Results 141 to 150 of about 28,198 (287)
Targeted insertion of large DNA fragments through templateājumping prime editing in rice
Plant Biotechnology Journal, EarlyView.
Fei Li+8 more
wiley +1 more source
Encoding folding paths of RNA switches [PDF]
RNA co-transcriptional folding has long been suspected to play an active role in helping proper native folding of ribozymes and structured regulatory motifs in mRNA untranslated regions. Yet, the underlying mechanisms and coding requirements for efficient co-transcriptional folding remain unclear.
arxiv
Importance of independence in ribozyme reactions: kinetic behavior of trimmed and of simply connected multiple ribozymes with potential activity against human immunodeficiency virus. [PDF]
Jun Ohkawa+4 more
openalex +1 more source
Inverse folding of RNA pseudoknot structures [PDF]
Background: RNA exhibits a variety of structural configurations. Here we consider a structure to be tantamount to the noncrossing Watson-Crick and \pairGU-base pairings (secondary structure) and additional cross-serial base pairs. These interactions are called pseudoknots and are observed across the whole spectrum of RNA functionalities.
arxiv
Inverse Folding of RNA Pseudoknot Structures [PDF]
Background: RNA exhibits a variety of structural configurations. Here we consider a structure to be tantamount to the noncrossing Watson-Crick and \pairGU-base pairings (secondary structure) and additional cross-serial base pairs. These interactions are called pseudoknots and are observed across the whole spectrum of RNA functionalities. In the context
arxiv
Ribozymes, recognition and evolution
Precision in the recognition and orientation of substrate is important in the selectivity of catalysis by natural enzymes. Several new ribozyme species have been evolved using in vitro selection/mutagenesis which make use of precise substrate recognition to catalyze a variety of reactions.
openaire +3 more sources
Construction of a ribozyme directed against human interleukin-6 mRNA: evaluation of its catalytic activity in vitro and in vivo [PDF]
M. Mahieu+4 more
openalex +1 more source
Specific gene suppression by engineered ribozymes in monkey cells.
Fiona Cameron, Patricia A. Jennings
openalex +1 more source
Erratum: DNA cleavage catalysed by the ribozyme from Tetrahymena [PDF]
Daniel Herschlag, Thomas R. Cech
openalex +1 more source