Results 91 to 100 of about 10,488 (210)
Questions and answers about ricin [PDF]
Ricin is a poison found naturally in castor beans. If castor beans are chewed and swallowed, the released ricin can cause injury. Ricin can be made from the waste material left over from processing castor beans.
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Serum toxicokinetics of ricin.
, 2013 A. Concentrations of ricin in mouse sera over 480 min post -intoxication. Ricin content was determined by IPCR. B. Concentrations of ricin in mouse sera from 2 to 30 min post-intoxication illustrating early and rapid sequestration of ricin with a t1/2α ...
Xiaohua He (361530) +4 more
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Toxins, 2017 Ricin, a highly toxic plant-derived toxin, is considered a potential weapon in biowarfare and bioterrorism due to its pronounced toxicity, high availability, and ease of preparation.
Yoav Gal +6 more
doaj +1 more source
Endocytosis and retrograde transport of Shiga toxin and ricin
, 2009 The plant toxin ricin and the bacterial toxin Shiga toxin are not only a threat to human health but may also be used in cancer treatment and to gain new insight into the mechanisms of intracellular transport.
Utskarpen, Audrun
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The cytosolic fate of ricin A chain in target cells [PDF]
Ricin is a heterodimeric, toxic plant protein. It is able to deliver its catalytic A chain (RTA) into the cytosol of target cells. RTA crosses the endoplasmic reticulum (ER) membrane into the cytosol, masquerading as a substrate of ER-associated ...
Hart, Philip John
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Neutralization of ricin with polyclonal ricin antibodies.
, 2013 Survival percentage of mice dosed iv (A) or ig (B) with ricin were plotted over 160 h post-intoxication. Goat anti-ricin antibodies were introduced iv either prior-to or post-intoxication at indicated times.
Xiaohua He (361530) +4 more
core +1 more source
Effects of ricin on primary pulmonary alveolar macrophages
Journal of International Medical Research, 2019 Objective We systematically investigated the cytotoxic effects of ricin in primary pulmonary alveolar macrophages (PAMs). Methods Primary PAMs were isolated from BALB/c mice.
Zhendong Guo +11 more
doaj +1 more source
Inhibitors of the Cellular Trafficking of Ricin
Toxins, 2012 Throughout the last decade, efforts to identify and develop effective inhibitors of the ricin toxin have focused on targeting its N-glycosidase activity.
Daniel Gillet +3 more
doaj +1 more source
Exploiting the retrograde transport of disarmed toxins for the delivery of exogenous antigens into MHC class 1 presentation pathway [PDF]
The targeting of exogenous antigen into the MHC class 1-restricted presentation pathway is required for the induction of cytotoxic T lymphocytes (CTL) which have been shown to be an important component of the protective response to intracellular ...
Noakes, Karen
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