Gradualism vs Cold Turkey : how to establish credibility for the ECB [PDF]
The paper analyzes the incentive for the ECB to establish reputation by pursuing a restrictive policy right at the start of its operation. The bank is modelled as risk averse with respect to deviations of both inflation and output from her target.
Illing, Gerhard
core
Older Lesbians, Gay Men and the ‘Right to Die’ debate - ‘I always keep a lethal dose of something, because I don’t want to become an elderly isolated person.' [PDF]
This article considers the ‘right to die’ debate from the perspectives of older lesbians and gay men, drawing upon data gathered for a PhD in law. My argument is that older lesbians and gay men are multiply disadvantaged (a) by an increased risk of ...
Westwood, SL
core +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Diretivas antecipadas de vontade: percurso histórico na América Latina
Resumo As diretivas antecipadas de vontade são instrumento para garantir ao paciente o direito de decidir sobre seus cuidados de saúde, especialmente os relacionados ao fim da vida.
Renata da Silva Fontes Monteiro +1 more
doaj +1 more source
End of Life Care: The Importance of Culture and Ethnicity [PDF]
Despite Australia's cultural diversity, there is little doubt that ethnic minority groups continue to have less access to health care systems, let alone culturally appropriate care, including palliative and end of life care.
Jane Phillips
core
Diverse disparities: The politics and economics of wage, market and disposable income inequalities [PDF]
This paper analyzes the evolution of inequality and its determinants across different forms of income. A number of results emerge from this effort. First, OECD countries have been and continue to be much more diverse in their distributions of earnings ...
Beramendi, Pablo, Cusack, Thomas R.
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
The adaptation of the therapeutic effort: science, technology and society
The scientific and technological development has an impact in all the spheres of society. The adaptation of the therapeutic effort is example of this. The author’s motive to carry out this bibliographic review article laid on the technological abuse as a
Gilberto de Jesús Betancourt-Betancourt +2 more
doaj

