Results 101 to 110 of about 7,522 (226)

Structural analysis of a class III preQ 1 riboswitch reveals an aptamer distant from a ribosome-binding site regulated by fast dynamics [PDF]

open access: bronze, 2015
Joseph A. Liberman   +9 more
openalex   +1 more source

Mechanistic analysis of Riboswitch Ligand interactions provides insights into pharmacological control over gene expression

open access: yesNature Communications
Riboswitches are structured RNA elements that regulate gene expression upon binding to small molecule ligands. Understanding the mechanisms by which small molecules impact riboswitch activity is key to developing potent, selective ligands for these and ...
Shaifaly Parmar   +12 more
doaj   +1 more source

Ligand-Directed Conformational Dynamics of the Adenine-Sensing Riboswitch Thermostat [PDF]

open access: bronze, 2017
Sven Warhaut   +6 more
openalex   +1 more source

Ligand-dependent tRNA processing by a rationally designed RNase P riboswitch [PDF]

open access: gold, 2020
Anna Ender   +5 more
openalex   +1 more source

Scaffold-enabled high-resolution cryo-EM structure determination of RNA

open access: yesNature Communications
Cryo-EM structure determination of protein-free RNAs has remained difficult with most attempts yielding low to moderate resolution and lacking nucleotide-level detail.
Daniel B. Haack   +5 more
doaj   +1 more source

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