Results 111 to 120 of about 16,956 (222)

A hammerhead ribozyme cleaves its target RNA during RNA preparation

A chemically modified hammerhead ribozyme was designed to cleave the tax RNA of human T cell leukemia virus type I. This ribozyme was exogenously delivered to tax-transformed fibroblasts by DOTAP-mediated transfection.
Xu X, Nerenberg M, Heidenreich O
core  

Oligonucleotide facilitators may inhibit or activate a hammerhead ribozyme

, 1996
Facilitators are oligonucleotides capable of affecting hammerhead ribozyme activity by interacting with the substrate at the termini of the ribozyme. Facilitator effects were determined in vitro using a system consisting of a ribozyme with 7 nucleotides ...
Bernd Schwenzer, Eckhard Jankowsky
core  

A GTP synthase ribozyme with increased GTP turnover. [PDF]

Proc Natl Acad Sci U S A
Han X, Pepper ZJ, Arriola JT, Müller UF.   +3 more
europepmc   +1 more source

Kinetics of hairpin ribozyme cleavage in yeast

, 2008
Hairpin ribozymes catalyze a self-cleavage reaction that provides a simple model for quantitative analyses of intracellular mechanisms of RNA catalysis.
Donahue, Christine Patricia, Fedor, Martha J.   +1 more
core  

Alkyltransferase Ribozyme for Site-Specific N⁴-Cytidine Alkylation. [PDF]

Angew Chem Int Ed Engl
Dorinova E, Walunj MB, Höbartner C.
europepmc   +1 more source

Intracellular Hairpin Ribozyme Catalysis: a Dissertation

, 2006
In the process of seeking author's permission to provide full text.Ribozymes are catalytic RNA molecules capable of performing functions normally attributed to proteins.
Donahue, Christine Patricia
core  

Rational design of hammerhead ribozymes as CD93 silencing tools for vascular diseases. [PDF]

Mol Ther Nucleic Acids
Perrone CD, Raucci L, Papini S, Tosi GM, Galvagni F, Olivucci M, Incarnato D, Orlandini M.   +7 more
europepmc   +1 more source

Cellular-state control using ribozyme-scaffolded miRNA-sensing and CRISPR-mediated actuation. [PDF]

Cell Rep Methods
Kang T, Bleris L.
europepmc   +1 more source

Site-specific ribozyme-mediated alkylation of DNA substrates. [PDF]

Nucleic Acids Res
He Y, Wilson TJ, Deng J, Luo Y, Yan K, Xie Y, Lilley DMJ, Huang L.   +7 more
europepmc   +1 more source

A small polymerase ribozyme that can synthesize itself and its complementary strand. [PDF]

Science
Gianni E, Kwok SLY, Wan CJK, Goeij K, Clifton BE, Colizzi ES, Attwater J, Holliger P.   +7 more
europepmc   +1 more source