Results 71 to 80 of about 7,522 (226)
Using a Riboswitch Sensor to Detect Co2+/Ni2+ Transport in E. coli
Frontiers in Chemistry, 2021 Intracellular concentrations of essential mental ions must be tightly maintained to avoid metal deprivation and toxicity. However, their levels in cells are still difficult to monitor. In this report, the combination of a Co2+Ni2+-specific riboswitch and
Xiaoying Wang +3 more
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PLoS ONERiboswitches are a class of noncoding RNA structures that interact with target ligands to cause a conformational change that can then execute some regulatory purpose within the cell.
William S Raymond +2 more
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Synthesis of O6-alkylated preQ1 derivatives
Beilstein Journal of Organic Chemistry, 2021 A naturally occurring riboswitch can utilize 7-aminomethyl-O6-methyl-7-deazaguanine (m6preQ1) as cofactor for methyl group transfer resulting in cytosine methylation.
Laurin Flemmich +2 more
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The long and the short of riboswitches [PDF]
Current Opinion in Structural Biology, 2009 Regulatory mRNA elements or riboswitches specifically control the expression of a large number of genes in response to various cellular metabolites. The basis for selectivity of regulation is programmed in the evolutionarily conserved metabolite-sensing regions of riboswitches, which display a plethora of sequence and structural variants.
openaire +2 more sources
Nature Communications, 2023 Cell-free genetically encoded biosensors have been developed to detect small molecules and nucleic acids, but they have yet to be reliably engineered to detect proteins.
Grace E. Vezeau +2 more
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ChemPlusChem, Volume 91, Issue 5, May 2026.We established light‐ and bioluminescence‐responsive systems that allow reversible conjugation and dissociation of proteins on the inner leaflet of asymmetric lipid–amphiphilic protein hybrid vesicles. These systems provide a versatile platform for precise spatiotemporal regulation and bioluminescence‐triggered protein release within synthetic vesicles.
Masato Suzuki, Koki Kamiya
wiley +1 more source
Evaluating riboswitch optimality
, 2019 Riboswitches are RNA elements that recognize diverse chemical and biomolecular inputs, and transduce this recognition process to genetic, fluorescent, and other engineered outputs using RNA conformational changes. These systems are pervasive in cellular biology and are a promising biotechnology with applications in genetic regulation and biosensing ...
Hannah, Wayment-Steele +3 more
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Riboswitches and the RNA World [PDF]
Cold Spring Harbor Perspectives in Biology, 2010 Riboswitches are structured noncoding RNA domains that selectively bind metabolites and control gene expression (Mandal and Breaker 2004a; Coppins et al. 2007; Roth and Breaker 2009). Nearly all examples of the known riboswitches reside in noncoding regions of messenger RNAs where they control transcription or translation.
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Design principles for riboswitch function. [PDF]
PLoS Computational Biology, 2009 Scientific and technological advances that enable the tuning of integrated regulatory components to match network and system requirements are critical to reliably control the function of biological systems. RNA provides a promising building block for the
Chase L Beisel, Christina D Smolke
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A Synthetic Riboswitch to Regulate Haloarchaeal Gene Expression
Frontiers in Microbiology, 2021 In recent years, synthetic riboswitches have become increasingly important to construct genetic circuits in all three domains of life. In bacteria, synthetic translational riboswitches are often employed that modulate gene expression by masking the Shine-
Johannes Born +4 more
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