Results 81 to 90 of about 7,580 (168)
Ricin Toxin Activates the NALP3 Inflammasome
Ricin exhibits well characterized ribotoxic actions that lead to the inhibition of protein synthesis and the phosphorylation of stress activated protein kinases (SAPKs).
Meghan Lindauer, John Wong, Bruce Magun
doaj +1 more source
Ricin, a highly toxic plant-derived toxin, is considered a potential weapon in biowarfare and bioterrorism due to its pronounced toxicity, high availability, and ease of preparation.
Yoav Gal +6 more
doaj +1 more source
Inhibitors of the Cellular Trafficking of Ricin
Throughout the last decade, efforts to identify and develop effective inhibitors of the ricin toxin have focused on targeting its N-glycosidase activity.
Daniel Gillet +3 more
doaj +1 more source
Role of the Mannose Receptor (CD206) in Innate Immunity to Ricin Toxin
The entry of ricin toxin into macrophages and certain other cell types in the spleen and liver results in toxin-induced inflammation, tissue damage and organ failure.
Emily Gage +4 more
doaj +1 more source
The plant toxin ricin binds to terminal galactose-containing cell-surface receptors. The toxin is endocytosed and transported to the Golgi apparatus. Recent evidence suggests that ricin binds to galactosylated calreticulin, which may carry the toxin from the Golgi apparatus to the endoplasmic reticulum (ER).
openaire +2 more sources
Liposome‐mediated ricin toxicity in ricin‐resistant cells
Dimitriadis, Giorgos J. +1 more
openaire +2 more sources

