Results 61 to 70 of about 4,155,575 (342)

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

A process planning system with feature based neural network search strategy for aluminum extrusion die manufacturing [PDF]

open access: yesAsian International Journal of Science and Technology in Production and Manufacturing Engineering 2, 1 (2009) 137-157, 2009
Aluminum extrusion die manufacturing is a critical task for productive improvement and increasing potential of competition in aluminum extrusion industry. It causes to meet the efficiency not only consistent quality but also time and production cost reduction.
arxiv  

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

¿Derecho a morir con dignidad?

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2008
El derecho a morir con dignidad es un concepto vago y que recibe múltiples interpretaciones, muchas de ellas inapropiadas. Se propone la necesidad de que sea el médico quien se haga responsable de proteger los derechos del paciente, de garantizar el uso ...
Álvaro Ruiz
doaj   +1 more source

Plausible Suggestion for a Deterministic Wave Function [PDF]

open access: yesarXiv, 2006
A deterministic axial vector model for photons is presented which is suitable also for particles. During a rotation around an axis the deterministic wave function a has the following form a = ws r exp(+-i wb t). ws is either the axial or scalar spin rotation frequency (the latter is proportional to the mass), r radius of the orbit (also amplitude of a ...
arxiv  

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

The Right to Die [PDF]

open access: yes, 2013
In this thesis, I argue that, with certain procedural safeguards in place, physician‐assisted death (PAD) and euthanasia are morally permissible and should be an option for terminally ill patients.
Steenburn, Samantha
core   +1 more source

A Treatise on Sucker's Bets [PDF]

open access: yesarXiv, 2017
In 1970, Statistics giant, Bradley Efron, amazed the world by coming up with a set of four dice, let's call them A,B,C,D, whose faces are marked with [0,0,4,4,4,4], [3,3,3,3,3,3],[2,2,2,2,6,6],[1,1,1,5,5,5] respectively, where die A beats die B, die B beats die C, die C beats die D, but, surprise surprise, die D beats die A!
arxiv  

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Raumzeitkonzeptionen in der Quantengravitation (Spacetime in Quantum Gravity) [PDF]

open access: yesarXiv, 2011
The book gives an overview over the possible perspectives with regard to our conceptions of space and time in the transition from General Relativity to a future theory of Quantum Gravity. Here the most different approaches and strategies for a theory construction in the field of Quantum Gravity are taken into account.
arxiv  

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