied. Free and membrane-bound polyribosomes were isolated from embryos of imbibing and germinating grains.
Kazimierz Zalewski
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