Results 141 to 150 of about 72,471 (294)

Mechanisms of Antibiotic Resistance and Novel Therapeutic Approaches for Mycobacterium tuberculosis: A Narrative Review With a Focus on Tuberculosis Mutations in Iran

open access: yesHealth Science Reports, Volume 8, Issue 10, October 2025.
ABSTRACT Background and Aims Tuberculosis, caused by Mycobacterium tuberculosis (M. tuberculosis), is a highly contagious disease and one of the leading causes of mortality globally. The emergence and dissemination of multidrug‐resistant (MDR) strains of M. tuberculosis have become a major concern, especially in developing countries.
Ali Bayat Bodaghi   +5 more
wiley   +1 more source

Combinations of Antibiotics Effective against Extensively- and Pandrug-Resistant Acinetobacter baumannii Patient Isolates

open access: yesMicroorganisms
Infections due to drug-resistant Acinetobacter baumannii strains are increasing and cause significant morbidity and mortality, especially in hospitalized and critically ill patients. A.
Justin Halim   +7 more
doaj   +1 more source

Emapalumab for Maladaptive Interferon‐γ‐Mediated Inflammation in Drug Reaction With Eosinophilia and Systemic Symptoms Complicating First‐Line Antituberculosis Therapy

open access: yes
Pediatric Blood &Cancer, Volume 72, Issue 12, December 2025.
Yahya Almodallal   +4 more
wiley   +1 more source

Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib

open access: yesThe Journal of Clinical Pharmacology, Volume 65, Issue 10, Page 1273-1285, October 2025.
Abstract Fruquintinib (FRUZAQLATM) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3). Two Phase 1, open‐label, single‐dose studies investigated the impact of hepatic or renal impairment on the pharmacokinetics and tolerability of fruquintinib.
Martha Gonzalez   +8 more
wiley   +1 more source

Study Design and Rationale for The Breathe Easier With Tadalafil Therapy for Exercise‐Related Dyspnea in COPD‐PH (BETTER COPD‐PH)

open access: yesPulmonary Circulation, Volume 15, Issue 4, October 2025.
ABSTRACT Dyspnea, a debilitating symptom of COPD, worsens health‐related quality of life (HRQL), reduces daily physical activity, increases health care utilization, and is more closely associated with survival than airflow limitation. Thus, having treatments that reduce dyspnea in COPD is important.
Elena DeSanti   +40 more
wiley   +1 more source

The Microbiome in Hidradenitis Suppurativa Tunnels: A Systematic Review

open access: yesInternational Journal of Dermatology, Volume 64, Issue 10, Page 1802-1812, October 2025.
ABSTRACT Hidradenitis suppurativa (HS) is a chronic inflammatory disease that affects the pilosebaceous units, particularly in large skin folds. The pathophysiology of HS is multifactorial, with evidence suggesting that the microbiome plays a crucial role in perpetuating inflammation.
Alberto Soto‐Moreno   +6 more
wiley   +1 more source

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