Synthesis of circular RNA in bacteria and yeast using RNA cyclase ribozymes derived from a group I intron of phage T4. [PDF]
, 1994 E. Ford, Manuel Ares
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Ribozyme-mediated attenuation of pancreatic beta-cell glucokinase expression in transgenic mice results in impaired glucose-induced insulin secretion. [PDF]
, 1994 Shimon Efrat +9 more
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Complete RNA inverse folding: computational design of functional hammerhead ribozymes
, 2014 Nanotechnology and synthetic biology currently constitute one of the most innovative, interdisciplinary fields of research, poised to radically transform society in the 21st century. This paper concerns the synthetic design of ribonucleic acid molecules,
Clote, Peter +5 more
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Importance of independence in ribozyme reactions: kinetic behavior of trimmed and of simply connected multiple ribozymes with potential activity against human immunodeficiency virus. [PDF]
, 1993 Jun Ohkawa +4 more
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Self-cleavage activity of the genomic HDV ribozyme in the presence of various divalent metal ions [PDF]
, 1993 YoungâAh Suh +3 more
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Three phases in the evolution of the standard genetic code: how translation could get started [PDF]
, 2007 A primordial genetic code is proposed, having only four codons assigned, GGC meaning glycine, GAC meaning aspartate/glutamate, GCC meaning alanine-like and GUC meaning valine-like.
van der Gulik, Peter
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A hammerhead ribozyme allows synthesis of a new form of theTetrahymenaribozyme homogeneous in length with a 3' end blocked for transesterification [PDF]
, 1991 Cheryl A. Grosshans, Thomas R. Cech
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Ribozymes, recognition and evolution
Chemistry & Biology, 1995 Precision in the recognition and orientation of substrate is important in the selectivity of catalysis by natural enzymes. Several new ribozyme species have been evolved using in vitro selection/mutagenesis which make use of precise substrate recognition to catalyze a variety of reactions.
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T. thermophila group I introns that cleave amide bonds [PDF]
, 1997 The present invention relates to nucleic acid enzymes or enzymatic RNA molecules that are capable of cleaving a variety of bonds, including phosphodiester bonds and amide bonds, in a variety of substrates.
Joyce, Gerald F.
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