Results 91 to 100 of about 18,960 (170)
The Hammerhead Ribozyme Catalyzes the Deglycosylation of 2‘-Mercaptocytidine
, 2016 The Hammerhead Ribozyme Catalyzes the Deglycosylation of 2 ...
Jason P. Schwans (1320693) +2 more
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Trans-splicing with the group I intron ribozyme from Azoarcus [PDF]
, 2014 Group I introns are ribozymes (catalytic RNAs) that excise themselves from RNA primary transcripts by catalyzing two successive transesterification reactions.
Dolan, Gregory F, Müller, Ulrich F
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Short-term sequence evolution and vertical inheritance of the
BMC Evolutionary Biology, 2006 Background Ribosomal DNA of several species of the free-living Naegleria amoeba harbors an optional group I intron within the nuclear small subunit ribosomal RNA gene.
De Jonckheere Johan F +3 more
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The structure and active site of the Varkud satellite ribozyme
, 2002 The Varkud satellite ribozyme is the largest of the small nucleolytic ribozymes, and the only one for which there is no crystal structure. It can be divided into a trans-acting ribozyme, consisting of five helices organized by two three-way helical ...
Lilley, D. M.J.; id_orcid +2 more
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2CATPase enhances hammerhead ribozyme activity.
, 2015 (A) Schematic illustrations of the sequences and secondary structures of hammerhead ribozyme (purple) and its substrate RNA (red and blue). The ribozyme is a 58-nt unlabeled RNA synthesized by T7 RNA polymerase, and the 28-nt RNA substrate was ...
Hongjie Xia (513366) +12 more
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Autocatalytic assembly of a chimeric aminoacyl-RNA synthetase ribozyme [PDF]
Autocatalytic reactions driving the self-assembly of biological polymers are important for the origin of life, yet few experimental examples of such reactions exist.
Todisco, Marco +3 more
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A hammerhead ribozyme selects mechanically stable conformations for catalysis against viral RNA
Communications BiologyRibozymes, widely found in prokaryotes and eukaryotes, target nucleic acids and can be engineered as biotechnical tools or for gene regulation or immune therapy. Among them, hammerhead is the smallest and best characterized ribozyme.
Man Lu +11 more
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, 2016 Ribozyme Mechanism Revisited: Evidence against Direct Coordination of a Mg2+ Ion with the pro-R Oxygen of the Scissile Phosphate in the Transition State of a Hammerhead Ribozyme-Catalyzed ...
Kazunari Taira (59649) +3 more
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Identification of ribozyme mutations that increase chloramphenicol resistance.
, 2014 A, Growth rates of E.coli cells containing different ribozyme variants, in medium containing 20 µg/mL chloramphenicol. The parent ribozyme (0 Mut), the most efficient, evolved ribozyme (12 Mut; black), and ribozyme M4 (4 Mut; green) are labeled with the ...
Gregory F. Dolan (514033) +2 more
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Ribozyme cleavage is prone to enantiomeric contaminations.
, 2015 l-hammerhead ribozyme solution (2 μM) was artificially contaminated with enantiomeric d-ribozyme (20 nM–200 fM) and cleavage of d-RNA substrate was analyzed after 5 h at 37°C. Assays were performed in 50 mM Tris, pH 7.5 in the presence of (A) 10 mM MgCl2
Kai Hoehlig (697665) +2 more
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