Results 71 to 80 of about 8,230,084 (364)

Autophagy in cancer and protein conformational disorders

open access: yesFEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

WRC Assessment re PCCS Garment Co. Ltd. (Cambodia): Findings, Recommendations and Status [PDF]

open access: yes, 2008
WRC assessment detailing labor violations in the areas of health and safety, harassment and abuse, and legally-mandated benefits at a PCCS Garment factory in ...
Worker Rights Consortium
core   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

WRC Assessment re Tos Dominicana (Dominican Republic): Findings and Recommendations [PDF]

open access: yes, 2007
WRC report on its assessment of labor violations at a Tos Dominicana factory operating in the Dominican Republic, inclusive of recommendations for remedial ...
Worker Rights Consortium
core   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

The Thomistic Perception of the Person and Human Rights [PDF]

open access: yesStudia Gilsoniana, 2017
The idea of human rights is connected to the modern perception of law founded on subjectivity, in the context of which rights are authorizations of individual action versus a higher authority, resulting in a subjectivity of law.
Eleni Procopiou
doaj  

Case Summary: Double Star (Thailand) [PDF]

open access: yes, 2006
WRC report on its investigation of various labor violations at the Double Star factory in Thailand. Describes the exchanges between WRC and the company to remediate working conditions, which resulted in better treatment of union members, but failed to ...
Worker Rights Consortium
core   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Should politicians be prosecute for statements made in the exercise of their mandate?

open access: yesCrítica Penal y Poder, 2019
http://assembly.coe.int/nw/xml/XRef/Xref-XML2HTML-en.asp?fileid=25279&lang=en http://assembly.coe.int/nw/xml/XRef/Xref-XML2HTML-FR.asp?fileid=25279&lang ...
Boris Cilevičs, Committee on Legal Affairs and Human Rights
doaj  

Legal Protection of the Rights of Older Persons against Ageism

open access: yesAge of Human Rights Journal, 2018
Human beings go through stages of vulnerability during their evolution and development. Old age is one of these. The rights of older persons are acknowledged to a certain degree but have not yet been developed into an integral system like the rights of ...
M. Pilar Munuera Gómez   +1 more
doaj   +1 more source

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