Results 101 to 110 of about 7,960 (219)
Riboswitch RNAs whose abundance is dependent on RNase Y expression. [PDF]
Transcriptional profiles of a selection of six riboswitches controlling the expression of the downstream gene via transcriptional attenuation are shown. In all cases the terminated leader transcript accumulates strongly when strain SSB447 (Pspac-rny) is ...
Anna Rocca (104608) +5 more
core +1 more source
Biological Degradation of Phthalates: From Bioremediation to Plastic Waste Valorization
Phthalic acid isomers play a key role in the plastics industry, but pose significant environmental and health concerns. This review explores the microbial biodegradation of phthalates and their esters, focusing on bacterial enzymes, catabolic pathways, and cellular uptake mechanisms of phthalates.
Marco A. Pereyra‐Camacho, Isabel Pardo
wiley +1 more source
The structure of the SAM/SAH-binding riboswitch [PDF]
S-adenosylmethionine (SAM) is a central metabolite since it is used as a methyl group donor in many different biochemical reactions. Many bacteria control intracellular SAM concentrations using riboswitch-based mechanisms.
Weickhmann, A. Katharina +9 more
core +1 more source
Small Molecule‐Based Conditional Gene Regulation: Advances and Applications
The precise, temporal, and reversible control of gene expression using small molecule ligands is crucial for understanding complex cellular functions and is rapidly advancing the field of synthetic biology. Small molecule‐mediated conditional gene regulation has widespread applications, including bio‐manufacturing, cellular reprogramming, gene therapy,
Mohd Afaque Ansari +3 more
wiley +1 more source
Structural, Functional, and Taxonomic Diversity of Three PreQ1 Riboswitch Classes [PDF]
SummaryPreviously, two riboswitch classes have been identified that sense and respond to the hypermodified nucleobase called prequeuosine1 (preQ1).
McCown, Phillip J. +3 more
core +1 more source
The return of metabolism: biochemistry and physiology of glycolysis
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning +19 more
wiley +1 more source
Riboswitches are RNA structures able to bind small molecules and regulate gene expression at both, transcriptional and translational level. They are present in a wide variety of bacterial species. In Bacillus subtilis more than 2% of the genome is regulated by riboswitches. Metabolite binding is highly specific and can be provided in cooperative manner.
Katarzyna, Bugała +4 more
openaire +1 more source
Dynamics Correlation Network for Allosteric Switching of PreQ1 Riboswitch [PDF]
Riboswitches are a class of metabolism control elements mostly found in bacteria. Due to their fundamental importance in bacteria gene regulation, riboswitches have been proposed as antibacterial drug targets.
Zhang, Jinmai +5 more
core +1 more source
Structural Basis for Molecular Discrimination by a 3′,3′-cGAMP Sensing Riboswitch
Cyclic dinucleotides are second messengers that target the adaptor STING and stimulate the innate immune response in mammals. Besides protein receptors, there are bacterial riboswitches that selectively recognize cyclic dinucleotides.
Aiming Ren +6 more
doaj +1 more source

