Results 81 to 90 of about 7,960 (219)

Riboswitches as hormone receptors: hypothetical cytokinin-binding riboswitches in Arabidopsis thaliana [PDF]

open access: yesBiology Direct, 2010
Riboswitches are mRNA elements that change conformation when bound to small molecules. They are known to be key regulators of biosynthetic pathways in both prokaryotes and eukaryotes.The hypothesis presented here is that riboswitches function as receptors in hormone perception.
Downes Brian, Grojean Jeremy
openaire   +3 more sources

Aminoglycoside riboswitch control of the expression of integron associated aminoglycoside resistance adenyltransferases

open access: yesVirulence, 2020
The proliferation of antibiotic resistance has its origins in horizontal gene transfer. The class 1 integrons mediate gene transfer by assimilating antibiotic-resistance genes through site-specific recombination.
Jun Zhang   +8 more
doaj   +1 more source

CIA5 and its interacting metal‐binding GTPase ZNG3 are degraded by the proteasome in Zn deficiency

open access: yesThe Plant Journal, Volume 127, Issue 1, July 2026.
SUMMARY Carbon and zinc (Zn) metabolism are tightly connected in phototrophs, as carbonic anhydrases critical for CO2 assimilation are highly abundant Zn enzymes. The eukaryotic green alga Chlamydomonas (Chlamydomonas reinhardtii) maintains efficient phototrophic growth in ambient or low CO2 environments by establishing a carbon concentrating mechanism
George Kusi‐Appiah   +5 more
wiley   +1 more source

RNA folding kinetics control riboswitch sensitivity in vivo

open access: yesNature Communications
Riboswitches are ligand-responsive gene-regulatory RNA elements that perform key roles in maintaining cellular homeostasis. Understanding how riboswitch sensitivity to ligand (EC50) is controlled is critical to explain how highly conserved aptamer ...
David Z. Bushhouse   +2 more
doaj   +1 more source

Using a Riboswitch Sensor to Detect Co2+/Ni2+ Transport in E. coli

open access: yesFrontiers in Chemistry, 2021
Intracellular concentrations of essential mental ions must be tightly maintained to avoid metal deprivation and toxicity. However, their levels in cells are still difficult to monitor. In this report, the combination of a Co2+Ni2+-specific riboswitch and
Xiaoying Wang   +3 more
doaj   +1 more source

Carba-sugars Activate the glmS-Riboswitch of Staphylococcus aureus [PDF]

open access: yes, 2011
The glmS-riboswitch is unique among riboswitch families as it represents a metabolite-dependent ribozyme that undergoes self-cleavage upon recognition of glucosamin-6-phosphate.
Günter Mayer   +7 more
core   +1 more source

Identification of potential riboswitch elements in Homo sapiens mRNA 5'UTR sequences using positive-unlabeled machine learning.

open access: yesPLoS ONE
Riboswitches are a class of noncoding RNA structures that interact with target ligands to cause a conformational change that can then execute some regulatory purpose within the cell.
William S Raymond   +2 more
doaj   +1 more source

Synthesis of O6-alkylated preQ1 derivatives

open access: yesBeilstein Journal of Organic Chemistry, 2021
A naturally occurring riboswitch can utilize 7-aminomethyl-O6-methyl-7-deazaguanine (m6preQ1) as cofactor for methyl group transfer resulting in cytosine methylation.
Laurin Flemmich   +2 more
doaj   +1 more source

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

open access: yesAngewandte Chemie International Edition, Volume 65, Issue 23, 1 June 2026.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl   +1 more
wiley   +1 more source

The long and the short of riboswitches [PDF]

open access: yesCurrent Opinion in Structural Biology, 2009
Regulatory mRNA elements or riboswitches specifically control the expression of a large number of genes in response to various cellular metabolites. The basis for selectivity of regulation is programmed in the evolutionarily conserved metabolite-sensing regions of riboswitches, which display a plethora of sequence and structural variants.
openaire   +2 more sources

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