Results 111 to 120 of about 44,034 (296)

The review of recent advances in fish genetics and biotechnology [PDF]

open access: yes, 2012
Great advances have been, and are being made in our knowledge of the genetics and molecular biology (including genomics, proteomics and structural biology).
Mgbabu , Christopher Nwokwa
core  

Probing complex RNA structures by mechanical force

open access: yes, 2003
RNA secondary structures of increasing complexity are probed combining single molecule stretching experiments and stochastic unfolding/refolding simulations. We find that force-induced unfolding pathways cannot usually be interpretated by solely invoking
A. Xayaphoummine   +36 more
core   +3 more sources

Short-term sequence evolution and vertical inheritance of the Naegleria twin-ribozyme group I intron

open access: yesBMC Evolutionary Biology, 2006
Background Ribosomal DNA of several species of the free-living Naegleria amoeba harbors an optional group I intron within the nuclear small subunit ribosomal RNA gene.
De Jonckheere Johan F   +3 more
doaj   +1 more source

A Cross-chiral RNA Polymerase Ribozyme

open access: yesNature, 2014
Thirty years ago it was shown that the non-enzymatic, template-directed polymerization of activated mononucleotides proceeds readily in a homochiral system, but is severely inhibited by the presence of the opposing enantiomer. This finding poses a severe
Jonathan T. Sczepanski, G. F. Joyce
semanticscholar   +1 more source

Metal-ion binding and metal-ion induced folding of the adenine-sensing riboswitch aptamer domain [PDF]

open access: yes, 2010
Divalent cations are important in the folding and stabilization of complex RNA structures. The adenine-sensing riboswitch controls the expression of mRNAs for proteins involved in purine metabolism by directly sensing intracellular adenine levels ...
Noeske, Jonas   +2 more
core  

Complete RNA inverse folding: computational design of functional hammerhead ribozymes

open access: yes, 2014
Nanotechnology and synthetic biology currently constitute one of the most innovative, interdisciplinary fields of research, poised to radically transform society in the 21st century. This paper concerns the synthetic design of ribonucleic acid molecules,
Clote, Peter   +5 more
core   +1 more source

Automated design of hammerhead ribozymes and validation by targeting the PABPN1 gene transcript [PDF]

open access: gold, 2015
Nawwaf Kharma   +9 more
openalex   +1 more source

Restoration of Retinoid Sensitivity by MDR1 Ribozymes in Retinoic Acid–Resistant Myeloid Leukemic Cells [PDF]

open access: bronze, 1998
Hiromichi Matsushita   +9 more
openalex   +1 more source

A ribozyme that triphosphorylates RNA 5′-hydroxyl groups

open access: yesNucleic Acids Research, 2014
The RNA world hypothesis describes a stage in the early evolution of life in which RNA served as genome and as the only genome-encoded catalyst. To test whether RNA world organisms could have used cyclic trimetaphosphate as an energy source, we developed
J. Moretti, U. F. Müller
semanticscholar   +1 more source

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