Results 91 to 100 of about 7,522 (226)
Postepy biochemii, 2005 Riboswitches are RNA structures able to bind small molecules and regulate gene expression at both, transcriptional and translational level. They are present in a wide variety of bacterial species. In Bacillus subtilis more than 2% of the genome is regulated by riboswitches. Metabolite binding is highly specific and can be provided in cooperative manner.
Katarzyna, Bugała +4 more
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Programming Next‐Generation Synthetic Biosensors by Genetic Circuit Design
Advanced Science, Volume 13, Issue 14, 9 March 2026.Synthetic biology enables genetic circuit‐based biosensing to detect diverse targets, process signals, and transduce them into readable outputs or intracellular regulatory activities. However, field deployment and real‐world application of such synthetic biosensors face considerable challenges in sensitivity, specificity, speed, stability, and ...
Yuanli Gao +4 more
wiley +1 more source
Synthetic Cells on Demand: From Molecular Stimuli to Cellular Functions
ChemSystemsChem, Volume 8, Issue 2, March 2026.ABSTRACT Synthetic cells constructed via bottom‐up approaches using lipid or polymer vesicles have become essential tools for mimicking cellular functions and studying synthetic biological systems. These vesicles can undergo morphological changes and trigger internal reactions in response to external stimuli, such as osmotic pressure, temperature, pH ...
Masato Suzuki, Koki Kamiya
wiley +1 more source
Novel TPP-riboswitch activators bypass metabolic enzyme dependency
Frontiers in Chemistry, 2014 Riboswitches are conserved regions within mRNA molecules that bind specific metabolites and regulate gene expression. TPP-riboswitches, which respond to thiamine pyrophosphate (TPP), are involved in the regulation of thiamine metabolism in numerous ...
Günter eMayer +3 more
doaj +1 more source
The Structure of the Guanidine-II Riboswitch
Cell Chemical Biology, 2017 The guanidine-II (mini-ykkC) riboswitch is the smallest of the guanidine-responsive riboswitches, comprising two stem loops of similar sequence. We have solved high-resolution crystal structures of both stem loops for the riboswitch from Gloeobacter violaceus. The stem loops have a strong propensity to dimerize by intimate loop-loop interaction.
Huang, Lin +2 more
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Development of a Xylose-Inducible Promoter and Riboswitch Combination System for Manipulating Gene Expression in Fusobacterium nucleatum [PDF]
, 2023 G C Bibek +4 more
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Tuning Strand Displacement Kinetics Enables Programmable ZTP Riboswitch Dynamic Range in vivo [PDF]
, 2022 David Z. Bushhouse, Julius B. Lucks
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Communications BiologyRiboswitches regulate gene expression by modulating their structure upon metabolite binding. These RNA orchestrate several layers of regulation to achieve genetic control.
Jonathan P. Grondin +10 more
doaj +1 more source
Atomistic basis for the on-off signaling mechanism in SAM-II riboswitch [PDF]
, 2009 James Kelley, Donald Hamelberg
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Abundance and functional diversity of riboswitches in microbial communities
BMC Genomics, 2007 Background Several recently completed large-scale enviromental sequencing projects produced a large amount of genetic information about microbial communities ('metagenomes') which is not biased towards cultured organisms.
Gelfand Mikhail S +2 more
doaj +1 more source